scholarly journals Analytical Method Development and Validation for The Estimation of Pioglitazone Hydrochloride in Bulk and Formulation by UV-Spectrophotometry

2020 ◽  
Vol 10 (03) ◽  
pp. 102-110
Author(s):  
K. Bhavyasri ◽  
R. Sai Chandana ◽  
M. Sumakanth ◽  
R. Swethasri
2021 ◽  
Vol 11 (6) ◽  
pp. 86-91
Author(s):  
Sachin N. Kapase

For qualitative and quantitative analysis, various analytical techniques are available such as Ultraviolet (UV) Spectrophotometry, High-performance liquid chromatography (HPLC), High-performance thin layer chromatography (HPTLC). As per literature survey, there are some UV, HPLC, Ultra-Performance Liquid Chromatography (UPLC) and HPTLC analytical methods are developed for Montelukast and Doxofylline individually and in a combination with other drugs too, since yet there are no significant stability studies indicating HPLC method reported for Montelukast and Doxofylline combinations. In the current study, the HPLC method is developed and validated for simultaneous quantitative estimations of Montelukast and Doxofylline. These present techniques are more efficient and sensitive as compared to other analytical techniques.


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