Chapter Specialized cognitive behavior therapy for treatment resistant obsessive compulsive disorder

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164311 ◽  
Author(s):  
Fabian Lenhard ◽  
Sarah Vigerland ◽  
Hedvig Engberg ◽  
Anna Hallberg ◽  
Hanna Thermaenius ◽  
...  

Author(s):  
Brandon M. Kitay ◽  
Michael H. Bloch

This chapter provides a summary of a landmark study on the management of obsessive-compulsive disorder (OCD) in adults. Is the combination of exposure and ritual prevention (a cognitive behavior therapy based intervention) along with clomipramine more efficacious than monotherapy with either treatment for OCD? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study interventions, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications for clinical management, and concludes with an exemplary clinical case applying the evidence.


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