scholarly journals Case Report: Molecular Detection of Dirofilaria repens in an Italian Patient after a Stay in Tanzania

2021 ◽  
Author(s):  
Donato Antonio Raele ◽  
Nicola Pugliese ◽  
Gianfranco LaBella ◽  
Agata Calvario ◽  
Maria Scarasciulli ◽  
...  
Keyword(s):  
Case Report ◽  
Molecular Detection ◽  
Isothermal Amplification ◽  
Dirofilaria Repens ◽  
Italian Patient ◽  
Molecular Assays ◽  
Acanthocheilonema Viteae ◽  
Patient Reported ◽  
Knott’S Test

A 35-year-old man was admitted to a hospital in the south of Italy because of a periocular nodule and subpalpebral edema. The patient reported having been stayed in Tanzania five months before. Hematologic parameters were within the normality range, the Acanthocheilonema viteae ELISA did not detect significant levels of antifilarial IgG, and no further symptoms were described. The surgical inspection of the nodule led to the isolation of two filarioid parasites, identified as Dirofilaria repens by SEM, and then by molecular assays. Knott’s test did not reveal microfilaremia, whereas loop-mediated isothermal amplification and PCR detected D. repens DNA. The patient was treated with doxycycline, and he was found no more positive at the follow-up.

Bevacizumab-induced dysphonia: A case report with brief review of literature

2019 ◽  
Vol 26 (4) ◽  
pp. 1032-1036
Author(s):  
So Yi Lam ◽  
Chung-Shien Lee ◽  
Sandhya Sharma ◽  
Kit Cheng
Keyword(s):  
Ovarian Cancer ◽  
Case Report ◽  
Side Effect ◽  
Case Reports ◽  
Palliative Therapy ◽  
Ovarian Adenocarcinoma ◽  
Voice Changes ◽  
Patient Reported ◽  
Rare Side Effect

Introduction Anti-angiogenic treatment in adjunct with chemotherapy is widely used for the treatment of various cancers. These agents inhibit vascular endothelial growth factor (VEGF) signaling thereby inhibiting tumor proliferation and invasion. Dysphonia, or voice changes, has been documented, but is an underreported side effect of anti-angiogenic agents. We report a case of intermittent dysphonia in a patient with metastatic, platinum-refractory ovarian cancer treated with bevacizumab. Case report A 48-year-old female with high grade mixed type ovarian adenocarcinoma and concurrent left sided breast cancer was transitioned to palliative therapy with gemcitabine-bevacizumab for her ovarian cancer. At a follow-up visit after three cycles of the new therapy, the patient complained of intermittent changes in her voice, describing periods of hoarseness or softness in her voice after the chemotherapy—sometimes to the point that her voice was inaudible. Management and outcome: A new pelvic thrombus was discovered upon assessment of the patient’s disease. Bevacizumab was held and she was referred to ear, nose, and throat evaluation for dysphonia. Laryngoscopic examination showed normal vocal cord, with normal movements and no lesion or necrosis. During subsequent follow-up, the patient reported improvement in her voice with no additional dysphonia. Discussion Vocal adverse effects of anti-VEGF agents have been documented in landmark trials and case reports; however, clinicians are often unaware of this rare side effect. Although VEGF-induced dysphonia may be rare and may not impede the patient’s quality of life in some cases, it is critical to acknowledge and not underestimate this adverse effect.

scholarly journals Penetrating Orbitocranial Injury With a Good Aesthetic and Functional Outcome: A Case Report

2021 ◽  
Vol 7 (1) ◽  
pp. 61-66
Author(s):  
Youssef Fahde ◽  
◽  
Davis Mpando ◽  
Mehdi Laghmari ◽  
Houssine Ghannane ◽  
...  
Keyword(s):  
Case Report ◽  
Multidisciplinary Approach ◽  
Violent Behavior ◽  
Case Presentation ◽  
Frontal Horn ◽  
Patient Reported ◽  
Long Term Follow Up ◽  
Life Threatening

Background and Importance: Transorbitocranial assaults with sharp objects like a knife are rare neuro-ophthalmologic emergencies. However, they can have dramatic functional and life-threatening consequences. Our presentation aims to report the importance of an urgent multidisciplinary approach and to raise awareness among the general population on the importance of preventing violent behavior. Case Presentation: A 33-year-old man was a victim of a knife attack without obvious brain or ophthalmological lesions. The knife entered the medial part of the orbit. Neurological examination was normal, and Computed Tomography (CT) scan showed intracranial trajectory through the orbit to the frontal horn of the lateral ventricle. The knife was extracted without complications. The patient reported spectacular improvement in visual acuity without neurological or oculomotor deficit at long-term follow-up. In this case report, we will discuss the radiological diagnosis and surgical management of transorbital and orbitocranial injuries by foreign body penetration. Conclusion: Urgent multidisciplinary management in orbitocranial trauma by stabbing is mandatory to avoid life-threatening complications and irreversible damages.

scholarly journals Case Report

Hand ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. NP38-NP40 ◽  
Author(s):  
Sanjay Naran ◽  
Joseph E. Imbriglia
Keyword(s):  
Case Report ◽  
Donor Site ◽  
Donor Site Morbidity ◽  
No Donor ◽  
Metacarpophalangeal Joints ◽  
Active Function ◽  
Patient Reported ◽  
Long Term Follow Up

Background: A case is discussed in which a young girl was born with symbrachydactyly of multiple digits in whom nonvascularized proximal toe phalanges were transferred to the aphalangic digits at the age of four. At 39 years of age, she presented incidentally to our clinic and was observed to have a very functional hand with mobile metacarpophalangeal joints in all reconstructed digits. Methods: We present a case report which is discussed in the context of long-term follow-up, and phalangeal growth in the absence of distraction, and a review of the current literature in regards to outcomes for this modality of treatment. Results: We document growth of the transplanted phalanges, despite surgery occurring after the reported optimum age of before 18 months, and the patient not undergoing distraction. The patient reported no donor site morbidity in regards to function or psychosocial impact. Furthermore, we observed active function at the metacarpophalangeal joints of all operated digits. Conclusions: We report the longest follow-up (35 years) following nonvascularized proximal toe phalangeal transfer for short finger type symbrachydactyly. We highlight the long-term functional outcome of nonvascularized toe phalangeal transfers, and present an overview of the current outcome literature for this type of procedure, advocating that nonvascularized toe phalangeal transfers remain a viable treatment option for select cases of symbrachydactyly.

scholarly journals Mini-implants: Alternative for Oral Rehabilitation of a Child with Ectodermal Dysplasia

2015 ◽  
Vol 26 (1) ◽  
pp. 75-78 ◽  
Author(s):  
Bianca Zeponi Fernandes Mello ◽  
Thiago Cruvinel Silva ◽  
Daniela Rios ◽  
Maria Aparecida Andrade Moreira Machado ◽  
Fabrício Pinelli Valarelli ◽  
...  
Keyword(s):  
Case Report ◽  
Ectodermal Dysplasia ◽  
Oral Rehabilitation ◽  
Mini Implants ◽  
Prosthesis Retention ◽  
Patient Reported ◽  
Long Term Follow Up ◽  
Socialization Skills

Ectodermal dysplasia is a rare congenital disease that affects several structures of ectodermal origin. The most commonly related oral characteristics are hypodontia, malformed teeth and underdeveloped alveolar ridges. New alternative treatments are needed due to the failure of the conventional prosthesis retention. This case report outlines the oral rehabilitation treatment of a 9-year-old girl with ectodermal dysplasia. The treatment was performed with conventional prosthesis upon mini-implants. The mini-implants provided prosthetic retention. The patient reported a good adaptation of the dental prosthesis and satisfaction with the treatment. The increased self-esteem improved the socialization skills of the girl. In this case report, use of prosthesis with mini-implants was satisfactory for prosthetic retention. However, clinical studies with long-term follow-up are needed to test the mini-implants as an alternative for oral rehabilitation of children with ectodermal dysplasia.

Use of the Tissue Stress Model as a Paradigm for Developing an Examination and Management Plan for a Patient with Plantar Fasciitis

2002 ◽  
Vol 92 (9) ◽  
pp. 499-506 ◽  
Author(s):  
Michael Ross
Keyword(s):  
Case Report ◽  
Plantar Fasciitis ◽  
Plantar Fascia ◽  
Management Plan ◽  
Stress Model ◽  
Patient History ◽  
Stress Treatment ◽  
Patient Reported ◽  
History Of

This case report demonstrates the use of the tissue stress model to develop an examination, evaluation, and management plan for a patient with an 8-week history of plantar fasciitis. The patient history focused on determining which tissues were being excessively stressed, and the physical examination was used to apply controlled stresses to these tissues and to determine factors contributing to the patient’s condition. After it was confirmed that the patient’s plantar fascia was under excessive mechanical stress, treatment first focused on reducing pain, inflammation, and stress on the plantar fascia and then on returning the patient to her running program while maintaining symptoms at a diminished level. The patient reported being free of pain 7 weeks after the initial physical therapy examination and at the 11-week telephone follow-up. Although no experimental evidence is given, this report suggests that this patient responded positively to treatment based on the tissue stress model. (J Am Podiatr Med Assoc 92(9): 499-506, 2002)

scholarly journals MTHFR GENE MUTATION AND ITS REPERCUSSION IN THE GENESIS AND TREATMENT OF DEPRESSION: CASE REPORT

2021 ◽  
Vol 9 (07) ◽  
pp. 415-421
Author(s):  
Alexandre Leal Laux ◽  
Alana Klochinski ◽  
Bruna Bobato ◽  
Evelyn Suquebski Dib ◽  
Harien Sprung ◽  
...  
Keyword(s):  
Case Report ◽  
Gene Mutation ◽  
Gene Mutations ◽  
Mthfr Gene ◽  
Major Depressive ◽  
Double Mutation ◽  
Residual Symptoms ◽  
Treatment Of Depression ◽  
Patient Reported

This study aims to report the correlation of MTHFR gene mutation with the genesis of depression and antidepressants non-response in a patient, highlighting the importance of genetic investigation and indicating the replacement of L-methylfolate as an effective treatment adjuvant. This is a case report of a patient diagnosed with major depressive disorder, refractory to pharmacological therapies, in monotherapy or combination therapy, and psychotherapy. After 1 year and 4 months of persistent residual symptoms, genetic testing of the MTHFR gene was requested with confirmation of a heterozygous double mutation of MTHFR. This gene polymorphism can result in deficiency of L-methylfolate, which is related to psychiatric diseases and refractoriness to antidepressant therapy. With the introduction of l-methylfolate 15mg, the patient reported remission of depressive symptoms in 4 months of follow-up. MTHFR gene mutations influence the action of folate, favoring depression and leading to refractory response to conventional treatment.

When Gingival Recession Is Rescued By Periodontal Plastic Surgery: A Clinical Case Report

2017 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Case Report ◽  
Surgical Techniques ◽  
Gingival Recession ◽  
Root Surface ◽  
Root Coverage ◽  
Patient Reported ◽  
Term Evaluation ◽  
Periodontal Plastic Surgery

Gingival recession is the most common mucogingival defect. It is characterized by the exposure of the tooth root surface resulting from displacement of the gingival margin below the cementoenamel junction. The denuded root surfaces compromise dental and gingival aesthetics with dentine hypersensitivity, caries proclivity, cervical abrasion and oral hygiene disability. When deciding root coverage, settled surgical techniques have been proposed and each procedure challenges to expand on limitations of the others. The purpose of this case report is to assess the esthetic correction of localized gingival recession using combined coronally positioned flap with connective tissue graft techniques. Long term evaluation, extended to two years after surgical treatment, is performed. The part of the prophylactic management to prevent potential future recessions is also enhanced. Significant increasing in keratinized and attached gingival tissues and reduction of height and width of recession were obtained. Gain of root coverage was 100% with great improvement in attachment level. Prevention of recession was accomplished and the results were stable after two years follow up. Patient-reported outcomes were satisfaction and esthetic appearance.

Benign Schwannoma of the Lateral Plantar Nerve: A Case Report

2020 ◽  
Vol 110 (6) ◽  
Author(s):  
Hayden L. Hoffler ◽  
Rebecca M. Steele ◽  
Christina S. Long
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Foot And Ankle ◽  
Lateral Plantar Nerve ◽  
Benign Schwannoma ◽  
Patient Reported ◽  
Painful Mass ◽  
Histopathologic Analysis

Schwannomas are benign, encapsulated soft-tissue tumors that rarely present to the foot and ankle. These tumors are usually asymptomatic unless an increase in size or disruption of the nerve causes pain. We report a case of a painful mass along the lateral plantar nerve near the fourth metatarsal base that was surgically excised and confirmed as a benign schwannoma by means of histopathologic analysis. At the final follow-up of over 2 years, the patient reported no pain, neurologic deficits, or signs of recurrence. This case demonstrates an unusual location of a schwannoma arising from the lateral plantar nerve.

scholarly journals Restorative treatment in a case of amelogenesis imperfecta and 9-year follow-up: a case report

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Martin M. I. Sabandal ◽  
Till Dammaschke ◽  
Edgar Schäfer
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Marked Improvement ◽  
Amelogenesis Imperfecta ◽  
Case Presentation ◽  
Restorative Treatment ◽  
Retrospective Assessment ◽  
Patient Reported

Abstract Background Amelogenesis imperfecta is a hereditary malformation showing various manifestations regarding enamel dysplasia. This case report shows a 9-year follow-up after restorative treatment of a 16-year old female patient affected by a hypoplastic type of amelogenesis imperfecta. The caries-free, hypersensitive teeth of the patient were restored by direct dentin adhesive composite restorations performed in total etch technique. Case presentation After rehabilitation the patient reported a marked improvement of the mastication ability and quality of life especially during food intake. Accumulation of plaque was reduced and the ability to perform adequate oral hygiene was improved. During follow-up of 9 years recurring secondary caries and debonding of fillings were recognized and retreated. Conclusions The retrospective assessment exhibits that the performed restorative treatment prolonged the time until further treatment has to be considered, such as prosthetic treatment.

scholarly journals Cefixime and Ofloxacin fixed dose combination induced petechial rash: a case report

2016 ◽  
Vol 6 (1) ◽  
pp. 211
Author(s):  
Sudhir Kumar ◽  
Kirti Nirmal ◽  
Amit Kumar Nirmal ◽  
S. K. Bhattacharya
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Fixed Dose Combination ◽  
Local Application ◽  
Fixed Dose ◽  
Petechial Rash ◽  
Patient Reported ◽  
Dose Combination

Petechial rash is a type of rash which is associated with many infectious and non-infectious conditions. We present a case of Petechial rash induced by administration of cefixime with ofloxacin tablet. A eighteen year old male patient reported to us with a presentation of rash with itching for three days on administration of the fixed dose combination of cefixime + ofloxacin along with paracetamol for the previous symptoms of fever with chills, headache and bodyache. Patient describes itching in the rash which is increasing. The duty doctor attended the patient and immediately stopped the further administration of the offending medication. The patient was prescribed tablet cetirizine orally along with calamine lotion for local application. The patient reported back in for follow-up and was without any residual rashes or other such complaints. He was advised to remember and cautious from the use of drugs in the offending category.

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