scholarly journals A rare disease with pregnancy: Castleman case report

2021 ◽  
Vol 33 (4) ◽  
pp. 300-302
Author(s):  
Özen Esra Karaman ◽  
Çetin Kılıççı ◽  
Pelin Özdemir Önder
Keyword(s):  
Rare Disease ◽  
Preoperative Diagnosis ◽  
Perioperative Management ◽  
Castleman’S Disease ◽  
Lymphoid Hyperplasia ◽  
Lymphoproliferative Disease ◽  
Pathological Examination ◽  
Diagnostic Tools ◽  
Unknown Etiology ◽  
Castleman's Disease

Castleman’s disease was first described by Castleman et al. in 1956 as a non-lymphoproliferative disease. Castleman’s disease (CD), or angiofollicular lymphoid hyperplasia, is a rare disease with unknown etiology that can be easily misdiagnosed as lymphoma, neoplasm, or infection. Very few cases of pelvic origin and observed in pregnancy have been reported in the literature and are usually asymptomatic. Preoperative diagnosis is very difficult due to nonspecific imaging findings and rarity; most cases are diagnosed based on postoperative pathological examination. In this paper, a case of a 36-year-old pregnant woman suspected of adnexal origin in the uterine posterolateral, which was detected incidentally by ultrasound, was presented. The patient underwent a successful mass excision. Pathology of mass observed to be in the pelvic retroperitoneum was detected as localized unicentric and hyaline vascular CD. The study was conducted to discuss the diagnostic tools and perioperative management needed to identify the retroperitoneal unicentric Castleman case

scholarly journals Unicentric Castleman's Disease Arising from an Intrapulmonary Lymph Node

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Hideki Ota ◽  
Hideki Kawai ◽  
Tsubasa Matsuo
Keyword(s):  
Lymph Node ◽  
Ct Angiography ◽  
Preoperative Diagnosis ◽  
Castleman’S Disease ◽  
Unknown Etiology ◽  
Imaging Features ◽  
Castleman's Disease ◽  
3D Ct ◽  
Imaging Characteristics ◽  
3D Ct Angiography

Castleman's disease is an uncommon lymphoproliferative disorder of unknown etiology, most often involving the mediastinum. It has 2 distinct clinical forms: unicentric and multicentric. Unicentric Castleman's disease arising from an intrapulmonary lymph node is rare, and establishing a preoperative diagnosis of this disease is very difficult mainly due to a lack of specific imaging features. We report a case of intrapulmonary unicentric Castleman's disease in an asymptomatic 19-year-old male patient who was accurately diagnosed by preoperative computed tomography (CT). The mass was incidentally found on a routine chest X-ray. A subsequent dynamic CT showed a well-defined, hypervascular, soft-tissue mass with small calcifications located in the perihilar area of the right lower lung. Three-dimensional CT (3D-CT) angiography indicated that the mass was receiving its blood supply through a vascular network at its surface that originated from 2 right bronchial arteries. The clinical history and CT findings were consistent with a diagnosis of unicentric Castleman's disease, and we safely and successfully removed the tumor via video-assisted thoracoscopic surgical lobectomy. This case shows that the imaging characteristics of these rare tumors on contrast-enhanced CT combined with 3D-CT angiography can be helpful in reliably establishing a correct preoperative diagnosis.

scholarly journals Retroperitoneal pararenal castleman’s disease: a case report

2013 ◽  
Vol 3 (6) ◽  
pp. 509-511
Author(s):  
S Shrestha ◽  
U Nepal ◽  
N Lamichhane ◽  
P Chhetri
Keyword(s):  
Preoperative Diagnosis ◽  
Histopathological Examination ◽  
Castleman’S Disease ◽  
Accurate Diagnosis ◽  
Renal Tumors ◽  
Unknown Etiology ◽  
Resected Specimen ◽  
Castleman's Disease ◽  
Vascular Type ◽  
Hyaline Vascular Type

Castleman’s diseas is a rare lymphoproliferative disorder of unknown etiology. We report a 28 years old woman with solitary Castleman’s disease in the left pararenal space. This case was diagnosed preoperatively as renal cell carcinoma. The patient underwent a radical nephrectomy with dissection of pararenal mass. Histopathological examination of the surgically resected specimen showed the hyaline vascular type of Castleman’s disease. A preoperative diagnosis of Castleman’s disease is difficult; therefore, a surgical resection and histopathological evaluation can provide an accurate diagnosis of tumor. Taking this case into consideration, we suggest that Castleman’s disease should be included in the differential diagnosis of renal tumors. DOI: http://dx.doi.org/10.3126/jpn.v3i6.9004 Journal of Pathology of Nepal (2013) Vol. 3, 509-511

scholarly journals Castleman's Disease: An Intrapulmonary Form with Intrafissural Development

2009 ◽  
Vol 9 ◽  
pp. 940-945 ◽  
Author(s):  
Hajer Racil ◽  
Sana Cheikh Rouhou ◽  
Olfa Ismail ◽  
Saoussen Hantous-Zannad ◽  
Nawel Chaouch ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Castleman’S Disease ◽  
Lower Lobe ◽  
Unknown Etiology ◽  
Castleman's Disease ◽  
Curative Surgery ◽  
Abnormal Shadow ◽  
History Of ◽  
Chest X Ray ◽  
The Right

Castleman's disease (CD) is an uncommon, mainly benign, lymphoproliferative disorder of unknown etiology, mostly involving the mediastinum. Parenchymal lung involvement of the disease is exceedingly rare. We describe a case of CD in a 23-year-old woman with a 4-year history of recurring dyspnea and nonproductive cough, whose chest X-ray showed an abnormal shadow of the right hilum. Chest computed tomography confirmed the presence of a tissue-density mass of the right lower lobe, demonstrating poor contrast enhancement, associated with multiple laterotracheal and mediastinal lymphadenopathies. The patient underwent curative surgery, revealing a right hilar compressive mass, with an intrafissural development between the superior and middle lobes. Pneumonectomy was performed due to profuse bleeding. This case of CD is particular because of its unusual intrapulmonary location and its intrafissural development. Poor contrast enhancement is atypical in CD.

Reactive lymphoid hyperplasia of the liver characterized by an angiofollicular pattern mimicking Castleman's disease

1996 ◽  
Vol 46 (10) ◽  
pp. 782-786 ◽  
Author(s):  
Tohru Tanizawa ◽  
Yoshinobu Eishi ◽  
Ryuichi Kamiyama ◽  
Madoka Nakahara ◽  
Yoshihisa Abo ◽  
...  
Keyword(s):  
Castleman’S Disease ◽  
Lymphoid Hyperplasia ◽  
Reactive Lymphoid Hyperplasia ◽  
Castleman's Disease

scholarly journals Localized Castleman’s Disease in the Breast in a Young Woman

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Rafael Parra-Medina ◽  
José Ismael Guio ◽  
Patricia López-Correa
Keyword(s):  
Lymphoproliferative Disorder ◽  
Histopathological Examination ◽  
Castleman’S Disease ◽  
Unknown Etiology ◽  
Castleman's Disease ◽  
Axillary Lymphadenopathy ◽  
The Right ◽  
Slow Growing ◽  
Hyaline Vascular Variant

Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.

scholarly journals Role of Fine needle aspiration cytology in the diagnosis of Cervical lymphadenopathy

1970 ◽  
Vol 14 (2) ◽  
pp. 63-65 ◽  
Author(s):  
Md Arif Hossain Bhuiyan ◽  
Md Abu Yusuf Fakir ◽  
ABM Tofazzal Hossain ◽  
AHM Zahurul Huq ◽  
Sanjeev Gupta
Keyword(s):  
Frozen Section ◽  
Castleman’S Disease ◽  
Cervical Lymphadenopathy ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Lymphoid Hyperplasia ◽  
Lymph Node Biopsy ◽  
Castleman's Disease ◽  
Needle Aspiration Cytology ◽  
Set Up

Objective: A study was carried out to know the overall prevalence of various causes responsible for cervical lymphadenopathy of more than 3 weeks duration. FNAC has been evaluated as a diagnostic tool in our clinical set up. We aimed to present 110 cases which we treated in our center within last 3½ years. Methods: A retrospective study has been carried out from June 2005 to December 2008 in the department of Otolaryngology and Head-Neck Surgery at Apollo Hospitals Dhaka. All patients presented with cervical lymphadenopathy of more than 3 weeks duration. FNAC has been done for all suspected cases. CT neck has been done in 4 cases for deep jugular nodes. 55 patients underwent biopsy as FNAC report was non-specific lymphadenitis. For three cases we have done frozen section biopsy. Preoperative workup with routine blood tests, Xray chest and tuberculin tests have been carried out for all cases. Results: Out of 110 FNAC of cervical lymphadenopathy - 55 were non-specific lymphadenitis, 32 were tuberculosis, 12 were metastatic (with 2 occult primary), 6 were lymphomas(Immunocytochemistry proved ) and 5 were abscess. All 55 non-specific lymphadenopathy cases (FNAC report) underwent lymph node biopsy.5 cases were consistent with tuberculosis , 1 was lymphoma and rest were reactive . For 3 cases frozen section biopsy have been done. One was consistent with granulomatous disease and two cases were diagnosed as lymphoid hyperplasia. Both the lymphoid hyperplasia cases have been diagnosed as Castleman's disease after histopathology report. Conclusion: The study concluded the fact that the non-specific infection is the most common cause of cervical lymphadenopathy followed by tuberculosis .Supplemented with routine laboratory investigations, FNAC give very important clue to the physicians among patients presented with cervical lymphadenopathy. Key Words: Lymphadenopathy, lymphoid hyperplasia, tuberculosis, lymphoma, castleman's disease.  DOI: 10.3329/bjo.v14i2.3283 Bangladesh J of Otorhinolaryngology 2008; 14(2) : 63-65

scholarly journals Mesenteric Castleman’s Disease: A Rare Cause of Mesenteric Masses: A Case Report and Literature Review

2020 ◽  
Vol 2 (2) ◽  
pp. 01-05
Author(s):  
Abbas AR Mohamed ◽  
Abdulsalam A Bin Hafiz
Keyword(s):  
Lymph Node ◽  
Iliac Fossa ◽  
Castleman’S Disease ◽  
Unknown Etiology ◽  
Castleman's Disease ◽  
Angiofollicular Lymph Node Hyperplasia ◽  
Left Iliac Fossa ◽  
Palpable Mass ◽  
Cell Variant ◽  
Lymph Node Hyperplasia

Castleman’s disease, also known as angiofollicular lymph node hyperplasia or giant lymph node hyperplasia, is a rare benign B-cell lymphoproliferative disorder of unknown etiology. We report a case of a 23-year old woman with mesenteric Castleman’s disease of plasma cell variant presented as a palpable mass in the left iliac fossa.

Castleman's Disease and Spinal Cord Compression: Case Report

Neurosurgery ◽  
2002 ◽  
Vol 50 (2) ◽  
pp. 399-403 ◽  
Author(s):  
Edward Kachur ◽  
Lee-Cyn Ang ◽  
Joseph F. Megyesi
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Castleman’S Disease ◽  
Healthy Woman ◽  
Cord Compression ◽  
Pathological Examination ◽  
Castleman's Disease ◽  
Thoracic Spinal Cord ◽  
Excellent Outcome ◽  
Spinal Epidural

ABSTRACT OBJECTIVE AND IMPORTANCE Castleman's disease is a rare lymphoproliferative disorder most often found in the mediastinum. Localized forms are usually benign, whereas multicentric forms may be aggressive . We report a patient with Castleman's disease who presented with spinal cord compression, and we review previously published cases of Castleman's disease involving the central nervous system. To our knowledge, this is only the second case of Castleman's disease presenting as a spinal epidural mass with cord compression. CLINICAL PRESENTATION A 44-year-old otherwise healthy woman presented acutely with difficulty walking. Examination revealed mild myelopathy in her legs. Magnetic resonance imaging revealed a posterior epidural mass compressing the thoracic spinal cord at T3–T5. INTERVENTION Thoracic laminectomy and gross total resection of the lesion were performed. Pathological examination of the lesion identified the hyaline-vascular type of Castleman's disease. The patient's symptoms resolved postoperatively. CONCLUSION Castleman's disease presenting as a spinal epidural mass lesion with cord compression is rare. Surgical treatment can result in an excellent outcome.

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