scholarly journals Effects of Yucca Saponin and Konjak Flour on Lipid Metabolism of Rats Fed a High-fat Plus High-cholesterol Diet.

1998 ◽  
Vol 51 (4) ◽  
pp. 157-163 ◽  
Author(s):  
Nobuko TSUJIHARA ◽  
Yumiko TANI
Keyword(s):  
Lipid Metabolism ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
High Fat

The effect of cranberry consumption on lipid metabolism and inflammation in human apo A-I transgenic mice fed a high-fat and high-cholesterol diet

2020 ◽  
pp. 1-8
Author(s):  
Christian Caceres ◽  
Mi-Bo Kim ◽  
Minkyung Bae ◽  
Tho X. Pham ◽  
Yoojin Lee ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Lipid Metabolism ◽  
Soleus Muscle ◽  
Hdl Cholesterol ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
High Fat ◽  
Expression Of Genes ◽  
Hdl Metabolism

Abstract Lipid metabolism and inflammation contribute to CVD development. This study investigated whether the consumption of cranberries (CR; Vaccinium macrocarpon) can alter HDL metabolism and prevent inflammation in mice expressing human apo A-I transgene (hApoAITg), which have similar HDL profiles to those of humans. Male hApoAITg mice were fed a modified American Institute of Nutrition-93M high-fat/high-cholesterol diet (16 % fat, 0·25 % cholesterol, w/w; n 15) or the high-fat/high-cholesterol diet containing CR (5 % dried CR powder, w/w, n 16) for 8 weeks. There were no significant differences in body weight between the groups. Serum total cholesterol, non-HDL-cholesterol and TAG concentrations were significantly lower in the control than CR group with no significant differences in serum HDL-cholesterol and apoA-I. Mice fed CR showed significantly lower serum lecithin–cholesterol acyltransferase activity than the control. Liver weight and steatosis were not significantly different between the groups, but hepatic expression of genes involved in cholesterol metabolism was significantly lower in the CR group. In the epididymal white adipose tissue (eWAT), the CR group showed higher weights with decreased expression of genes for lipogenesis and fatty acid oxidation. The mRNA abundance of F4/80, a macrophage marker and the numbers of crown-like structures were less in the CR group. In the soleus muscle, the CR group also demonstrated higher expression of genes for fatty acid β-oxidation and mitochondrial biogenesis than those of the control. In conclusion, although CR consumption elicited minor effects on HDL metabolism, it prevented obesity-induced inflammation in eWAT with concomitant alterations in soleus muscle energy metabolism.

scholarly journals Effect of Tochu-Leaf Powder on Lipid Metabolism in Stroke-Prone SHR (SHRSP) Fed a High-Fat and High-Cholesterol Diet

1995 ◽  
Vol 36 (4) ◽  
pp. 512-512
Author(s):  
Hiroshi Ogawa ◽  
Masatsuna Tasaka ◽  
Sukanari Sasagawa
Keyword(s):  
Lipid Metabolism ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
High Fat ◽  
Leaf Powder

scholarly journals Lactic Fermented Soymilk Improves Hepatic Lipid Metabolism in Rats Fed a High Fat and High Cholesterol Diet

2013 ◽  
Vol 60 (2) ◽  
pp. 72-79 ◽  
Author(s):  
Rie Hirahata ◽  
Maki Kobayashi ◽  
Shintaro Egusa ◽  
Rie Sakakibara ◽  
Mitsuru Fukuda
Keyword(s):  
Lipid Metabolism ◽  
High Cholesterol Diet ◽  
Cholesterol Diet ◽  
High Cholesterol ◽  
High Fat ◽  
Hepatic Lipid Metabolism ◽  
Hepatic Lipid
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