scholarly journals Role of Fine needle aspiration cytology in the diagnosis of Cervical lymphadenopathy

1970 ◽  
Vol 14 (2) ◽  
pp. 63-65 ◽  
Author(s):  
Md Arif Hossain Bhuiyan ◽  
Md Abu Yusuf Fakir ◽  
ABM Tofazzal Hossain ◽  
AHM Zahurul Huq ◽  
Sanjeev Gupta
Keyword(s):  
Frozen Section ◽  
Castleman’S Disease ◽  
Cervical Lymphadenopathy ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Lymphoid Hyperplasia ◽  
Lymph Node Biopsy ◽  
Castleman's Disease ◽  
Needle Aspiration Cytology ◽  
Set Up

Objective: A study was carried out to know the overall prevalence of various causes responsible for cervical lymphadenopathy of more than 3 weeks duration. FNAC has been evaluated as a diagnostic tool in our clinical set up. We aimed to present 110 cases which we treated in our center within last 3½ years. Methods: A retrospective study has been carried out from June 2005 to December 2008 in the department of Otolaryngology and Head-Neck Surgery at Apollo Hospitals Dhaka. All patients presented with cervical lymphadenopathy of more than 3 weeks duration. FNAC has been done for all suspected cases. CT neck has been done in 4 cases for deep jugular nodes. 55 patients underwent biopsy as FNAC report was non-specific lymphadenitis. For three cases we have done frozen section biopsy. Preoperative workup with routine blood tests, Xray chest and tuberculin tests have been carried out for all cases. Results: Out of 110 FNAC of cervical lymphadenopathy - 55 were non-specific lymphadenitis, 32 were tuberculosis, 12 were metastatic (with 2 occult primary), 6 were lymphomas(Immunocytochemistry proved ) and 5 were abscess. All 55 non-specific lymphadenopathy cases (FNAC report) underwent lymph node biopsy.5 cases were consistent with tuberculosis , 1 was lymphoma and rest were reactive . For 3 cases frozen section biopsy have been done. One was consistent with granulomatous disease and two cases were diagnosed as lymphoid hyperplasia. Both the lymphoid hyperplasia cases have been diagnosed as Castleman's disease after histopathology report. Conclusion: The study concluded the fact that the non-specific infection is the most common cause of cervical lymphadenopathy followed by tuberculosis .Supplemented with routine laboratory investigations, FNAC give very important clue to the physicians among patients presented with cervical lymphadenopathy. Key Words: Lymphadenopathy, lymphoid hyperplasia, tuberculosis, lymphoma, castleman's disease.  DOI: 10.3329/bjo.v14i2.3283 Bangladesh J of Otorhinolaryngology 2008; 14(2) : 63-65

scholarly journals Role of Fine needle aspiration cytology in the diagnosis of Cervical lymphadenopathy

1970 ◽  
Vol 11 (1) ◽  
pp. 25-27
Author(s):  
AH Kafi ◽  
HB Arif ◽  
AS Ruhul
Keyword(s):  
Lymph Node ◽  
Frozen Section ◽  
Cervical Lymphadenopathy ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Lymphoid Hyperplasia ◽  
Lymph Node Biopsy ◽  
College Hospital ◽  
Node Biopsy ◽  
Set Up

Objective: A study was carried out to know the overall prevalence of various causes responsible for cervical lymphadenopathy of more than 3 weeks duration. FNAC has been evaluated as a diagnostic tool in our clinical set up. We aimed to present 120 cases which we treated in our center within last 4 years. Methods: A retrospective study has been carried out from August 2007 to August 2011 in the department of Otolaryngology and Head-Neck Surgery at CMH Rangpur, Apollo Hospitals Dhaka And Ibn Sina Medical College Hospital Dhaka. All patients presented with cervical lymphadenopathy of more than 3 weeks duration. FNAC has been done for all suspected cases. CT neck has been done in 4 cases for deep jugular nodes. 60 patients underwent lymph node biopsy as FNAC report was non-specific lymphadenitis. For three cases we have done frozen section biopsy. Preoperative workup with routine blood tests, Xray chest and tuberculin tests have been carried out for all cases. Results: Out of 120 FNAC of cervical lymphadenopathy - 60 were non-specific lymphadenitis, 34 were tuberculosis, 13 were metastatic (with 2 occult primary), 7 were lymphomas (Immunocytochemistry proved ) and 6 were abscess. All 60 non-specific lymphadenopathy cases (FNAC report) underwent lymph node biopsy.5 cases were consistent with tuberculosis , 1 was lymphoma and rest were reactive . For 3 cases frozen section biopsy have been done. One was consistent with granulomatous disease and two cases were diagnosed as lymphoid hyperplasia. Both the lymphoid hyperplasia cases have been diagnosed as Castleman's disease after histopathology report. Conclusion: The study concluded the fact that the non-specific infection is the most common cause of cervical lymphadenopathy followed by tuberculosis .Supplemented with routine laboratory investigations, FNAC give very important clue to the physicians that can be routinely used in patients with cervical lymphadenopathy. DOI: http://dx.doi.org/10.3329/bjms.v11i1.9818 BJMS 2012; 11(1): 25-27

scholarly journals Unusual and rare case of generalised lymphadenopathy: Kimura’s disease

2018 ◽  
pp. bcr-2018-225020
Author(s):  
Judah Arul ◽  
Narayanasamy Senthil ◽  
Lakshmi Marappa
Keyword(s):  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Symptomatic Improvement ◽  
Lymph Node Biopsy ◽  
High Dose ◽  
Kimura’S Disease ◽  
Aspiration Cytology ◽  
Pet Ct ◽  
Needle Aspiration Cytology ◽  
Loss Of Appetite

We report a case of Kimura’s disease in a 65-year-old woman who presented with generalised itching, abdominal pain, facial puffiness, difficulty in swallowing and loss of appetite. She was found to have generalised lymphadenopathy and a fine-needle aspiration cytology initially done revealed ‘reactive lymphadenitis’ which was inconclusive. PET-CT done showed features suggestive of lymphoma. Hence, lymph node biopsy was done for confirmation and incidentally after immunohistochemistry staining it turned out to be Kimura’s disease. High-dose steroid therapy was started and patient showed dramatic clinical and symptomatic improvement. Kimura’s disease almost always presents as cervical lymphadenopathy and usually never causes compressive symptoms. Our patient presented with compressive symptoms and generalised lymphadenopathy which is a rarity.

scholarly journals Clinicopathological study of thyroid swellings

2020 ◽  
Vol 6 (5) ◽  
pp. 974
Author(s):  
Anchal Gupta ◽  
Padam Singh Jamwal
Keyword(s):  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Clinical Problem ◽  
Neck Surgery ◽  
Needle Aspiration ◽  
Functional Abnormality ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Diseases of the thyroid continue to be a common clinical problem having a prevalence rate of 4 to 7% in the general population.</p><p class="abstract"><strong>Methods:</strong> This retrospective study was conducted in the Department of ENT, Head and Neck Surgery, SMGS Hospital, Jammu from January 2018 to January 2020. A thorough history taking, meticulous clinical examination, routine hematological and biochemical investigations were done in all the patients. General examination of the patient was done and looked for thyroid functional abnormality followed by local examination was carried out to locate and identify the site of the swelling, shape, size and consistency of the thyroid swelling and clinical diagnosis was made. All thyroid swelling cases were subjected to fine needle aspiration cytology (FNAC). The type of thyroidectomy is based on the size and type of thyroid whether neoplastic or non-neoplastic. All the specimens were sent for histopathological examination.  </p><p class="abstract"><strong>Results:</strong> Out of 60 patients in the study, 56 were females and only 4 were males. The most common age group was 31 to 40 years seen in 24 (40%) patients. The most common presenting symptom was swelling in the neck seen in 58 (96.67%) patients. The most common diagnosis on FNAC was colloid goiter seen in 40 (66.67%) patients. The most common was benign nodular colloid goiter seen in 35 (58.33%) patients.</p><p class="abstract"><strong>Conclusions:</strong> Fine needle aspiration is a very useful and indispensible test in the diagnosis of thyroid lesions.</p>

scholarly journals A prospective clinico-pathological study of cervical lymphadenopathy

2017 ◽  
Vol 4 (12) ◽  
pp. 3967
Author(s):  
Narender N. R. ◽  
Yadagiri Rao J.
Keyword(s):  
Lymph Nodes ◽  
Prospective Observational Study ◽  
Primary Tumour ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Excision Biopsy ◽  
Medical Sciences ◽  
Aspiration Cytology ◽  
Needle Aspiration Cytology ◽  
Carcinoma Tongue

Background: Lymphadenopathy refers to one or more lymph nodes that are abnormal in size, consistency or number. There are various causes for lymphadenopathy which range from benign conditions to malignant either primary or secondary from draining primary tumour. Lymphadenopathy can be localised to a single group or generalised.Methods: Prospective observational study was performed for the patients attending outpatient department of general surgery at Kamineni academy of medical sciences, LB nagar Hyderabad, Telangana with complaints of enlarged or swollen lymph nodes in the neck. This study included 46 cases. In cases where fine needle aspiration cytology was inconclusive and there was need for excision biopsy, only these cases were included in the study. After biopsy lymph node was sent for gross and microscopic examination for expert opinion from department of pathology.Results: The present study includes 46 patients in a period of two years from 01-8-2015 to 31-7-2017. Of these case tuberculosis lymphadenopathy (n=25,54.3%) was the most common aetiology followed by nonspecific chronic lymphadenopathy (n=16,34.7%) followed by some relatively rare cases and unusual presentation Schwannoma, pleomorphic adenoma, Kikuchi disease, non-Hodgkin’s lymphoma and secondaries from carcinoma tongue (n=1,2.1%).Conclusions: In the present prospective study tubercular lymphadenopathy was the most common cause for cervical lymphadenopathy followed by chronic nonspecific lymphadenopathy. 

scholarly journals Clinical profile of cervical lymphadenopathy and to find diagnostic efficacy of fine-needle aspiration cytology, ultrasonography and histopathological examination

2020 ◽  
Vol 6 (3) ◽  
pp. 551
Author(s):  
Nitin Sharma ◽  
Maya Singh ◽  
Pritosh Sharma ◽  
Rahul Nahar ◽  
V. P. Goyal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Tuberculous Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Common Diagnosis ◽  
Granulomatous Lymphadenitis ◽  
Needle Aspiration Cytology

<p class="abstract"><strong>Background:</strong> Cervical lymphadenopathy is the sign of a disease process which involves lymph nodes that are anomalous in uniformity and dimensions. It is very vital to exercise fine-needle aspiration biopsy, histopathological investigation, and ultrasonography for the diagnosis of palpable lesions.</p><p class="abstract"><strong>Methods:</strong> This is a prospective study of 12-month duration from January 2018 to December 2018 in 61 patients presenting with cervical lymphadenopathy admitted in the ENT Department at Geetanjali Medical College and Hospital, Udaipur.  </p><p class="abstract"><strong>Results:</strong> In biopsy, most common diagnosis was chronic granulomatous lymphadenitis i.e. in 62.3% of the patients. As compared to biopsy, fine-needle aspiration cytology (FNAC) showed chronic granulomatous lymphadenitis in 46% of the patients, with overall sensitivity of 91.1%, and specificity of 60.0%. and accuracy of 88.5%. Whereas ultrasonography (USG) reported, 64% cervical lymphadenopathy in patients, with overall sensitivity came out to be 91.1%, specificity to be 40.0%, accuracy was 86.9%.</p><p class="abstract"><strong>Conclusions:</strong> Present study showed that biopsy is the gold standard procedure for diagnosis of cervical lymphadenopathy lesions followed by FNAC, USG. Tuberculous lymphadenitis was most common diagnosis made by the diagnostic modalities.</p>

scholarly journals P18: MULTIPLE DIAGNOSIS OR CONTINUUM OF DISEASE: MULTICENTRIC CASTLEMAN'S DISEASE

2016 ◽  
Vol 64 (3) ◽  
pp. 824.1-824
Author(s):  
S Datla ◽  
K Parker ◽  
L Robert ◽  
N Soloman
Keyword(s):  
Young Woman ◽  
Mental Status ◽  
Castleman’S Disease ◽  
Altered Mental Status ◽  
Lymph Node Biopsy ◽  
Digital Ulcers ◽  
Castleman's Disease ◽  
Multicentric Castleman’S Disease ◽  
Unclear Etiology ◽  
Multicentric Castleman's Disease

Purpose of StudyMulticentric Castleman's disease (MCD) is a rare lymphoproliferative disorder characterized by peripheral lymphadenopathy (LAD), hepatosplenomegaly(HSM), and B symptoms. It is associated with HIV and HHV8 infection.We report a case of young woman presented with B symptoms, workup suggestive of lupus but lymph node biopsy (BX) was consistent with MCD. Association of SLE with MCD is rare. We report this case to increase awareness of this potential diagnostic and therapeutic dilemma.Methods UsedPatient is a 27 yr old black woman presented with malaise, fevers, cough, weight loss, arthralgia, alopecia, numbness of extremities and Raynaud's phenomenon. Patient had skin tightness around the mouth, telangiectasia, digital ulcers, HSM, pitting edema, diffuse LAD and moderate pericardial effusion.Laboratory results consistent with hemolytic anemia with Hb 5.6 g/dl, direct coombs positive, elevated reticulocyte count, LDH and low haptoglobin. Initial RF, ANA, and all infectious work up including HIV were normal. She was transfused cautiously, with inconclusive LN and bone marrow Bx. Patient left hospital against medical advice.She presented two days later with altered mental status (AMS) and hypotension. CT head and Lumbar puncture were negative. Hypotension responded to fluids, but no response in AMS. Repeat ANA, AntiSSB, AntiSm, AntiRNP, and Antihistone antibodies were positive. Patient met diagnostic criteria for SLE and was subsequently treated for lupus cerebritis with pulse steroids, with moderate improvement in mental status. Repeat LNBX revealed reactive lymphadenitis with features of MCD, HHV8 negative. Patient was treated with IL-6 inhibitor Siltuximab, with significant improvement in mental status.Summary of ResultsMCD is a rare angiolymphoproliferative disorder of unclear etiology. Most cases occur in middle aged men and are associated with immunosuppression where as SLE is common in women of child bearing age. Reported cases of MCD in association with SLE are common in immunocompetent young women. Our patient is a young woman, HIV/HHV8 negative with good response to Siltuximab, favoring MCD.ConclusionsIt is unclear whether this finding of MCD and SLE represents an overlap or a pure association. However, this phenomenon needs further investigation.

Sign in / Sign up

Export Citation Format

Share Document