scholarly journals Neutrophil to Lymphocyte Ratio in Patients with End Stage Renal Disease in Benue State University Teaching Hospital, Makurdi, Nigeria

2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.

2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.


2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.


2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.


2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.


Entropy ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 114 ◽  
Author(s):  
Martín Calderón-Juárez ◽  
Gertrudis Hortensia González-Gómez ◽  
Juan C. Echeverría ◽  
Héctor Pérez-Grovas ◽  
Claudia Lerma

Linear heart rate variability (HRV) indices are dependent on the mean heart rate, which has been demonstrated in different models (from sinoatrial cells to humans). The association between nonlinear HRV indices, including those provided by recurrence plot quantitative analysis (RQA), and the mean heart rate (or the mean cardiac period, also called meanNN) has been scarcely studied. For this purpose, we analyzed RQA indices of five minute-long HRV time series obtained in the supine position and during active standing from 30 healthy subjects and 29 end-stage renal disease (ESRD) patients (before and after hemodialysis). In the supine position, ESRD patients showed shorter meanNN (i.e., faster heart rate) and decreased variability compared to healthy subjects. The healthy subjects responded to active standing by shortening the meanNN and decreasing HRV indices to reach similar values of ESRD patients. Bivariate correlations between all RQA indices and meanNN were significant in healthy subjects and ESRD after hemodialysis and for most RQA indices in ESRD patients before hemodialysis. Multiple linear regression analyses showed that RQA indices were also dependent on the position and the ESRD condition. Then, future studies should consider the association among RQA indices, meanNN, and these other factors for a correct interpretation of HRV.


2013 ◽  
Vol 46 (4) ◽  
pp. 426-432 ◽  
Author(s):  
Tamara Trelha Gauna ◽  
Elizete Oshiro ◽  
Yuri Correa Luzio ◽  
Anamaria Mello Miranda Paniago ◽  
Elenir Rose Jardim Cury Pontes ◽  
...  

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Muhammad Nadeem ◽  
Mansoor Abbas Qaisar ◽  
Ali Hassan Al Hakami ◽  
Fateh Sher Chattah ◽  
Muhammad Muzammil ◽  
...  

Background: The mean arterial pressure serves as an expression of blood pressure in patients on chronic hemodialysis. Serum calcium phosphorus product is considered as a risk factor of vascular calcification that is associated with hypertension in the patients of end stage renal disease. The literature regarding this relationship is inconsistent therefore this study is designed to determine the correlation between calcium phosphorus product and mean arterial pressure among hemodialysis patients with end stage renal disease. Methods: A total of 110 patients of end stage renal disease on hemodialysis for at least one year, 20 to 60 years of age were included. Patients with primary or tertiary hyperparathyroidism, peripheral vascular disease, malignancy, hypertension secondary to any cause other than kidney disease were excluded. Mean arterial pressure was calculated according to the standard protocol in lying position. Blood samples for estimation of serum calcium and phosphorous were taken and was sent immediately to the laboratory for serum analysis. Results: Mean age was 44.17 ± 10.94 years. Mean calcium phosphorous product was 46.71 ± 7.36 mg/dl and mean arterial pressure was 103.61 ± 12.77 mmHg. The values of Pearson correlation co-efficient (r) were 0.863 for age group 20 to 40 years and 0.589 for age group 41 to 60 years. This strong positive correlation means that high calcium phosphorous product goes with high mean arterial pressure (and vice versa) for both the age groups. Conclusion: A strong positive relationship exists between the mean arterial pressure and calcium phosphorous product and is independent of patients’ age.


Sign in / Sign up

Export Citation Format

Share Document