A Rational Approach towards the Development of Human Carbonic Anhydrase Inhibitors as Antiepileptic Agent

2-Benzylsulfinylbenzoic acid binds to human carbonic anhydrase II in a mode completely different from any other class of carbonic anhydrase inhibitors investigated so far.

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2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.04.002 ◽

2018 ◽

Vol 151 ◽

pp. 363-375 ◽

Cited By ~ 16

Author(s):

Niccolò Chiaramonte ◽

Silvia Bua ◽

Marta Ferraroni ◽

Alessio Nocentini ◽

Alessandro Bonardi ◽

...

Keyword(s):

Intraocular Pressure ◽

Carbonic Anhydrase ◽

Enzyme Inhibition ◽

Carbonic Anhydrase Inhibitors ◽

New Class ◽

Pressure Lowering ◽

Human Carbonic Anhydrase

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Synthesis and structure–affinity relationship of chlorinated pyrrolidinone-bearing benzenesulfonamides as human carbonic anhydrase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103658 ◽

2020 ◽

Vol 97 ◽

pp. 103658 ◽

Cited By ~ 1

Author(s):

Benas Balandis ◽

Guostė Ivanauskaitė ◽

Joana Smirnovienė ◽

Kristina Kantminienė ◽

Daumantas Matulis ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase ◽

Relationship Of

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Next-generation polyamine human carbonic anhydrase inhibitors

Targeting Carbonic Anhydrases ◽

10.4155/fseb2013.13.13 ◽

2014 ◽

pp. 68-81

Author(s):

Fabrizio Carta ◽

Andrea Scozzafava

Keyword(s):

Carbonic Anhydrase ◽

Next Generation ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase

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Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2013.07.044 ◽

2013 ◽

Vol 21 (19) ◽

pp. 5973-5982 ◽

Cited By ~ 14

Author(s):

Kalyan K. Sethi ◽

Daniella Vullo ◽

Saurabh M. Verma ◽

Muhammet Tanç ◽

Fabrizio Carta ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase

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Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.3109/14756366.2016.1156676 ◽

2016 ◽

Vol 31 (6) ◽

pp. 1707-1711 ◽

Cited By ~ 4

Author(s):

Mikhail Krasavin ◽

Roman Stavniichuk ◽

Sergey Zozulya ◽

Petro Borysko ◽

Daniela Vullo ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

New Class ◽

Differential Scanning Fluorimetry ◽

Human Carbonic Anhydrase

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Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.11.073 ◽

2019 ◽

Vol 163 ◽

pp. 443-452 ◽

Cited By ~ 11

Author(s):

Maria Rosa Buemi ◽

Anna Di Fiore ◽

Laura De Luca ◽

Andrea Angeli ◽

Francesca Mancuso ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Structural Properties ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase

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The Synthesis of Atomoxetine-containing Carboxamides - Potential Human Carbonic Anhydrase Inhibitors

American Chemical Science Journal ◽

10.9734/acsj/2016/22245 ◽

2016 ◽

Vol 10 (3) ◽

pp. 1-5

Author(s):

Anton Shetnev ◽

Angelina Osipyan ◽

Alexander Sapegin ◽

Mikhail Dorogov

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase

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