scholarly journals Polymorphous Low-grade Adenocarcinoma of the Palate: Report of a Case and Review of Literature

2011 ◽  
Vol 2 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Siddharth Gupta ◽  
C Anand Kumar ◽  
Namita Raghav

ABSTRACT Polymorphous low-grade adenocarcinoma (PLGA) is a malignancy arising predominantly from minor salivary glands. PLGAs account for 10% of all tumors and 25% of all malignancies of the minor salivary glands. It has been frequently described as occurring in hard or soft palate minor salivary glands; some cases being described in the tongue and in major salivary glands. We report a case of PLGA of the palate extending into the maxillary sinus and nasal cavity diagnosed on the basis of histopathology and treated by subtotal maxillectomy. The review of literature concerning clinical, histological and immunohistochemical features, as well as the proper management concerning this tumor is included.

2015 ◽  
Vol 6 (1) ◽  
pp. 23-25
Author(s):  
Santosh Kumar Swain ◽  
Mahesh Chandra Sahu ◽  
Rajashree Tripathy

ABSTRACT Pleomorphic adenoma (PA) is the most common benign tumor of the salivary glands and has both epithelial and mesenchymal tissues. It most commonly arises from the parotid or submandibular glands. Rarely, it arises from the minor salivary glands. We report here a case of pleomorphic adenoma arising from the soft palate and both sides of anterior tonsillar pillars in a 75-year-old man. This patient was presenting painless slow growing large swelling in the soft palate over 20 years causing mechanical obstruction of airway and food. The entire tumor mass was excised along with overlying mucosa. How to cite this article Swain SK, Sahu MC, Tripathy R. A Giant Pleomorphic Adenoma of the Palatine Arch in a 75-Year-Old Man: A Case Report with Review of Literature. Int J Head Neck Surg 2015;6(1):23-25.


2012 ◽  
Vol 2 (4) ◽  
pp. 331-334
Author(s):  
S Shrestha ◽  
CB Pun ◽  
R Basyal ◽  
T Pathak ◽  
S Bastola ◽  
...  

Polymorphous low-grade adenocarcinoma is a rare salivary gland malignant tumor of low aggressiveness, commonly occurring in minor salivary glands. Its origin in major salivary glands is considered exceedingly rare. We report a case of polymorphous low grade adenocarcinoma arising from left parotid in a 21-yearold female patient.Journal of Pathology of Nepal (2012) Vol. 2, 331-334DOI: http://dx.doi.org/10.3126/jpn.v2i4.6890


1997 ◽  
Vol 111 (7) ◽  
pp. 671-673 ◽  
Author(s):  
Camilla E. Comin ◽  
Mario Dini ◽  
Giulia Lo Russo

AbstractThe authors present a case of oncocytoma of the nasal cavity in a 60-year-old woman. The tumour shows the same histological and ultrastructural characteristics of oncocytomas arising in minor salivary glands of other sites and major salivary glands. The authors stress that the biological behaviour of oncocytomas of the nasal cavity seems related to their local growth rather than to the cytological characteristics of the tumour. The extreme rarity of this tumour in the nasal cavity is particularly emphasized. The few cases reported previously in literature are briefly reviewed.


2014 ◽  
Vol 6 (1) ◽  
pp. 10-12
Author(s):  
Thakur Rahul Tejendrasingh ◽  
Sonawale Sanjay Kumar Laxmanrao

ABSTRACT Pleomorphic adenoma is a common, benign tumor arising from the major salivary glands, most commonly from the parotid gland. In addition, they may also occur in the minor salivary glands of the hard and soft palate. Intranasal pleomorphic adenomas are unusual and may be misdiagnosed because they have greater myoepithelial cellularity and fewer myxoid stromata compared to those elsewhere. We report a case of pleomorphic adenoma of the nasal cavity arising from the nasal septum.


2016 ◽  
Vol 8 (1) ◽  
pp. 32-34
Author(s):  
HS Bhuie ◽  
Navneet Mathur ◽  
Arjun N Yogee ◽  
Raman Choudhary

ABSTRACT Myoepitheliomas are rare benign neoplasms of salivary glands representing less than 1% of all salivary gland tumors. This tumor is usually located in the parotid gland and less frequently in the submandibular gland and minor salivary glands that are distributed throughout the oral cavity. Diagnosis of tumor is based on evaluation of histological feature, although immunohistochemical analysis confirms the myoepithelial origin of tumor cells and the final diagnosis. Herein, a case of plasmacytoid myoepithelioma of soft palate in an adult male is presented along with review of the literature. How to cite this article Yogee AN, Choudhary R, Mathur N, Bhuie HS. Myoepithelioma of Soft Palate: A Case Report and Review of Literature. Int J Otorhinolaryngol Clin 2016;8(1):32-34.


2013 ◽  
Vol 5 (3) ◽  
pp. 151-153
Author(s):  
Thakur Rahul Tejendrasingh ◽  
Sonawale Sanjay Kumar Laxmanrao

ABSTRACT Pleomorphic adenoma is a common, benign tumor arising from the major salivary glands, most commonly from the parotid gland. In addition, they may also occur in the minor salivary glands of the hard and soft palate. Intranasal pleomorphic adenomas are unusual and may be misdiagnosed because they have greater myoepithelial cellularity and fewer myxoid stromata compared to those elsewhere. We report a case of pleomorphic adenoma of the nasal cavity arising from the nasal septum. How to cite this article Tejendrasingh TR, Laxmanrao SSK. Pleomorphic Adenoma of the Nasal Septum. Int J Otorhinolaryngol Clin 2013;5(3):151-153.


1995 ◽  
Vol 109 (5) ◽  
pp. 466-468 ◽  
Author(s):  
Bonnie L. Kemp ◽  
John G. Batsakis ◽  
Adel K. El-Naggar ◽  
Sophia N. Kotliar ◽  
Mario A. Luna

AbstractThe major salivary glands are considered to rarely be the sites of primary terminal duct adenocarcinomas, a neoplasm with a considerable predilection for origin from intraoral minor salivary glands. We present a clinicopathological study of 22 terminal duct adenocarcinomas of the parotid gland, the largest single series to date. A comparison between the parotid neoplasms and over 200 minor salivary gland terminal duct adenocarcinomas indicates there is little difference in biological behaviour and confirms the low-grade quality of the carcinomas, regardless of site of origin.


There are three main pairs of major salivary glands in the head and neck, namely the parotid, submandibular, and sublingual salivary glands. In addition to these major glands there are numerous minor salivary glands distributed throughout the oral cavity. These minor salivary glands are situated in the adnexal layer of the oral mucosa. This chapter covers the relevant anatomy, physiology, taking a history, clinical examination, and investigations. It then goes on to discuss xerostomia, Sjögren’s syndrome, diffuse and localized gland swelling, sialolithiasis, ranula, and disorders of the minor salivary glands.


2019 ◽  
Vol 10 ◽  
pp. 215265671988903 ◽  
Author(s):  
Madison J. Malfitano ◽  
Meghan N. Norris ◽  
Wesley H. Stepp ◽  
Griffin D. Santarelli ◽  
T. Danielle Samulski ◽  
...  

Background Hyalinizing clear cell carcinomas (HCCCs) are rare, low-grade, malignant tumors which most often arise from the minor salivary glands primarily in palate and tongue but can arise in any location with minor salivary glands including the nasopharynx. Methods A case report of primary nasopharyngeal HCCC is presented. Because of the rarity of this tumor and location, a literature search was conducted to determine the most common presenting symptoms, treatment strategies, and outcomes. Results A 48-year-old man underwent biopsy of a 4.5 cm mass of the right nasopharynx with pathology suggesting an intermediate grade mucoepidermoid carcinoma. After discussing management with the patient, an endoscopic resection was performed. Final pathology revealed an HCCC which was confirmed after negative Mastermind-like 2 (MAML2) and positive Ewing sarcoma breakpoint region 1 (ESWR1) gene rearrangements on fluorescence in situ hybridization (FISH) studies. Literature review of other nasopharyngeal HCCC cases shows diverse presentation and overall excellent prognosis through surgical and radiation therapy. Conclusion HCCCs are rare, low-grade malignant tumors of the minor salivary glands and can present as a nasopharyngeal mass. Presenting symptoms are diverse but frequently involve otologic and sinonasal disturbances. HCCC is an indolent tumor with an excellent prognostic outcome when treated appropriately with surgical resection and adjuvant radiotherapy.


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