scholarly journals Design and Synthesis of Novel Epidermal Growth Factor Receptor Kinase Inhibitors

2005 ◽  
Vol 26 (6) ◽  
pp. 959-965 ◽  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Receptor Kinase ◽  
Design And Synthesis ◽  
Epidermal Growth

Design and Synthesis of Novel Epidermal Growth Factor Receptor Kinase Inhibitors.

ChemInform ◽  
2005 ◽  
Vol 36 (47) ◽  
Author(s):  
Jae Du Ha ◽  
Seung Kyu Kang ◽  
Kun-Do Kim ◽  
Joong-Kwon Choi ◽  
Jae Yang Kong ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Receptor Kinase ◽  
Design And Synthesis ◽  
Epidermal Growth

scholarly journals Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent

2018 ◽  
Vol 54 (54) ◽  
pp. 7479-7482 ◽  
Author(s):  
Mu Yang ◽  
Hanzhi Wu ◽  
Julie Chu ◽  
Lucas A. Gabriel ◽  
Y. Kim ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Cysteine Residue ◽  
Receptor Kinase ◽  
Epidermal Growth ◽  
Hybrid Agent ◽  
Egfr Kinase

Platinum-modified tyrosine kinase inhibitors show strong and selective EGFR kinase binding and form adducts with a pharmacologically relevant cysteine residue.

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