Erratum: Title Correction. The Role of The Effects of Vitamin D Supplementation on Bone Mineral Density and Bone Mineral Content in Ovariectomized Rats Compensation in Rats

Background: Postmenopausal osteoporosis progressively occurs due to alteration in the estrogen level during the menopause period, and subsequently elevates the risk of fractures. Objective: To evaluate the effect of regular resistance exercise, vitamin D, and calcium supplements on bone mineral content and density, postmenopausal rats used. Materials and Methods: In this experimental study, 72 female Sprague-Dawley rats (8-10 wk: 250 ± 15 gr) were ovariectomized and randomly divided into nine groups (n = 8/each): control, placebo, exercise (EX), exercise with vitamin D supplement (EX + D), exercise with calcium (EX + Ca), exercise with calcium and vitamin D (EX + Ca + D), vitamin D administration (D), calcium administration (Ca), and calcium and vitamin D (Ca + D) groups. Finally, the tail, hip, and lumbar bone mineral content, bone mineral density, bone thickness, and bone cells were evaluated in each group. Results: The tail, hip, and lumbar bone mineral density was increased significantly in the EX + Vit D group compared to the control group (p = 0.004, p = 0.007, p = 0.003, respectively). However, there were no significant changes in the bone mineral content of the hips and lumbar among the groups. Besides, bone thickness in the Ex + Vit D group was more than the other groups (p = 0.02). The number of osteoclast cells decreased in the Ca + Vit D, Ex + Ca, Ex + Vit D, and Ex + Vit D + Ca groups compared to the control group. Osteocyte numbers were increased only in the Ex + Vit D group. Conclusion: Resistance exercise in combination with vitamin D and calcium have a positive effect on the bone mineral density and bone mineral content and might be able to prevent or delay the osteoporosis among elderly women. However, additional researches are needed to assess the molecular pathways of this process. Key words: Menopause, Vitamin D, Exercise, Calcium, Bone mineral density.

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Role of vitamin D levels and vitamin D supplementation on bone mineral density in Klinefelter syndrome

Endocrine Abstracts ◽

10.1530/endoabs.37.gp.10.08 ◽

2015 ◽

Author(s):

Alberto Ferlin ◽

Riccardo Selice ◽

Mambro Antonella Di ◽

Marco Ghezzi ◽

Nicola Caretta ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Klinefelter Syndrome ◽

Vitamin D Supplementation ◽

Mineral Density ◽

Vitamin D Levels

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Vitamin D Status is Associated With Bone Mineral Density and Bone Mineral Content in Preschool-Aged Children

Journal of Clinical Densitometry ◽

10.1016/j.jocd.2014.04.121 ◽

2015 ◽

Vol 18 (1) ◽

pp. 60-67 ◽

Cited By ~ 10

Author(s):

Tom J. Hazell ◽

Thu Trang Pham ◽

Sonia Jean-Philippe ◽

Sarah L. Finch ◽

Jessy El Hayek ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral Content ◽

Bone Mineral ◽

Mineral Content ◽

Vitamin D Status ◽

Mineral Density ◽

Preschool Aged Children

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Role of vitamin D levels and vitamin D supplementation on bone mineral density in Klinefelter syndrome

Osteoporosis International ◽

10.1007/s00198-015-3136-8 ◽

2015 ◽

Vol 26 (8) ◽

pp. 2193-2202 ◽

Cited By ~ 29

Author(s):

A. Ferlin ◽

R. Selice ◽

A. Di Mambro ◽

M. Ghezzi ◽

A. Di Nisio ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Klinefelter Syndrome ◽

Vitamin D Supplementation ◽

Mineral Density ◽

Vitamin D Levels

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Influence of anthropometric parameters on assessment of paediatric bone mineral density and bone mineral content

Bone Abstracts ◽

10.1530/boneabs.2.p18 ◽

2013 ◽

Author(s):

N Hangartner Thomas ◽

F Short David ◽

Gilsanz Vicente ◽

J Kalkwarf Heidi ◽

M Lappe Joan ◽

...

Keyword(s):

Bone Mineral Density ◽

Bone Mineral Content ◽

Bone Mineral ◽

Mineral Content ◽

Mineral Density ◽

Anthropometric Parameters

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Bone mineral density at age 7 years does not associate with adherence to vitamin D supplementation guidelines in infancy or vitamin D status in pregnancy and childhood: An Odense Child Cohort study

British Journal Of Nutrition ◽

10.1017/s0007114521000301 ◽

2021 ◽

pp. 1-33

Author(s):

Signe Monrad Nørgaard ◽

Christine Dalgård ◽

Malene Søborg Heidemann ◽

Anders Jørgen Schou ◽

Henrik Thybo Christesen

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Vitamin D Supplementation ◽

Vitamin D Status ◽

Mineral Density ◽

Mineral Concentration ◽

High Adherence ◽

Bone Mineralisation ◽

In Pregnancy

Abstract Vitamin D supplementation in infancy is recommended to prevent rickets. At the population level, its effects on bone mineralisation are largely unknown. We aimed to explore whether adherence to national vitamin D supplementation guidelines (10 µg/day up to age 2 years), supplementation at ages 5 and 7 years, and serum 25-hydroxyvitamin D (s-25(OH)D) at various time points associated with bone mineral density (BMD) at age 7 years in the Odense Child Cohort, Denmark (n=1,194). High adherence was defined as supplementation with 10 µg vitamin D 6-7 times per week during ≥ 80 % of the observation time. S-25(OH)D was analysed using liquid chromatography-tandem mass spectrometry. Total-body-less-head (TBLH) BMD was measured by dual-energy X-ray absorptiometry. At median age 18.1 months, 53.9 % (n=475/881) reported high adherence. The median s-25(OH)D was 64.7, 78.8, 46.0, and 71.8 nmol/l in early pregnancy, late pregnancy, cord blood, and at 5 years, respectively. The mean (SD) TBLH BMD at median age 7.1 years was 0.613 (0.049) g/cm2 (z-score +0.363 (0.824)). In adjusted analyses, vitamin D supplementation up to 18 months, and at 5 and 7 years, was not associated with TBLH BMD. Similarly, no robust associations were found between TBLH BMD and s-25(OH)D at any time point. No associations were found for TBLH bone mineral concentration or bone area. In this population with relatively high s-25(OH)D concentrations, no consistent associations were found between adherence to vitamin D supplementation recommendations or vitamin D status in pregnancy or childhood, and bone mineralisation at age 7 years.

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Effects of One-Year Adjuvant Treatment with Tamoxifen on Bone Mineral Density in Postmenopausal Breast Cancer Women

Tumori Journal ◽

10.1177/030089169608200114 ◽

1996 ◽

Vol 82 (1) ◽

pp. 65-67 ◽

Cited By ~ 10

Author(s):

Sandro Barni ◽

Paolo Lissoni ◽

Gabriele Tancini ◽

Antonio Ardizzoia ◽

Marina Cazzaniga

Keyword(s):

Breast Cancer ◽

Bone Mineral Density ◽

Alkaline Phosphatase ◽

Bone Mineral Content ◽

Bone Mineral ◽

Adjuvant Treatment ◽

Mineral Content ◽

Postmenopausal Breast Cancer ◽

Mineral Density ◽

One Year

In this study, the authors have analyzed the possible effects of one-year adjuvant treatment with tamoxifen on bone mineral density in postmenopausal breast cancer women. Bone mineral content was studied by photon absorptiometry (I-125), whereas bone balance was analyzed indirectly by serum PTH, osteocalcin, calcitonin, calcium and alkaline phosphatase levels. Bone mineral content and serum bone-related substances were measured before starting treatment and after one year. Results were analyzed using Student's t test for paired data. No difference was found between the two measurements for bone mineral content, PTH, calcitonin, calcium and alkaline phosphatase levels. Measurements at entry and after one year of treatment showed a statistically significant difference ( P < 0.001) only for osteocalcin. In accordance with other authors, we can conclude that treatment with tamoxifen does not cause an increase in menopausal bone resorption. The finding that osteocalcin levels decreased after one year of therapy with tamoxifen is interesting, but further studies are necessary to clarify the role of such levels in predicting a turnover of bone balance towards osteoblastic activity.

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