scholarly journals Acceptance and Quality Control Tests for the Single Photon Emission Computerized Tomography (SPECT) Gamma Cameras and SPECT/CT Systems

2020 ◽  
Vol 6 (2) ◽  
pp. 38-50
Author(s):  
Semra Dönmez ◽  
Aslı Ayan ◽  
Yasemin Parlak ◽  
Bilal Kovan ◽  
Meral Hiçürkmez ◽  
...  
Keyword(s):  
Quality Control ◽  
Computerized Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Single Photon Emission ◽  
Gamma Cameras

Diagnostic value of 201Tl—single-photon emission computerized tomography studies in cases of posterior fossa hemangioblastomas

2001 ◽  
Vol 95 (2) ◽  
pp. 292-297 ◽  
Author(s):  
Takeo Kondo ◽  
Toshihiro Kumabe ◽  
Shin Maruoka ◽  
Takashi Yoshimoto
Keyword(s):  
Computerized Tomography ◽  
Posterior Fossa ◽  
Single Photon ◽  
Photon Emission ◽  
Magnetic Resonance Images ◽  
Thallium 201 ◽  
Homologous Region ◽  
Single Photon Emission ◽  
Content Type ◽  
Fine Print

Object. The 201Tl uptake index was evaluated for its usefulness in formulating a diagnosis of hemangioblastoma. Thallium-201—single-photon emission computerized tomography (SPECT) studies were performed in nine patients harboring hemangioblastomas in the posterior fossa and in five patients (six lesions) with gliomas in the posterior fossa. Methods. The 201Tl uptake index was defined as the ratio of mean counts of isotope per pixel in the tumor to mean counts of isotope per pixel in the homologous region of the healthy brain. The 201Tl uptake indices of the early image (TlE) and that of the delayed image (TlD) were calculated. The isotope retention index (RI) was calculated as (TlE − TlD)/TlE. The TlE was 2.7 ± 0.7 in hemangioblastomas and 2.9 ± 1.7 in gliomas (mean ± standard deviation). The TlD was 1.5 ± 0.4 in hemangioblastomas and 2.4 ± 1.6 in gliomas. There were no significant differences between hemangioblastomas and gliomas when TlEs and TlDs were compared. The isotope RI was 0.43 ± 0.07 in hemangioblastomas and 0.15 ± 0.1 in gliomas, showing a significantly higher RI in hemangioblastomas compared with gliomas (p < 0.01). Conclusions. Thallium-201 washout is significantly faster in hemangioblastomas. Hemangioblastoma is biologically benign, but contains a rich capillary network that forms a hypervascular tumor bed. Variations in its appearance on magnetic resonance images may cause difficulties in the differential diagnosis of hemangioblastoma. Thallium-201 SPECT studies can be used to distinguish hemangioblastomas from gliomas in the posterior fossa.

In Vivo Quantitative Noninvasive Imaging of Gene Transfer by Single-Photon Emission Computerized Tomography

2003 ◽  
Vol 14 (3) ◽  
pp. 255-261 ◽  
Author(s):  
Alberto Auricchio ◽  
Paul D. Acton ◽  
Markus Hildinger ◽  
Jean-Pierre Louboutin ◽  
Karl Plössl ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Computerized Tomography ◽  
Single Photon ◽  
Noninvasive Imaging ◽  
Photon Emission ◽  
Single Photon Emission

SMALL-ANIMAL MOLECULAR IMAGING WITH PORTABLE DEVICES ON CLINICAL PINHOLE SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY SYSTEMS

2012 ◽  
Vol 24 (06) ◽  
pp. 485-493
Author(s):  
Chi-Min Hu ◽  
Ming-Shien Lin ◽  
Kuan-Hao Su ◽  
Ren-Shyan Liu ◽  
Jyh-Cheng Chen
Keyword(s):  
Molecular Imaging ◽  
Single Photon ◽  
Photon Emission ◽  
Small Animal ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Gamma Cameras ◽  
Portable System ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Objectives: We have developed a portable system compatible with various clinical gamma cameras to perform three-dimensional (3D) small-animal molecular imaging. The spatial resolution of this system is close to that of commercial animal imaging systems, although its cost is much lower. Methods: The portable system consists of a rotating stage, a leveling plate, a line source phantom, and a calibration phantom. To obtain high-resolution single-photon emission computed tomography (SPECT) images, we developed several methods for system alignment and applied geometric calibration. The projections of the subject were reimaged according to the calibration parameters and reconstructed by the 3D ordered subsets expectation maximization (OS-EM) algorithm. Results: The resulting images of the microdeluxe phantom showed 2.4-mm cold rods. The image quality of phantom scanning was stable when the portable system was applied to various gamma cameras from different manufacturers. The resultant images of a 99mTc-MDP bone scan of a mouse showed details of the spine, femur, pelvis, and tail. Furthermore, a radiopharmaceutical study of 99mTc-HYNIC-Annexin V on a liver inflammation-induced mouse was carried out to demonstrate the feasibility of this system for small-animal molecular imaging. Conclusions: The newly developed portable system was compatible with various gamma cameras and enabled successful performance of small-animal molecular imaging.

scholarly journals Cerebellar Diaschisis in Pontine Ischemia. A Case Report with Single-Photon Emission Computerized Tomography

1987 ◽  
Vol 7 (1) ◽  
pp. 127-131 ◽  
Author(s):  
D. Perani ◽  
G. Lucignani ◽  
P. Pantano ◽  
P. Gerundini ◽  
G. L. Lenzi ◽  
...  
Keyword(s):  
Case Report ◽  
Computerized Tomography ◽  
Acute Phase ◽  
Single Photon ◽  
Photon Emission ◽  
Single Photon Emission ◽  
Ischemic Lesion ◽  
Blood Flows ◽  
Cerebellar Diaschisis ◽  
Tomography Scan

Regional cerebral and cerebellar blood flows were studied by N, N, N'-trimethyl- N'-(2-hydroxy-3-methyl-5-[123I]iodobenzyl)-1,3-propanediamine 2 HC1 (1-123 HIPDM) and single-photon emission computerized tomography (SPECT) in a patient with an ischemic lesion of the pons. An asymmetry of perfusion of the cerebellar hemispheres, normal on transmission computerized tomography scan, was demonstrated by SPECT studies in the early acute phase and confirmed 15 days after. This finding may be related to the interruption of the corticopontocerebellar pathways.

Assessment of Postural Differences in Regional Pulmonary Perfusion in Man by Single-Photon Emission Computerized Tomography

1997 ◽  
Vol 92 (1) ◽  
pp. 81-85 ◽  
Author(s):  
David J. Ross ◽  
Pearl Wu ◽  
Zab Mohsenifar
Keyword(s):  
Computerized Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Normal Subjects ◽  
Pulmonary Perfusion ◽  
Single Photon Emission ◽  
Section Data ◽  
Coronal Section ◽  
Regression Slopes ◽  
End Tidal

1. With the advent of single-photon emission computerized tomography, controversy has arisen with regard to the significance of gravitational influences on regional pulmonary perfusion (Q̊r) in the supine versus prone postures. We investigated the dorsal—ventral distributions of Q̊r in prone (n = 5) and supine (n = 5) normal subjects, as assessed by single-photon emission computerized tomography after intravenous injection of technetium-99m-labelled macroaggregated albumin at end-tidal expiration. Reconstructed serial (one pixel thickness) coronal sections were traced on a computer screen, to yield the encompassed radioactive counts and number of pixels per each image. Coronal section data (expressed as mean radioactive counts/pixel) were expressed in a ‘profile’ and normalized to the maximum coronal section of each lung (%maximum). 2. Coefficients of variation and linear regression slopes for the prone versus supine profiles for left and right lungs were not statistically different (unpaired Student's t-test). The coronal section with maximum Q̊r was identified in the more dependent lung regions and, hence, affected by gravity. 3. We conclude that, in contrast to previous canine models, which have suggested postural differences in dorsal-ventral perfusion gradients, in normal man gravity primarily determines the non-dependent to dependent distribution of Q̊r. We speculate that interspecies differences in physiology may be teleological and related to the different perfusion demands of the quadruped compared with upright man.

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