Gates Foundation and Exscientia to develop pandemic antivirals

2021 ◽  
pp. 15-15
Author(s):  
Megha Satyanarayana
Keyword(s):  
Mousaion ◽  
2020 ◽  
Vol 38 (3) ◽  
Author(s):  
Harry Ramothupi Matolong

Statistics and numerous authors have highlighted the reading crisis in South Africa. At the same instance, more people in South Africa are embracing the potential of digital technology to provide lifelong learning opportunities and also to strengthen the culture of reading. This study is framed against the backdrop and implementation of the Mzansi Libraries On-Line Project in South Africa – a project implemented in line with the Global Libraries Programme of the Bill & Melinda Gates Foundation. The study explored the potential of access to information of digital technology and the contribution of the project to inculcating a culture of reading at public libraries. A benchmark survey was conducted by an independent research company during the pilot phase of the project in 2015. This survey covered library users of the 27 libraries that formed part of the pilot phase, and a further 25 libraries from a representative sample across South Africa. An end-line survey was conducted through a private company towards the conclusion of the countrywide implementation in 2017, based on the Common Impact Measurement System which was customised for South Africa. The benchmark survey found that although ICT in libraries had been used by relatively few people in 2015, the impact of this technology tended to be positive and would be beneficial to the wider society by helping to redress societal imbalances, including education and the culture of reading. The end-line survey found increased benefits of library usage and library technical infrastructure to improve the lives of the communities involved.


2015 ◽  
Vol 10 (4) ◽  
pp. 141-142
Author(s):  
Carrie Arnold
Keyword(s):  

2021 ◽  
Vol 99 (8) ◽  
pp. 11-11
Author(s):  
Melody M. Bomgardner

Surgery ◽  
2019 ◽  
Vol 165 (2) ◽  
pp. 273-280 ◽  
Author(s):  
Rachel Koch ◽  
Lina Roa ◽  
Jordan Pyda ◽  
Monica Kerrigan ◽  
Ernest Barthélemy ◽  
...  

2019 ◽  
Author(s):  
Damian Pattinson

In recent years, funders have increased their support for early sharing of biomedical research through the use of preprints. For most, such as the COAlitionS group of funders (ASAPbio 2019) and the Gates foundation, this takes the form of active encouragement, while for others, it is mandated. But despite these motivations, few authors are routinely depositing their work as a preprint before submitting to a journal. Some journals have started offering authors the option of posting their work early at the point at which it is submitted for review. These include PLOS, who offer a link to BiorXiv, the Cell journals, who offer SSRN posting through ‘Sneak Peak’, and Nature Communications, who offer posting to any preprint and a link from the journal page called ‘Under Consideration’. Uptake has ranged from 3% for the Nature pilot, to 18% for PLOS (The Official Plos Blog 2018). In order to encourage more researchers to post their work early, we have been offering authors who submit to BMC Series titles the opportunity to post their work as a preprint on Research Square, a new platform that lets authors share and improve their research. To encourage participation, authors are offered a greater amount of control and transparency over the peer review process if they opt in. First, they are given a detailed peer review timeline which updates in real time every time an event occurs on their manuscript (reviewer invited, reviewer accepts etc). Second, they are encouraged to share their preprint with colleagues, who are able to post comments on the paper. These comments are sent to the editor when they are making their decision. Third, authors can suggest potential peer reviewers, recommendations which are also passed onto the editor to vet and invite. Together, these incentives have had a positive impact on authors choosing to post a preprint. Among the journals that offer this service, the average opt-in rate is 40%. This translates to over 3,000 manuscripts (as of July 2019) that have been posted to Research Square since the launch of the service in October 2018. In this talk I will demonstrate the functionality of Research Square, and provide demographic and discipline data on which areas are most and least likely to post.


2021 ◽  
Author(s):  
Javier Perez-Saez ◽  
Justin Lessler ◽  
Elizabeth C. Lee ◽  
Francisco J. Luquero ◽  
Espoir B. Malembaka ◽  
...  

Background Cholera remains a major threat in Sub-Saharan Africa (SSA) where some of the highest case fatality risks are reported. Knowing in what months and where cholera tends to occur across the continent can aid in improving efforts to eliminate cholera as a public health concern; though largely due to lack of unified large-scale datasets, no continent-wide estimates exist. In this study we aim to estimate cholera seasonality across SSA. Methods We leverage the Global Task Force on Cholera Control (GTFCC) global cholera database with statistical models to synthesize data across spatial and temporal scale in order to infer the seasonality of excess suspected cholera occurrence in SSA. We developed a Bayesian statistical model to infer the monthly risk of excess cholera at the first and/or second administrative levels. Seasonality patterns were then grouped into spatial clusters. Finally, we studied the association between seasonality estimates and hydro-climatic variables. Findings The majority of studied countries (24/34) have seasonal patterns in excess cholera, corresponding to approximately 85% of the SSA population. Most countries (19/24) also had sub-national differences in seasonality patterns, with strong differences in seasonality strength between regions. Seasonality patterns clustered into two macro-regions (West Africa and the Sahel vs. Eastern and Southern Africa), which were composed of sub-regional clusters with varying degrees of seasonality. Exploratory association analysis found most consistent and positive correlations between cholera seasonality and precipitation, and to a lesser extent with temperature and flooding. Interpretation Widespread cholera seasonality in SSA offers opportunities for intervention planning. Further studies are needed to study the association between cholera and climate. Funding The NASA Applied Sciences Program and the Bill and Melinda Gates Foundation.


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