ESA-CNES' 1994 Long-Term Bed-Rest Study: 42 Days Of Head-Down Tilt, A Simulation For Long Duration Manned Space Flights.

1995 ◽  
Author(s):  
A. Maillet ◽  
A. Bichi ◽  
L. Decramer
Author(s):  
Yu. Akatov ◽  
E.E. Kovalev ◽  
V.A. Sakovich ◽  
S. Deme ◽  
I. Fehér ◽  
...  

2019 ◽  
Vol 204 ◽  
pp. 04007
Author(s):  
Elena Kolesnikova ◽  
Aleksandr Bugay

Radiation-induced impairment of hippocampal neurogenesis is one of serious factors associated with cognitive detriments after radiation therapy of brain cancers and realization of long-term manned space flights. The goal of this study is to develop a mathematical model describing radiation-induced changes in cellular populations participating in neurogenesis and how these alterations worsen the processing of information by hippocampus. Modeling results have demonstrated that heavy ions may cause non-reversible suppression of neurogenesis, which is followed by failure of pattern encoding and retrieval by hippocampal neural networks.


2020 ◽  
Vol 25 (1) ◽  
pp. 45-53
Author(s):  
L.B. Strogonova ◽  
◽  
Yu.A. Vasin ◽  
R.A. Gardunio ◽  
A.N. Knyazev ◽  
...  

Since April 1961, all manned space flights have been accompanied by medical control ensuring flight safety. Medical control in space flight has a technological and medical methodology that allows, at a distance from medical specialists, to make an adequate medical decision for the current situation. This work would be impossible if there were no measures taken to unify and standardize equipment and techniques. Telemedicine technologies developed on the basis of flight medical control. The origin of the word telemedicine comes from the expression «telemetric medical information», adopted in space technology. The issues of mutual development and mutual enrichment, standardization of methods and equipment of two areas of medicine, medical control in extreme situations and general telemedicine are considered in this article.


2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Ilario Puglia ◽  
Michele Balsamo ◽  
Marco Vukich ◽  
Valfredo Zolesi

The study and analysis of human physiology during short- and long-duration space flights are the most valuable approach in order to evaluate the effect of microgravity on the human body and to develop possible countermeasures in prevision of future exploratory missions and Mars expeditions. Hand performances such as force output and manipulation capacity are fundamental for astronauts’ intra- and extravehicular activities. Previous studies on upper limb conducted on astronauts during short-term missions (10 days) indicated a temporary partial reduction in the handgrip maximum voluntary contraction (MVC) followed by a prompt recovery and adaptation to weightlessness during the last days of the mission. In the present study, we report on the “Crew’s Health: Investigation on Reduced Operability” (CHIRO) protocol, developed for handgrip and pinch force investigations, performed during the six months increment 7 and increment 8 (2003-2004) onboard International Space Station (ISS). We found that handgrip and pinch force performance are reduced during long-term increments in space and are not followed by adaptation during the mission, as conversely reported during short-term increment experiments. The application of protocols developed in space will be eligible to astronauts during long-term space missions and to patients affected by muscle atrophy diseases or nervous system injury on Earth.


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