Antimicrobial nano-fiber structures development to rejuvenate injured dura mater in brain surgery

2019 ◽  
Vol 09 ◽  
Author(s):  
Hanin Bashir
Keyword(s):  
Dura Mater ◽  
Brain Surgery ◽  
Nano Fiber

scholarly journals Multilayered Artificial Dura-Mater Models for a Minimally Invasive Brain Surgery Simulator

2020 ◽  
Vol 10 (24) ◽  
pp. 9000
Author(s):  
Masaru Takeuchi ◽  
Shusaku Hayakawa ◽  
Akihiko Ichikawa ◽  
Akiyuki Hasegawa ◽  
Yasuhisa Hasegawa ◽  
...  
Keyword(s):  
Tensile Stress ◽  
Minimally Invasive ◽  
Dura Mater ◽  
Mechanical Characteristics ◽  
Pituitary Surgery ◽  
Multilayered Structure ◽  
Brain Surgery ◽  
Rubber Material ◽  
Fiber Sheet ◽  
Surgery Simulator

In this study, new artificial dura-mater models were developed using a multilayered structure of a rubber material (represent an elastic component of a dura-mater) and a fiber sheet (represent fiber component of a dura-mater). The artificial dura-mater models were prepared for use in a brain surgery simulator, especially for transnasal pituitary surgery. The mechanical characteristics of the artificial dura-mater models were tested to check the similarities with porcine dura-mater. Tensile stress, viscoelasticity, and the cutting force generated by microscissors were tested to evaluate the fabricated models. Neurosurgeons also assessed the dura-mater models to evaluate their characteristics. The results indicate that these models made of two different non-woven fiber sheets emulated accurately the actual dura-mater.

Ultrastructural evidence for mast cell-macrophage interrelationships in the dura mater of the rat: Infrequent mast cell-nerve associations

1990 ◽  
Vol 48 (3) ◽  
pp. 352-353
Author(s):  
Ruth V.W. Dimlich
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Dura Mater ◽  
Spatial Relationship ◽  
Potassium Phosphate ◽  
Plasma Extravasation ◽  
Close Spatial Relationship ◽  
Male Wistar Rats ◽  
Headache Pain ◽  
Relationship Of

Mast cells in the dura mater of the rat may play a role in cerebral pathologies including neurogenic inflammation (vasodilation; plasma extravasation) and headache pain . As has been suggested for other tissues, dural mast cells may exhibit a close spatial relationship to nerves. There has been no detailed ultrastructural description of mast cells in this tissue; therefore, the goals of this study were to provide this analysis and to determine the spatial relationship of mast cells to nerves and other components of the dura mater in the rat.Four adult anesthetized male Wistar rats (290-400 g) were fixed by perfusion through the heart with 2% glutaraldehyde and 2.8% paraformaldehyde in a potassium phosphate buffer (pH 7.4) for 30 min. The head of each rat was removed and stored in fixative for a minimum of 24 h at which time the dural coverings were removed and dissected into samples that included the middle meningeal vasculature. Samples were routinely processed and flat embedded in LX 112. Thick (1 um) sections from a minimum of 3 blocks per rat were stained with toluidine blue (0.5% aqueous).

Who Knew Brain Surgery Could Be So Much Fun?

PsycCRITIQUES ◽  
2015 ◽  
Vol 60 (4) ◽  
Author(s):  
James W. Kalat
Keyword(s):  
Brain Surgery

Metastasierendes malignes Melanom mit Festliegen ante partum infolge Rückenmarkskompression bei einer Stute

2013 ◽  
Vol 41 (03) ◽  
pp. 190-194
Author(s):  
K. Jäger ◽  
A. Snyder ◽  
A. Sobiraj ◽  
L. Hildebrandt
Keyword(s):  
Dura Mater ◽  
Malignes Melanom

ZusammenfassungDer Fallbericht beschreibt die Einengung des Rückenmarkskanals durch ein malignes Melanom mit resultierendem akutem Festliegen bei einer hochtragenden, 17 Jahre alten Welsh-B-Ponystute. Als ursächlich für das akute Festliegen war der Einbruch von Metastasen des malignen Melanoms in den Wirbelkanal im Bereich der letzten Lendenwirbel und des Kreuzbeins anzusehen, wo der Tumor die Dura mater infiltriert und das Lenden- sowie Sakralmark auf einer Länge von 10 cm mittelgradig komprimiert hatte. Dargestellt werden neben dem klinischen Bild labordiagnostische, pathologisch-anatomische und histopathologische Befunde.

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