scholarly journals Sinonasal Teratocarcinosarcoma: A Rare Clinical Entity

2012 ◽  
Vol 3 (1) ◽  
pp. 22-23
Author(s):  
Gopinath Maraignanam ◽  
L Somu

ABSTRACT Sinonasal teratocarcinosarcoma is a rare tumor of the paranasal sinuses, that shows combined features of both malignant teratoma and carcinosarcoma. It was earlier called teratoid carcinosarcoma or blastoma or teratocarcinoma or malignant teratoma. Its pecularity is its highly aggressive nature with a 5 years survival rate of 45% with treatment according to published statistics. Its treatment modality is a combination of surgery and radiotherapy. Here, we report one such case who presented with a history of one episode of torrential bleeding from left nostril and nasal obstruction for 3 months for which total excision of the tumor was done by endoscopic-assisted left lateral rhinotomy approach. Histopathology and Immunohistochemistry confirmed the diagnosis of sinonasal teratocarcinosarcoma and she was subsequently administered radiotherapy postoperatively. How to cite this article Mohanty S, Maraignanam G, Somu L. Sinonasal Teratocarcinosarcoma: A Rare Clinical Entity. Int J Head and Neck Surg 2012;3(1):22-23.

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Nuntasiri Eamudomkarn ◽  
Naratassapol Likitdee ◽  
Pilaiwan Kleebkaow ◽  
Chumnan Kietpeerakool

Massive ascites as a presentation of endometriosis is a rare clinical entity that is most commonly seen in black nulliparous females. Herein, we describe a case of a 32-year-old multiparous Thai woman who presented with a two-year history of abdominal distension. Computerized tomography of the abdominopelvic region showed an infiltrative enhancing lesion involving the cul-de-sac and perirectal region with massive loculated ascites, suggesting carcinomatosis peritonei. Abdominal paracentesis was performed to yield fluid samples for evaluation, which revealed no malignant cells, and polymerase chain reaction (PCR) was negative for tuberculosis. The patient underwent exploratory laparotomy which revealed a large amount of serosanguinous ascites, thickened matted bowel loops, and necrotic debris covering the entire surface of the peritoneum and visceral organs. The surgical procedures included drainage of 6.5 liters of ascites, lysis adhesion, biopsy of the peritoneum, and right salpingo-oophorectomy. Histologic examination revealed benign endometrial glands with stroma at the peritoneum tissue and broad ligament. Other causes of ascites were excluded. The ascites responded to drainage and hormonal suppression. A final diagnosis of endometriosis was made based on these findings. Endometriosis should therefore be considered in differential diagnosis in women of childbearing age who present with ascites.


2016 ◽  
Vol 4 (1) ◽  
pp. 443 ◽  
Author(s):  
G.S. Murali ◽  
Shubhakar Bhandary

With its inherent resistance to infection, abscess of the thyroid has been rarely encountered clinically. The disease is usually preceded by an attack of upper respiratory tract infection. The availability of potent broad spectrum antibiotics is one important factor due to which currently thyroid abscess has become a rare clinical entity. But we report a case of thyroid abscess in an otherwise 26 yr old healthy young female with a long standing goitre. She gave no history of preceding URTI. The causative organism was identified as Salmonella typhi.


2012 ◽  
Vol 5 (3) ◽  
pp. 118-122 ◽  
Author(s):  
Sumit Gupta ◽  
Sudhir Naik ◽  
Nanjundappa LNU ◽  
Rajshekar Halkud ◽  
Srihariprasad LNU ◽  
...  

ABSTRACT Background/objectives Sinonasal teratocarcinosarcoma is a rare aggressive malignant tumor arising in the sinonasal tract and a malignant neoplasm of uncertain histogenesis. As the tumor contains various components of teratoma, sarcoma and carcinoma arising from cells of embryonic origin majority of the patients suffer locoregional failure. Case report A 35-year-old patient reported with history of left-sided nasal obstruction since 2 months. A polypoid mass was seen in the left nasal cavity and a clinical diagnosis of infected antrochoanal polyp endoscopic sinus surgery was done. Histopathology with immunohistochemistry confirmation yielded the report as teratocarcinosarcoma. Intervention Medial maxillectomy with a Moure's incision was done with adjuvant intensity modulated radiotherapy and chemotherapy. Histopathological analysis of the specimen confirmed the earlier pathology. Conclusion Sinonasal teratocarcinosarcoma has a proven poor prognosis with locoregional recurrence. The disease free survival rate is nearly 28% and overall survival rate is of 46%. Optimal resection margins are to be defined and multimodality treatment in the form of postoperative radiotherapy and chemotherapy are to be standardized. How to cite this article Naik SM, Nanjundappa, Halkud R, Srihariprasad, Sidappa K, Gupta S, Rao CR. Sinonasal Teratocarcinosarcoma: A Rare Clinical Entity managed by Medial Maxillectomy and Adjuvant Chemoradiation. Clin Rhinol An Int J 2012;5(3):118-122.


2015 ◽  
Vol 4 (9) ◽  
pp. 205846011559918 ◽  
Author(s):  
Abhishek J Arora ◽  
Richa Arora

Ossification of the Achilles tendon is a rare clinical entity comprising of one or more segments of variable sized ossified masses in the fibrocartilaginous substance of the tendon. The etiology of ossification of the Achilles tendon is multifactorial with recurrent trauma and surgery comprising major predisposing factors, with others being metabolic, systemic, and infectious diseases. The possibility of a genetic predisposition towards this entity has also been raised, but has not yet been proven. We present a rare case of ossification of the bilateral Achilles tendons without any history of trauma or surgery in a 48-year-old female patient.


Author(s):  
Vijayan Sharmila ◽  
Arun Babu Thirunavukkarasu

Membranous dysmenorrhea is a rare painful clinical condition associated with spontaneous expulsion of the endometrium as an entire piece, retaining the shape of the uterus. Authors report a case of membranous dysmenorrhea in a 36 year old multiparous woman, who was not on any hormonal therapy. She presented with history of menorrhagia for 20 days and severe dysmenorrhea for one day. During her second day of hospital admission, she expelled a fleshy mass resembling a decidual cast. Histopathological examination was consistent with diagnosis of membranous dysmenorrhea. The etiology of membranous dysmenorrhea is not very clear and hence reporting such rare cases may aid in understanding the etiology and pathophysiology of this rare condition.


2013 ◽  
Vol 6 (2) ◽  
pp. 100-105
Author(s):  
Prabodh Karnik ◽  
Anuja Santosh Kulkarni ◽  
Uma Nataraj

ABSTRACT Invasive aspergillosis in an immunocompetent host is a rare clinical entity. The purpose of this article is to create awareness of existence of invasive sino-orbital aspergillosis in an immunocompetent, young, otherwise healthy host and its management with emphasizing the importance of balancing open surgical approach with endoscopic approach in order to achieve the optimum clearance of disease. A 48 years old female patient presented with 6 months history of nontender swelling over the left maxilla, 5 months history of left-sided nasal blockage and 2 months history of left orbital proptosis. How to cite this article Kulkarni AS, Karnik P, Nataraj U. Invasive Sino-orbital Aspergillosis in an Immunocompetent Host selecting a Surgical Approach: Changing Trend. Clin Rhinol An Int J 2013;6(2):100-105.


2021 ◽  
Vol 49 (2) ◽  
pp. 030006052199223
Author(s):  
Xiaolin Zhang ◽  
Hongmei Jiao ◽  
Xinmin Liu

Esophageal diverticulum with secondary bronchoesophageal fistula is a rare clinical entity that manifests as respiratory infections, coughing during eating or drinking, hemoptysis, and sometimes fatal complications. In the present study, we describe a case of bronchoesophageal fistula emanating from esophageal diverticulum in a 45-year-old man who presented with bronchiectasis. We summarize the characteristics of this rare condition based on a review of the relevant literature.


BMC Surgery ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Devendra K Jain ◽  
Gaurav Aggarwal ◽  
Parvinder S Lubana ◽  
Sonia Moses ◽  
Nitin Joshi

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