scholarly journals Caseating Granulomatous Inflammation: Think beyond Tuberculosis

2013 ◽  
Vol 3 (2) ◽  
pp. 51-54
Author(s):  
Padmavathi Devi Chaganti ◽  
YVS Prabhakar ◽  
KA Seetaram ◽  
Kalyan Babu

ABSTRACT A 33 years old male human immunodeficiency virus (HIV) positive patient on antiretroviral therapy developed caseating granulomatous inflammation of lymph nodes. He did not respond to antituberculous treatment. Subsequently, he developed gastrointestinal tract lesions. Special stains show positivity for histoplasmosis The case is presented because of its resemblance to tuberculosis. How to cite this article Chaganti PD, Prabhakar YVS, Seetaram KA, Babu K. Caseating Granulomatous Inflammation: Think beyond Tuberculosis. Int J Phonosurg Laryngol 2013;3(2):51-54.

2002 ◽  
Vol 116 (4) ◽  
pp. 288-290 ◽  
Author(s):  
C. V. Praveen ◽  
R. M. Terry ◽  
M. Elmahallawy ◽  
C. Horsfield

Pneumocystis carinii is an opportunistic infection found in patients with impaired immunity. Under favourable conditions the parasite can spread via the blood stream or lymphatic vessels and cause extrapulmonary dissemination. We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection.


2006 ◽  
Vol 14 (5) ◽  
pp. 309-311 ◽  
Author(s):  
Thekla G. Papadaki ◽  
Chrysanthi Kafkala ◽  
Ioannis P. Zacharopoulos ◽  
Jian Seyedahmadi B ◽  
Thaddeus Dryja ◽  
...  

2009 ◽  
Vol 48 (2) ◽  
pp. 157-159 ◽  
Author(s):  
Marcello Menta S. Nico ◽  
Hermes Ryoiti Higashino ◽  
Ho Yeh Li ◽  
Noemia Barbosa Carvalho ◽  
Silvia Vanessa Lourenço

Author(s):  
emre aydın ◽  
Fatma Yılmaz Aydın ◽  
Yakup Demir ◽  
Yaşar Yıldırım ◽  
Mustafa Kemal Çelen

Introduction: Human Immunodeficiency virus is a chronic infection that attacks the immune system of the human body, particularly CD4 T lymphocytes. Combined antiretroviral therapies are highly effective in virological suppression of human immunodeficiency virus infection. It has been shown that some retroviral therapies have a higher nephrotoxicity potential. As a result of renal injury, serum creatinine increases, and the estimated glomerular filtration rate is reduced. The aim of our study was to assess changes in kidney function during a 24-month period in HIV-positive patients who were begun on combined antiretroviral therapy. Material-method: A total of 127 HIV positive patients were enrolled. The patients were divided into five groups; patients who received no therapy were designated as Group 1; those that received Dolutegravir/Abacavir/Lamivudine combination as Group 2; those that received Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fumarate combination as Group 3; those that received Emtricitabine/Tenofovir Disoproxil Fumarate/Dolutegravir combination as Group 4; and those that received Emtricitabine/Tenofovir Disoproxil Fumarate/Raltegravir combination as Group 5. We compared the effects of these drugs on estimated glomerular filtration rate during a 24-month follow-up period. Results: At the 24th month of therapy, a significant difference was observed between the eGFR levels of the study groups (p:<0.001). eGFR level was significantly higher in Group 4 compared to Groups 1, 2, and 3 (p:0.009, p:<0.001, p:<0.001, respectively) while it was significantly lower in Group 5 than groups 1, 2, and 3 (p:0.005, p:<0.001, p:<0.001, respectively). No significant eGFR difference was found between Group 4 and Group 5 (p>0.05). Serum creatinine level was significantly higher in Groups 4 and 5 compared to the other groups (p<0.001). Conclusion: The use of TDF-containing regimens causes renal dysfunction. Therefore, we recommend close monitoring of renal function, especially in patients treated with TDF.


2021 ◽  
Vol 429 ◽  
pp. 118363
Author(s):  
Alessandro Di Santo ◽  
Fabio Pilato ◽  
Fioravante Capone ◽  
Liana Africa ◽  
Vincenzo Di Lazzaro

2015 ◽  
Vol 105 (5) ◽  
pp. 401-406 ◽  
Author(s):  
Endri Afesllari ◽  
Timothy J. Miller ◽  
Michael J. Huchital ◽  
Christy M. King ◽  
James S. Johnston ◽  
...  

Background Implementation of highly active antiretroviral therapy (HAART) significantly increased the life expectancy of those living with human immunodeficiency virus (HIV). Except for prevalence, scientific reports regarding clinical manifestations of plantar verrucae in the post-HAART era are lacking. The objective of this study was to compare clinical manifestations of plantar verrucae between HIV-infected and noninfected individuals and then to compare these findings with those observed before the implementation of HAART. Methods Nineteen patients with plantar verrucae (ten with HIV and nine without HIV) were examined to determine the size, number, and clinical type of verrucae present. The two groups were first compared with each other and then with previously collected data from a similar analysis conducted in 1995, before the implementation of HAART. Statistical significance was determined using the Fisher exact test or the Wilcoxon rank sum test. Results No significant differences were observed in the size, number, or clinical type of verrucae between HIV-negative and HIV-positive patients. Compared with the 1995 data, there was a significant decrease in the number of verrucae lesions per individual and a nonsignificant decrease in the average size of verrucae in HIV-positive patients. Conclusions Study results indicate that the implementation of HAART has impacted the clinical manifestations of plantar verrucae in HIV-positive individuals. Further analyses with a larger number of patients are required to confirm and substantiate these findings.


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