scholarly journals Formulation Development and Characterization of Diltiazem Pulsin Cap for Pulsatile Drug Delivery

2019 ◽  
Vol 9 (5) ◽  
pp. 97-113
Author(s):  
Alisha Ishrath ◽  
Venkataratnam Devadas ◽  
Mohammed Mazher Ahmed
Keyword(s):  
Drug Delivery ◽  
Formulation Development ◽  
Pulsatile Drug Delivery

Formulation, Development, and Evaluation of Floating Pulsatile Drug Delivery System of Atenolol

2013 ◽  
Vol 67 (3) ◽  
pp. 214-228 ◽  
Author(s):  
S. C. Jagdale ◽  
M. S. Sali ◽  
A. L. Barhate ◽  
B. S. Kuchekar ◽  
A. R. Chabukswar
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Formulation Development ◽  
Pulsatile Drug Delivery

Physicochemical characterization of naproxen microcrystals for colon specific pulsatile drug delivery designed using pulsincap technique

2019 ◽  
Vol 49 (5) ◽  
pp. 553-564 ◽  
Author(s):  
Rocky Thapaliya ◽  
Kailash Shrestha ◽  
Asmita Sharma ◽  
Neelam Dhakal ◽  
Pragya Manandhar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Physicochemical Characterization ◽  
Pulsatile Drug Delivery

scholarly journals Preparation and characterization of timed drug delivery system of sumatriptan using natural polymers

2018 ◽  
Vol 27 (1) ◽  
pp. 89-99
Author(s):  
Mina Shihab Al-anbagi ◽  
Nawal A. Rajab ◽  
Yehia I.Khalil
Keyword(s):  
Drug Delivery ◽  
Circadian Rhythm ◽  
Active Pharmaceutical Ingredient ◽  
Lag Time ◽  
Natural Polymers ◽  
The Press ◽  
Coated Tablet ◽  
Pulsatile Drug Delivery ◽  
Core Tablet

Pulsatile drug delivery systems are time-controlled dosage forms which are designed to release the active pharmaceutical ingredient after a predetermined lag time to synchronize the disease circadian rhythm. A migraine shows circadian rhythm with a marked increase in attacks between 6 a.m. and 8 a.m. Sumatriptan is a selective agonist at serotonin (5-Hydroxy tryptamine1  (5-HT1))receptors, is an effective treatment for acute migraine attacks. The aim of this work is to prepare time-controlled press-coated tablet with a lag time of 5.45 hrs. Six formulas of fast dissolving core tablets and three formulas of press-coated tablets were prepared by using direct compression method using different variables to prepare core tablets which include: different types and concentrations of superdisintegrants While different concentrations of natural and synthetic polymers were utilized in the preparation of press-coated tablets. The obtained results showed that formula  F4 of core tablet, which contained 25 mg of sumatriptan, 5% w/w sodium starch glycolate and avicel PH 102 as the diluent, was the selected formula that gave the fastest and complete release of sumatriptan. Also, formula C3 of the press-coated tablet, which contained pectin: EC100 mpa.s: HPMCK15M in concentration30mg: 10mg:160mg respectively, was selected as the best coating layer since it gave 5.45  hours lag time.

Design and characterization of hollow/porous floating beads of captopril for pulsatile drug delivery

2012 ◽  
Vol 6 (2) ◽  
pp. 137 ◽  
Author(s):  
AnandPanchakshari Gadad ◽  
AnnapureddyDasaratharami Reddy ◽  
PanchaxariMallappa Dandagi ◽  
VinayakS Masthiholimath
Keyword(s):  
Drug Delivery ◽  
Pulsatile Drug Delivery
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