scholarly journals Clinical significance and prognostic value of C-reactive protein/albumin ratio in gastric cancer

2021 ◽  
Vol 100 (6) ◽  
pp. 338
Author(s):  
Qian Yu ◽  
Ke-zhi Li ◽  
Yan-jun Fu ◽  
Yanping Tang ◽  
Xin-qiang Liang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Prognostic Value ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein

Clinical significance and prognostic value of C-reactive protein/albumin ratio in gastric cancer

2020 ◽  
Author(s):  
Yan-jun Fu ◽  
Ke-zhi Li ◽  
Xin-qiang Liang ◽  
Zhi-qing Liang ◽  
Bai jihong
Keyword(s):  
Gastric Cancer ◽  
Overall Survival ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Prognostic Value ◽  
Tnm Stage ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Gastric Cancer Patients

Abstract Background C-reactive protein/albumin ratio (CAR) is a novel prognostic biomarker in several malignancies. This study was aimed to evaluate the clinical significance and prognostic value of CAR in patients with gastric cancer. Methods The data of 205 gastric cancer patients who underwent surgery was retrospectively reviewed. The association with the clinical features and prognostic value of CAR in gastric cancer was analyzed. The data of this study was combined with previous studies to further determine the prognostic value of CAR in patients with gastric cancer. Results Cox analysis revealed that preoperative CAR was an independent prognosis indicator in patients with gastric cancer. High expression of CAR indicated a shorter survival time than those with lower expression. CAR has a higher prognostic value in the 1-, 3-, 5-years of overall survival in patients with gastric cancer. However, CAR has no significant difference regarding the gastric cancer patients’ age, gender and TNM stage. The discriminated value of CAR in TNM stage of gastric cancer was moderate. A meta-analysis by combining previous data and our data showed that preoperative CAR was significantly associated with the overall survival of patients with gastric cancer. Conclusions This study demonstrated that preoperative CAR was an independent prognostic indicator in the patients with gastric cancer who underwent surgery.

scholarly journals Prognostic role of the pretreatment C-reactive protein/albumin ratio in gastric cancer

Medicine ◽  
2020 ◽  
Vol 99 (10) ◽  
pp. e19362
Author(s):  
Xuanxuan Yang ◽  
Xing Song ◽  
Luo Zhang ◽  
Changping Wu
Keyword(s):  
Gastric Cancer ◽  
C Reactive Protein ◽  
Prognostic Role ◽  
Albumin Ratio ◽  
Reactive Protein

scholarly journals The prognostic value of C-reactive protein to albumin ratio in patients with lung cancer

Medicine ◽  
2018 ◽  
Vol 97 (50) ◽  
pp. e13505 ◽  
Author(s):  
Tai-Bing Deng ◽  
Jing Zhang ◽  
Yong-Zhao Zhou ◽  
Wei-Min Li
Keyword(s):  
Lung Cancer ◽  
Prognostic Value ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein

scholarly journals Prognostic role of pre-treatment C-reactive protein/albumin ratio in esophageal cancer: a meta-analysis

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Zhenhua Liu ◽  
Hongtai Shi ◽  
Longyun Chen
Keyword(s):  
Esophageal Cancer ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Pooled Analysis ◽  
Cochrane Library ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Pre Treatment

Abstract Background In recent years, the role of pre-treatment C-reactive protein/albumin ratio (CAR) in prognosis of esophageal cancer (EC) has been investigated by several studies. This meta-analysis aimed to provide a more accurate and objective assessment of the prognostic value of pre-treatment CAR in EC. Methods Studies assessing the role of pre-treatment CAR in prognosis of EC were searched from PubMed, Embase and the Cochrane Library (last update by April 16, 2019). The hazard ratios (HRs) of CAR and the corresponding 95% CIs for overall survival (OS) or cancer-specific survival (CSS) in EC were extracted for pooled analysis. Results A total of eight observational studies including 2255 patients were collected. The pooled analysis showed that high CAR was related to worse OS in EC (pooled HR = 1.81; 95% CI = 1.40–2.35; P < 0.001). Subgroup analyses showed that the negative correlation between the CAR and OS was consistently demonstrated in subgroups stratified by country, pathological type, and cut-off value (P < 0.05). However, there was no relation between CAR and OS in subgroup of patients receiving neoadjuvant chemotherapy at a proportion of 100% (HR = 1.15, 95% CI = 0.56–2.69; P = 0.715). In addition, high CAR was also related to worse CSS in EC (pooled HR = 2.61; 95% CI = 1.67–4.06; P < 0.001). Conclusions High pre-treatment CAR was an adverse prognostic factor for EC patients. More large-sample clinical trials are still needed to verify the prognostic value of pre-treatment CAR in EC.

Clinical Burden of C-Reactive Protein/Albumin Ratio before Curative Surgery for Gastric Cancer Patients

2017 ◽  
Vol 225 (4) ◽  
pp. S187
Author(s):  
Yuji Toiyama ◽  
Yasuhiko Mohri ◽  
Tadanobu Shimura ◽  
Hiromi Yasuda ◽  
Hiroyuki Fujikawa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
C Reactive Protein ◽  
Curative Surgery ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Clinical Burden ◽  
Gastric Cancer Patients
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