"First-in-man" MitraClip via pulmonary vein access through a right mini-thoracotomy in a patient with agenesis of the inferior vena cava

2015 ◽  
Vol 10 (11) ◽  
pp. 1204-1207 ◽  
Author(s):  
Klaus Tiroch ◽  
Hilmar Brinkmann ◽  
Dimitrios Koudonas ◽  
Marc Vorpahl ◽  
Melchior Seyfarth ◽  
...  
1971 ◽  
Vol 55 (1) ◽  
pp. 47-61
Author(s):  
DANIEL P. TOEWS ◽  
G. SHELTON ◽  
D. J. RANDALL

1. Oxygen and carbon dioxide tensions were determined in the lungs and in blood from the dorsal aorta, pulmonary vein, pulmonary artery and inferior vena cava in the intact, free swimming, Amphiuma. At 15° C this animal was submerged for a large part of the time and surfaced briefly to breathe at variable time intervals, the mean period being 45 min. 2. Oxygen tensions in the lungs and in all blood vessels oscillated with the breathing cycles, falling gradually during the period of submersion and rising rapidly after the animal breathed. The absolute level of oxygen tension did not appear to constitute the effective signal beginning or ending a series of breathing movements. 3. A small oxygen gradient existed between lungs and blood in the pulmonary vein immediately after a breath. The gradient increased in size as an animal remained submerged due, it is suggested, to lung vasoconstriction increasing the transfer factor. 4. Blood in the dorsal aorta had a lower oxygen tension than that in the pulmonary vein. A right-to-left shunt occurred as blood moved through the heart. The degree of shunting increased as the animal remained submerged and pulmonary vasoconstriction occurred. Left-to-right shunt was relatively insignificant since oxygen tensions in the inferior vena cava and pulmonary artery were very similar. 5. Carbon dioxide tensions were relatively constant during the breathing-diving cycle since Amphiuma removed almost all of this gas through the skin.


1998 ◽  
Vol 1 (5) ◽  
pp. 413-419 ◽  
Author(s):  
Ulrike Bartram ◽  
Stella Van Praagh ◽  
John F. Keane ◽  
Peter Lang ◽  
Mary E. van der Velde ◽  
...  

A newborn female infant was found to have a unique and previously unreported group of anomalies: ( 1) mitral and aortic atresia with a highly obstructive atrial septum; ( 2) hypoplasia of the right lung with a crossover segment involving the right lower lobe; ( 3) normally connected pulmonary veins, two from the left lung and one from the right; and ( 4) a large anomalous branch of the right pulmonary vein of scimitar configuration that anastomosed with the normally connected right pulmonary vein and with the inferior vena cava (IVC). The scimitar vein appeared obstructed at its junction with the right pulmonary vein and at its junction with the inferior vena cava within the hepatic parenchyma. To our knowledge, this is the first report of a scimitar-like vein coexisting with mitral and aortic atresia and connecting both with the right pulmonary vein and with the inferior vena cava. The highly obstructed left atrium was partially decompressed by retrograde blood flow via the normally connected right pulmonary vein to the anomalous scimitar venous pathway and thence to the inferior vena cava via a pulmonary-to-IVC collateral vein.


1967 ◽  
Vol 45 (3) ◽  
pp. 463-473 ◽  
Author(s):  
Don P. MacLeod ◽  
E. G. Hunter

Preparations of rat superior and inferior vena cava and pulmonary vein behave essentially as preparations of atrial and ventricular muscle in response to electrical stimulation and a variety of drugs. In addition, rat inferior vena cava has spontaneous rhythmic activity. Epinephrine, norepinephrine, isoproterenol, and phenylephrine had positive inotropic effects in all three preparations and a positive chronotropic effect in inferior vena cava. All these responses were blocked by propranolol but unaffected by tolazoline. Acetylcholine and carbachol produced a negative inotropic effect in all three preparations and a negative chronotropic effect in inferior vena cava. These responses were blocked by atropine but unaffected by hexamethonium. Angiotensin, histamine, serotonin, and pitocin were without effect on the three preparations studied although slight positive inotropic effects were observed from time to time with angiotensin and serotonin. Transmembrane action potentials of the pulmonary vein and inferior vena cava were compared with those of rat ventricular strips and isolated atria in their response to acetylcholine. The response of preparations of vein was similar to that of atrial muscle in that acetylcholine reduced the duration of the action potentials.


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