scholarly journals Selenocysteine in Trypanosoma evansi: Identification of the Genes selb, selc, seld, pstk, seltryp and the Selenophosphate Synthetase Protein

2021 ◽  
Vol 60 ◽  
pp. 21-29
Author(s):  
Kaio Cesar Simiano Tavares ◽  
Maria Gabriela Casagrande Dambrós ◽  
André Saraiva Leão Antunes ◽  
Pietro Martin Danziato ◽  
Patricia Hermes Stoco ◽  
...  

Selenoproteins have been described in all three domains of life and their function has been mainly associated with oxidative stress defense. Canonical elements required for selenoprotein production have been identified in members of the kinetoplastid group supporting the existence of a complete selenocysteine synthesis pathway in these organisms. Currently, nothing is known regarding the selenocysteine pathway in Trypanosoma evansi. In this study, we identified the expression of the elements selB, selC, selD, PSTK and selTRYP at the mRNA level in T. evansi. All translated proteins (selD, PSTK, selTRYP and selB) have the domains predicted and higher identity with Trypanosoma brucei. gambiense. The selenophosphate synthetase protein was localized in the cytoplasm. Our results support the existence of an active selenocysteine pathway in T. evansi.

2009 ◽  
Vol 37 (14) ◽  
pp. 4812-4825 ◽  
Author(s):  
José F. da Silva Neto ◽  
Vânia S. Braz ◽  
Valéria C. S. Italiani ◽  
Marilis V. Marques

2011 ◽  
Vol 74 (10) ◽  
pp. 1959-1973 ◽  
Author(s):  
Mitra Mohammadi Bazargani ◽  
Elham Sarhadi ◽  
Ali-Akbar Shahnejat Bushehri ◽  
Andrea Matros ◽  
Hans-Peter Mock ◽  
...  

2007 ◽  
Vol 282 (33) ◽  
pp. 24407-24415 ◽  
Author(s):  
Mauro Salvi ◽  
Valentina Battaglia ◽  
Anna Maria Brunati ◽  
Nicoletta La Rocca ◽  
Elena Tibaldi ◽  
...  

2008 ◽  
Vol 27 (4) ◽  
pp. 970 ◽  
Author(s):  
Cheng-Run Wang ◽  
Xiao-Rong Wang ◽  
Yuan Tian ◽  
Hong-Xia Yu ◽  
Xue-Yuan Gu ◽  
...  

2015 ◽  
Vol 37 (5) ◽  
pp. 1081-1089
Author(s):  
Guochao Wu ◽  
Jintang Sun ◽  
Shanshan Yu ◽  
Quanchao Dong ◽  
Guoqiang Zhuang ◽  
...  

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