scholarly journals The Effects of Space Radiation on Small Satellites-General Structure of Cubesat and Internet of Space Things

2021 ◽  
Vol 5 (2) ◽  
pp. 230-240
Author(s):  
Merve ALTUNAY ◽  
Mustafa AKKAŞ ◽  
Özge GÖY
1996 ◽  
Vol 76 (05) ◽  
pp. 697-702 ◽  
Author(s):  
Olivier Taby ◽  
Claire-Lise Rosenfield ◽  
Vladimir Bogdanov ◽  
Yale Nemerson ◽  
Mark B Taubman

SummaryTissue factor (TF) initiates coagulation and its expression in vascular smooth muscle cells (VSMC) likely plays a role in the propagation of arterial thrombosis. We report cloning the cDNA and proximal promoter region of the rat TF gene. While maintaining the general structure and organization of the TF molecule, there is a surprising divergence (≈ 18%) between the derived amino acid sequences of the rat and mouse TF. In contrast, there is striking similarity (90%) in the 5’ untranslated regions. High levels of basal promoter activity were seen in rat VSMC with constructs containing 106 bp of sequence downstream from the putative transcription start site and 426 to 103 bp of upstream sequence. Deletion of the sequence from −103 to −79, containing a single SP1 site, removed virtually all of the basal and serum-induced activity. Removal of the NFkB site or two additional upstream SP1 sites had little effect on serum responsiveness. Removal of the 5’ untranslated region abolished most of the basal activity of the TF promoter, suggesting that its high degree of conservation may be due to the presence of transcriptional elements critical for TF expression in rodent VSMC.


2009 ◽  
Author(s):  
H. Helvajian ◽  
S. Janson
Keyword(s):  

2000 ◽  
Author(s):  
P. Freeborn ◽  
G. Stamerjohanns ◽  
M. Kinnersley
Keyword(s):  

2017 ◽  
Vol 17 (6) ◽  
pp. 41-46
Author(s):  
V.V. Aksenov ◽  
◽  
I.V. Chicherin ◽  

2020 ◽  
Vol 11 (1) ◽  
pp. 78-82
Author(s):  
Toni Manasieva ◽  

The article presents an example model of a seminar on the topic of the connection between three phenomena: poverty, deviant behavior, social exclusion. Taking into account the general parameters valid for the whole community, the attention is focused on the specific dimensions in children. The general structure follows the logic: from the identification of the problem in its essence, through its causal connection, to the approaches to dealing with it. The possibilities and limitations in principle and in individual cases that affect the analysis and methodological decisions are taken into account – e.g. some popular stereotypes and prejudices. The model can be used both in the form of the above – in the training of students – future specialists in pedagogy and social activities, as well as for work with current specialists in practice.


Author(s):  
Olga Vyacheslavovna Zhukova ◽  
Ekaterina Sergeevna Nekaeva ◽  
Elena Sergeevna Khoroshavina ◽  
Ekaterina Alexeevna Kozlova ◽  
Yulia Alexandrovna Dudukina ◽  
...  

Objective: to conduct pharmacoepidemiological analysis and analysis of the costs of pharmacotherapy, taking into account the actual consumption of drugs in the real inpatient clinical practice at the federal center in Russia. Materials and methods. Data from the medical records of 14 patients with burn injury, who were hospitalized in 2018, was analyzed. Patients’ age was from 23 to 67 years (44,93 ± 14,66). Duration of hospitalization was from 17 to 62 days (35,93 ± 14,17). We calculated rate of prescription foe each drug and its share in general structure of all utilized drug courses (n = 460). We performed frequency analysis of prescription structure, DDD (defined daily doses) analysis, DU90% (Drug Utilization 90%) analysis, ABC-analysis and analysis of average cost of pharmacotherapy. Results. Most frequently used drugs, prescribed in 75-100% of all hospital cases, included 15 names, e.g. 2 antimicrobial drugs (vancomycin and amikacin), 19 were used commonly, including 4 antimicrobial drugs (co-trimoxazole, cefoperazone/sulbactam, tigecyclin and cefepime). Other drugs were used in less than 25% of cases. 33 drugs made 90% of all consumed NDDD, including 5 antimicrobial drugs (vancomycin, amikacin, co-trimoxazole, cefoperazone/sulbactam and tigecyclin). These drugs comprised 70,24% in the prescription structure. The cost of one DDD in DU90% segments (512,33 rubles) is 1,4 higher than in DU10% segment (649,34 rubles). Average cost of drugs included in DU90% group was 4735,89 rubles vs 4966,80 rubles for drugs from DU10% group. This finding shows positive tendency of burn injuries pharmacological treatment. Conclusion. We obtained the data, which can be used for comparison of real clinical practice costs with a current payment rates for medical care.


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