scholarly journals Association between Mean Heart Rate and Recurrence Quantification Analysis of Heart Rate Variability in End-Stage Renal Disease

Entropy ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 114 ◽  
Author(s):  
Martín Calderón-Juárez ◽  
Gertrudis Hortensia González-Gómez ◽  
Juan C. Echeverría ◽  
Héctor Pérez-Grovas ◽  
Claudia Lerma
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Healthy Subjects ◽  
The Mean ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients ◽  
Mean Heart Rate

Linear heart rate variability (HRV) indices are dependent on the mean heart rate, which has been demonstrated in different models (from sinoatrial cells to humans). The association between nonlinear HRV indices, including those provided by recurrence plot quantitative analysis (RQA), and the mean heart rate (or the mean cardiac period, also called meanNN) has been scarcely studied. For this purpose, we analyzed RQA indices of five minute-long HRV time series obtained in the supine position and during active standing from 30 healthy subjects and 29 end-stage renal disease (ESRD) patients (before and after hemodialysis). In the supine position, ESRD patients showed shorter meanNN (i.e., faster heart rate) and decreased variability compared to healthy subjects. The healthy subjects responded to active standing by shortening the meanNN and decreasing HRV indices to reach similar values of ESRD patients. Bivariate correlations between all RQA indices and meanNN were significant in healthy subjects and ESRD after hemodialysis and for most RQA indices in ESRD patients before hemodialysis. Multiple linear regression analyses showed that RQA indices were also dependent on the position and the ESRD condition. Then, future studies should consider the association among RQA indices, meanNN, and these other factors for a correct interpretation of HRV.

scholarly journals Dynamical interaction between heart rate and blood pressure of end-stage renal disease patients evaluated by cross recurrence plot diagonal analysis

2020 ◽  
Vol 128 (1) ◽  
pp. 189-196 ◽  
Author(s):  
G. Hortensia González ◽  
Oscar Infante ◽  
Paola Martínez-García ◽  
Héctor Pérez-Grovas ◽  
Nadia Saavedra ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Renal Disease ◽  
Systolic Blood Pressure ◽  
End Stage Renal Disease ◽  
Recurrence Plots ◽  
Interbeat Interval ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

The assessment of spontaneous variability of blood pressure and heart rate is based on specific physiological hypotheses about dynamic features, for example, the baroreflex modulation of heart rate over time in daily life. Usually, arterial baroreflex control of heart rate is explored without delays between blood pressure and heart rate data points, within a narrow range of values, excluding the analysis of saturation regions or low-threshold changes. In this work, we examine the dynamic interactions between systolic blood pressure (SBP) and interbeat interval (IBI), in 15-min length time series and for the first time using the analysis of diagonals derived from a cross-recurrence plots in healthy persons and end-stage renal disease (ESRD) patients. We found that ESRD patients have stronger intermittent dynamical interactions between IBI and SBP, but they lose most of the dynamical interactions. Although healthy subjects exhibit a continuously changing order of precedence between IBI and SBP at different lags, ESRD patients preserve this changing order of precedence only for lags >0 beats. NEW & NOTEWORTHY This study is the first to compare the time-variant pattern of systolic blood pressure (SBP) and interbeat interval (IBI) coupling between ESRD patients and healthy volunteers through the analysis of diagonal in cross-recurrence plots, and in the face of an orthostatic challenge. Our results demonstrated alternant interactions on the order of precedence (IBI → SBP or SBP→ IBI) at different time delays. This pattern is different in resting position and during active standing for the two groups studied, and interestingly, some association patterns are lost in ESRD patients. These patterns of alternant interactions on the order of precedence could be related to autonomic neural activities and cardiovascular synchronization at different scales both in time and space. This could reflect physiological adaptive flexibility of cardiovascular regulation. Losing some association patterns in ESRD may be the result of chronic adjustments of many physiological mechanisms (including chronic sympathetic hyperactivity), which could increase cardiovascular vulnerability to hemodynamic challenges.

Heart Rate Variability, Mortality, and Exercise in Patients with End-Stage Renal Disease

2000 ◽  
Vol 10 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Ann K. Cashion ◽  
Patricia A. Cowan ◽  
E. Jean Milstead ◽  
A. Osama Gaber ◽  
Donna K. Hathaway
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Kidney Transplantation ◽  
Renal Disease ◽  
Mortality Risk ◽  
End Stage Renal Disease ◽  
Autonomic Function ◽  
Cardiac Autonomic Function ◽  
Stage Renal Disease ◽  
End Stage

Context Cardiac autonomic function has been associated with mortality in patients with end-stage renal disease. It is unknown whether end-stage renal disease patients who have succumbed to sudden cardiac death can be better identified by a newer test of heart rate variability that uses spectral analysis, rather than laboratory evoked measures. Objective This series of studies sought to characterize cardiac autonomic function in patients awaiting kidney transplantation, identify factors associated with heart rate variability, identify tests which distinguish patients at-risk for death, and compare evoked measures with 24-hour heart rate variability measures. Patients Data were collected on 184 nondiabetics, 60 type 1 diabetics, and 34 type 2 diabetics with end-stage renal disease, all of whom had been referred for kidney transplantation. Main Outcome Measures The 278 patients and 67 healthy control subjects underwent evoked tests (changes in heart rate with deep breathing and Valsalva maneuver) and 24-hour heart rate variability Holter monitoring (time and frequency domains). Five patients had sudden cardiac deaths during the study. Results Data showed that end-stage renal disease patients, particularly diabetics, had compromised autonomic function. The standard deviation of all R-to-R intervals for the electrocardiogram recording (<50 minutes in 60% of the deceased patients), a 24-hour heart rate variability time domain measure, holds the promise of identifying patients at increased risk for death. Exercise was identified as a factor associated with better autonomic function. Examining relationships between 24-hour heart rate variability and characteristics of patients who succumb to death could make quantification of the mortality risk for individual pretransplant end-stage renal disease patients possible, much as it has in other populations. The data from this study may also make it possible to design interventions, such as exercise, aimed at reducing mortality risk.

scholarly journals The effect of on-line hemodiafiltration on heart rate variability in end-stage renal disease

2013 ◽  
Vol 32 (3) ◽  
pp. 127-133 ◽  
Author(s):  
Kyung Won Park ◽  
Sang Kyun Bae ◽  
Buhyun Lee ◽  
Jeong Hun Baek ◽  
Jin Woo Park ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
On Line ◽  
Stage Renal Disease ◽  
End Stage

Heart rate variability, mortality, and exercise in patients with end-stage renal disease

2000 ◽  
Vol 10 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Ann Cashion ◽  
Patricia Cowan ◽  
E. Milstead ◽  
A. Gaber ◽  
Donna Hathaway
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Neutrophil to Lymphocyte Ratio in Patients with End Stage Renal Disease in Benue State University Teaching Hospital, Makurdi, Nigeria

2020 ◽  
Vol 3 (1) ◽  
pp. 250-255
Author(s):  
MO Ogiator ◽  
JE Ojobi ◽  
OO Ijachi
Keyword(s):  
Renal Disease ◽  
Systemic Inflammation ◽  
Teaching Hospital ◽  
End Stage Renal Disease ◽  
Healthy Subjects ◽  
University Teaching ◽  
State University ◽  
The Mean ◽  
Stage Renal Disease ◽  
End Stage

Chronic Kidney Disease (CKD) leads to end-stage renal disease (ESRD) and cardiovascular events. An important determinant of progression in CKD is chronic systemic inflammation which can be evaluated using the neutrophil to lymphocyte ratio (NLR). We aimed to investigate the value of NLR in patients with ESRD compared with healthy subjects. This was a retrospective study that analyzed data from patients with end-stage renal disease and equal number of age and sex matched control (healthy subjects) seen at Benue State University Teaching Hospital Makurdi from October 1st, 2012 to 31st December 2015. Out of the 118 patients studied 70(59.3) were males while 48 (40.7) were females. The mean age of the study population was 45.9 ± 16.4. The mean NLR for patients with ESRD was 3.55± 4.01 while that of healthy subjects was 1.29± 0.25. The mean NLR for patients was 3.47±4.01 for males and 3.68±4.06 for females while for the healthy subjects the mean NLR was 1.30±0.27 for males 1.27±0.22 for females. This study revealed elevated NLR in patients with ESRD. NLR reflects systemic inflammation. The availability of this ratio (NLR) can help improve outcome of patients with CKD.

THE RELATIONSHIP BETWEEN WEEKLY CLEARANCE OF UREA AND CREATININE IN END-STAGE RENAL DISEASE PATIENTS TREATED WITH CONTINUOUS AMBULATORY PERITONEAL DIALYSIS

2013 ◽  
pp. 74-80
Author(s):  
Viet Thang Hoang
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Acid Base Balance ◽  
Waste Products ◽  
Base Balance ◽  
The Mean ◽  
Stage Renal Disease ◽  
End Stage ◽  
The Relationship ◽  
Esrd Patients

Backgrounds: The aims dialysis of any sort include maintenance of normal body fluid status, normal electrolyte and acid-base balance, and removal of waste products. The degree of adequacy of removing nitrogenous waste products is very important. So the aims of this study: calculating Kt/Vurea and CCr in end-stage renal disease patients treated by CAPD and evaluating the correlation between clearance of urea and creatinine. Patients-Methods: 30 ESRD patients treated by CAPD at Department of Nephrology- Hue central Hospital were selected for this study from 1/2010 to 6/2011. The design of the study was a prospective crossover design. Results: The mean age of the patients was: 36,17±10,74 years(male) and 49,07 ± 12,75 years (female). Weekly Kt/Vure/t at T0: 2,43 ± 0,86 and T9: 2,26 ± 0,75; Weekly CCr at T0: 95,45 ± 29,39 L/week/1,73 m2 and T9: 90,81 ± 27,44 L/week/l,73 m2, p > 0,05. There was a positive-relation between Kt/Vure/week) and (CCr/week), (r = 0,638; p < 0,05).

Outcomes of Simultaneous Peritoneal Dialysis and Arteriovenous Fistula Placement in End-Stage Renal Disease Patients

2017 ◽  
Vol 37 (6) ◽  
pp. 658-661 ◽  
Author(s):  
Nosratollah Nezakatgoo ◽  
Albert Ndzengue ◽  
Manhunath Ramaiah ◽  
Elvira O. Gosmanova
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Disease ◽  
Arteriovenous Fistula ◽  
End Stage Renal Disease ◽  
Catheter Insertion ◽  
The Mean ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Peritoneal dialysis (PD) interruption requiring hemodialysis (HD) is not uncommon and its frequently abrupt nature prevents timely creation of permanent HD access and avoidance of central venous catheters (CVC). We retrospectively studied a cohort of 24 end-stage renal disease (ESRD) patients (mean age 50.7 years, 83.3% African-Americans, 58.3% females, time on dialysis interquartile range [IQR] 0 - 65 days) who had simultaneous PD catheter insertion and backup arteriovenous fistula (AVF) creation between January 1, 2012, and December 31, 2013. The primary outcome of interest was the percent of patients receiving HD through the backup AVF at the time of PD interruption. A median (IQR) for PD catheter use after its insertion was 10.5 (2 - 20) days. After the mean follow-up of 19.6 months, 12 patients remained on PD, 2 patients received a kidney transplant, and 1 patient died. The overall AVF patency was 66.7%. A total of 9 (37.5%) patients had PD interruption requiring permanent (8 patients) or temporary (1 patient) HD after the mean (standard deviation [SD]) follow-up of 12.3 (8.2) months. Arteriovenous fistula was used as the initial access in 4 patients, and in 3 patients the original AVF was used after additional surgical revision. Forty-four percent of patients with a backup AVF fistula avoided CVC at the time of PD interruption requiring HD. The simultaneous AVF creation at the time of PD catheter insertion reduced but did not fully eliminate CVC at the time of PD interruption. Larger studies are needed to evaluate the utility of a backup AVF in PD patients.

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