scholarly journals CYCLIN D1: As a Risk of Breast Cancer

Author(s):  
Preeti Chauhan ◽  
Palki sahib Kaur ◽  
Arockia M Babu

Breast cancer is varying group of tumors in terms of disease prognosis. Breast cancer is found as second main cause of death related with cancer. Cyclin D1 (CCND1) is an important regulator of cell cycle. CCND1over expressed in various human cancers like head, oesophageal, neck, squamous, colon, breast, prostateetc. Many studies have conducted to find correlation between polymorphism in CCND1 gene and development of breast cancer. Some studies found certain genotypes related with risk of breast cancer development. Some studies also proposed the role of varying genetic backgrounds in breast cancer development. This review focuses on role of CCND1 polymorphism and possible risk factors associated with breast cancer, which may explicate the breast cancer screening, prevention, and treatments strategies for future use.

2020 ◽  
Author(s):  
V. A. Kurnosova ◽  
V. N. Kipen ◽  
Zh. T. Isakova ◽  
К. А. Aitbaev ◽  
M. A. Usufova ◽  
...  

2018 ◽  
Vol 07 (01) ◽  
Author(s):  
Sm Faysal Bellah ◽  
Hameed Akbar ◽  
S M Saker Billah ◽  
Divine Mensah Sedzro

2011 ◽  
Author(s):  
Melissa Nicole Scheiber ◽  
Patricia M. Watson ◽  
Victoria J. Findlay ◽  
Tihana Rumboldt ◽  
Dennis K. Watson

2020 ◽  
Vol 26 (11) ◽  
pp. 2323-2326
Author(s):  
Shayan Mostafaei ◽  
Pegah Vahidi Manesh ◽  
Javid Sadri Nahand ◽  
Abolfazl Nesaei ◽  
Saba Sorayyayi ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1391
Author(s):  
Boyoung Park ◽  
Se-Eun Lim ◽  
HyoJin Ahn ◽  
Junghyun Yoon ◽  
Yun Su Choi

We evaluated the heterogeneity of the effect of known risk factors on breast cancer development based on breast density by using the Breast Imaging-Reporting and Data System (BI-RADS). In total, 4,898,880 women, aged 40–74 years, who participated in the national breast cancer screening program in 2009–2010 were followed up to December 2018. Increased age showed a heterogeneous association with breast cancer (1-year hazard ratio (HR) = 0.92, 1.00 (reference), 1.03, and 1.03 in women with BI-RADS density category 1, 2, 3, and 4, respectively; P-heterogeneity < 0.001). More advanced age at menopause increased breast cancer risk in all BI-RADS categories. This was more prominent in women with BI-RADS density category 1 but less prominent in women in other BI-RADS categories (P-heterogeneity = 0.009). In postmenopausal women, a family history of breast cancer, body mass index ≥ 25 kg/m2, and smoking showed a heterogeneous association with breast cancer across all BI-RADS categories. Other risk factors including age at menarche, menopause, hormone replacement therapy after menopause, oral contraceptive use, and alcohol consumption did not show a heterogeneous association with breast cancer across the BI-RADS categories. Several known risk factors of breast cancer had a heterogeneous effect on breast cancer development across breast density categories, especially in postmenopausal women.


2019 ◽  
Vol 10 (5) ◽  
pp. 1216
Author(s):  
Ala'a Abdul-Khaliq ◽  
Batool A. Al-Haidary ◽  
Nahida R. Abbas

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