scholarly journals Plasma microRNA profiling highlights miR-1260b and miR-720 as novel diagnostic and prognostic biomarkers of esophageal squamous cell carcinoma

2021 ◽  
Vol 5 (2) ◽  
pp. 128-134
Author(s):  
Fuhua Wang ◽  
◽  
Yunfeng Yang ◽  
Xiangyun Guo ◽  
Feng Li ◽  
...  
2019 ◽  
Vol 15 ◽  
Author(s):  
Mohammadreza Mirinezhad ◽  
Narjes Khalilipour ◽  
Reza Raoofian ◽  
Mohammad Reza Abbaszadegan

The article has been withdrawn at the request of the editor of the journal Current Cancer Therapy Reviews (CCTR). Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused. BENTHAM SCIENCE DISCLAIMER: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.


Oncotarget ◽  
2016 ◽  
Vol 7 (38) ◽  
pp. 62034-62048 ◽  
Author(s):  
Shuhei Komatsu ◽  
Daisuke Ichikawa ◽  
Tsutomu Kawaguchi ◽  
Hiroki Takeshita ◽  
Mahito Miyamae ◽  
...  

2017 ◽  
Vol 15 (6) ◽  
pp. 3833-3839 ◽  
Author(s):  
Yan Wang ◽  
Jinnan Zhang ◽  
Wei Zhao ◽  
Donglin Wang ◽  
Wenduan Ma ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-2 ◽  
Author(s):  
Shuling Dong ◽  
Huiqing Yin ◽  
Cuicui Dong ◽  
Kaiyan Sun ◽  
Pin Lv ◽  
...  

2020 ◽  
Vol Volume 12 ◽  
pp. 9753-9763
Author(s):  
Suzhen Yan ◽  
Lutao Du ◽  
Xiumei Jiang ◽  
Weili Duan ◽  
Juan Li ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Shuling Dong ◽  
Huiqing Yin ◽  
Cuicui Dong ◽  
Kaiyan Sun ◽  
Pin Lv ◽  
...  

Esophageal squamous cell carcinoma (ESCC) is a common human malignancy with poor survival, which was usually diagnosed at an advanced stage. MicroRNAs (miRNAs), a class of single stranded noncoding RNAs with only 17–25 ribonucleotides, were demonstrated to play an important role in lots of cancers. In the recent years, increasing evidence revealed that circulating miRNAs exhibited great potential in the diagnosis of various types of cancers. The present study was designed to evaluate the diagnostic value of plasma miRNA-216a/b for ESCC. Our results showed that the expression level of plasma miRNA-216a/b was significantly lower in ESCC patients compared with that of healthy controls. The receiver operating characteristic (ROC) curve analysis yielded an area under the ROC curve (AUC) value of 0.877 [95% CI (confidence interval): 0.818–0.922] for miRNA-216a and 0.756 (95% CI: 0.685–0.819) for miRNA-216b. Clinical data indicated that plasma miRNA-216a/b were inversely correlated with lymph node metastasis and TNM stage. Additionally, the plasma miRNA-216b expression level was significantly upregulated in postoperative samples compared to preoperative samples. Our study, for the first time, demonstrated that plasma miRNA-216a/b might serve as potential biomarkers for the diagnosis of ESCC and dysregulation of miRNA-216a/b might be involved in the progression of ESCC.


Sign in / Sign up

Export Citation Format

Share Document