scholarly journals Application of H-Point Standard Addition Method and Multivariate Calibration Methods to the Simultaneous Kinetic-Potentiometric Determination of Cerium(IV) and Dichoromate

2010 ◽  
Vol 01 (02) ◽  
pp. 73-82 ◽  
Author(s):  
Mohammad Ali Karimi ◽  
Mohammad Hossein Mashhadizadeh ◽  
Mohammad Mazloum-Ardakani ◽  
Fatemeh Rahavian
Keyword(s):  
Multivariate Calibration ◽  
Standard Addition ◽  
Standard Addition Method ◽  
Potentiometric Determination ◽  
Addition Method ◽  
Calibration Methods

scholarly journals Simultaneous Determination of Antazoline and Naphazoline by the Net Analyte Signal Standard Addition Method and Spectrophotometric Technique

2010 ◽  
Vol 93 (6) ◽  
pp. 1995-2001 ◽  
Author(s):  
Karim Asadpour-Zeynali ◽  
Raoof Ghavami ◽  
Roghayeh Esfandiari ◽  
Payam Soheili-Azad
Keyword(s):  
Simultaneous Determination ◽  
Multivariate Calibration ◽  
Standard Addition ◽  
Single Step ◽  
Standard Addition Method ◽  
Addition Method ◽  
Net Analyte Signal ◽  
Analyte Signal ◽  
Calibration Methods

Abstract A novel net analyte signal standard addition method (NASSAM) was used for simultaneous determination of the drugs anthazoline and naphazoline. The NASSAM can be applied for determination of analytes in the presence of known interferents. The proposed method is used to eliminate the calibration and prediction steps of multivariate calibration methods; the determination is carried out in a single step for each analyte. The accuracy of the predictions against the H-point standard addition method is independent of the shape of the analyte and interferent spectra. The net analyte signal concept was also used to calculate multivariate analytical figures of merit, such as LOD, selectivity, and sensitivity. The method was successfully applied to the simultaneous determination of anthazoline and naphazoline in a commercial eye drop sample.

Sign in / Sign up

Export Citation Format

Share Document