scholarly journals Dura Mater: Anatomy and Clinical Implication

2021 ◽  
Vol 11 (10) ◽  
pp. 239-247
Author(s):  
Mehmet Ünal ◽  
Ahmet Burak Sezgin
Keyword(s):  
Dura Mater ◽  
Clinical Implication

scholarly journals The posterior cranial fossa's dura mater innervation and its clinical implication in headache: a comprehensive review

2021 ◽  
Author(s):  
D. Hage ◽  
M. Mathkour ◽  
J. Iwanaga ◽  
A. S. Dumont ◽  
R. S. Tubbs
Keyword(s):  
Dura Mater ◽  
Clinical Implication ◽  
Comprehensive Review

Ultrastructural evidence for mast cell-macrophage interrelationships in the dura mater of the rat: Infrequent mast cell-nerve associations

1990 ◽  
Vol 48 (3) ◽  
pp. 352-353
Author(s):  
Ruth V.W. Dimlich
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Dura Mater ◽  
Spatial Relationship ◽  
Potassium Phosphate ◽  
Plasma Extravasation ◽  
Close Spatial Relationship ◽  
Male Wistar Rats ◽  
Headache Pain ◽  
Relationship Of

Mast cells in the dura mater of the rat may play a role in cerebral pathologies including neurogenic inflammation (vasodilation; plasma extravasation) and headache pain . As has been suggested for other tissues, dural mast cells may exhibit a close spatial relationship to nerves. There has been no detailed ultrastructural description of mast cells in this tissue; therefore, the goals of this study were to provide this analysis and to determine the spatial relationship of mast cells to nerves and other components of the dura mater in the rat.Four adult anesthetized male Wistar rats (290-400 g) were fixed by perfusion through the heart with 2% glutaraldehyde and 2.8% paraformaldehyde in a potassium phosphate buffer (pH 7.4) for 30 min. The head of each rat was removed and stored in fixative for a minimum of 24 h at which time the dural coverings were removed and dissected into samples that included the middle meningeal vasculature. Samples were routinely processed and flat embedded in LX 112. Thick (1 um) sections from a minimum of 3 blocks per rat were stained with toluidine blue (0.5% aqueous).

I1307K APC gene variant has no clinical implication in Israeli jews at average or high risk for colorectal neoplasia

2001 ◽  
Vol 120 (5) ◽  
pp. A120-A121
Author(s):  
H STRUL ◽  
E BIRENBAUM ◽  
B STERN ◽  
D KAZANOV ◽  
L THEODOR ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Implication ◽  
Colorectal Neoplasia ◽  
Apc Gene ◽  
Gene Variant

Metastasierendes malignes Melanom mit Festliegen ante partum infolge Rückenmarkskompression bei einer Stute

2013 ◽  
Vol 41 (03) ◽  
pp. 190-194
Author(s):  
K. Jäger ◽  
A. Snyder ◽  
A. Sobiraj ◽  
L. Hildebrandt
Keyword(s):  
Dura Mater ◽  
Malignes Melanom

ZusammenfassungDer Fallbericht beschreibt die Einengung des Rückenmarkskanals durch ein malignes Melanom mit resultierendem akutem Festliegen bei einer hochtragenden, 17 Jahre alten Welsh-B-Ponystute. Als ursächlich für das akute Festliegen war der Einbruch von Metastasen des malignen Melanoms in den Wirbelkanal im Bereich der letzten Lendenwirbel und des Kreuzbeins anzusehen, wo der Tumor die Dura mater infiltriert und das Lenden- sowie Sakralmark auf einer Länge von 10 cm mittelgradig komprimiert hatte. Dargestellt werden neben dem klinischen Bild labordiagnostische, pathologisch-anatomische und histopathologische Befunde.

Meningeal Layer of the Dura Mater

2020 ◽  
Author(s):  
Keyword(s):  
Dura Mater

Microsurgical anatomy and treatment of dural defects in spontaneous spinal cerebrospinal fluid leaks

2020 ◽  
pp. 1-9
Author(s):  
Ako Matsuhashi ◽  
Keisuke Takai ◽  
Makoto Taniguchi
Keyword(s):  
Dura Mater ◽  
Fat Grafting ◽  
Thoracolumbar Junction ◽  
Microsurgical Anatomy ◽  
Dural Defect ◽  
Ct Myelography ◽  
Blood Patch ◽  
Neurosurgical Treatment ◽  
Dural Defects ◽  
Csf Leaks

OBJECTIVESpontaneous spinal CSF leaks are caused by abnormalities of the spinal dura mater. Although most cases are treated conservatively or with an epidural blood patch, some intractable cases require neurosurgical treatment. However, previous reports are limited to a small number of cases. Preoperative detection and localization of spinal dural defects are difficult, and surgical repair of these defects is technically challenging. The authors present the anatomical characteristics of dural defects and surgical techniques in treating spontaneous CSF leaks.METHODSAmong the consecutive patients who were diagnosed with spontaneous CSF leaks at the authors’ institution between 2010 and 2020, those who required neurosurgical treatment were included in the study. All patients’ clinical information, radiological studies, surgical notes, and outcomes were reviewed retrospectively. Outcomes of two different procedures in repairing dural defects were compared.RESULTSAmong 77 patients diagnosed with spontaneous CSF leaks, 21 patients (15 men; mean age 57 years) underwent neurosurgery. Dural defects were detected by FIESTA MRI in 7 patients, by CT myelography in 12, by digital subtraction myelography in 1, and by dynamic CT myelography in 1. The spinal levels of the defects were localized at the cervicothoracic junction in 16 patients (76%) and thoracolumbar junction in 4 (19%). Intraoperative findings revealed that the dural defects were small, circumscribed longitudinal slits located at the ventral aspect of the dura mater. The median dural defect size was 5 × 2 mm. The presence of dural defects at the thoracolumbar junction was associated with manifestation of an altered mental status, which was an unusual manifestation of CSF leaks (p = 0.003). Eight patients were treated via the posterior transdural approach with watertight primary sutures of the ventral defects, and 13 were treated with muscle or fat grafting. Regardless of the two different procedures, postoperative MRI showed either complete disappearance or significant reduction of the extradural CSF collection. No patient experienced postoperative neurological deficits. Clinical symptoms improved or stabilized in 20 patients with a median follow-up of 12 months.CONCLUSIONSDural defects in spontaneous CSF leaks were small, circumscribed longitudinal slits located ventral to the spinal cord at either the cervicothoracic or thoracolumbar junction. Muscle/fat grafting may be an alternative treatment to watertight primary sutures of ventral dural defects with a good outcome.

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