Locally invasive and metastatic endometrial cancer: Multiple issues functioning in a multidirectional manner

2007 ◽  
Vol 3 (5) ◽  
pp. 281
Author(s):  
Bruce Z. Kaplan, MD ◽  
Reed Phillips, MD ◽  
Dan Ratner, BA

A 32-year-old woman with locally invasive and metastatic endometrial cancer was admitted to the hospital for the treatment of crescendo pain. The effectiveness of her medical and psychosocial care was mitigated by four issues: (1) the intractable nature of her pain, (2) substance abuse, (3) mental illness, and (4) interorganizational conflict. This case report is both a chronicle and review of the literature of these multiple issues that converged together to adversely effect the patient’s overall care.

Author(s):  
Leonardo Muratori ◽  
Paola Sperone ◽  
Gabriella Gorzegno ◽  
Anna La Salvia ◽  
Giorgio Vittorio Scagliotti

Abstract Background Endometrial carcinoma is one of the most common female cancers in developed countries. Disease stage is associated with the risk of disease relapse after radical treatment. Typically, the risk of disease relapse peaks at 3 years from local radical treatment and then diminishes over time, so that late relapses (i.e., from year 5 afterward) are extremely infrequent. Here, we report two cases of women with endometrial cancer who developed a disease relapse more than 15 years after radical treatment. A review of the literature revealed other seven reports of women with relapse from endometrial cancer occurring more than 10 years after radical treatment. Case presentation Case report 1 is a 56-year-old woman with an endometrioid cancer who underwent a hysterectomy with bilateral salpingo-oophorectomy in 1998. She relapsed in the lung in 2014, 16 years from radical surgery. Case report 2, a 75-year-old woman, with an endometrioid cancer, was treated by hysterectomy with bilateral salpingo-oophorectomy and adjuvant radiotherapy. The disease relapse in the lung was detected in 2019, 22 years from radical treatment. Conclusion Although guidelines do not support oncological follow-up beyond 5 years from surgery, oncologists should consider late recurrence of endometrial carcinoma in the differential diagnosis of women presenting with metastases of uncertain origin and prior history of this disease.


2019 ◽  
Vol 15 (6) ◽  
pp. 1408
Author(s):  
Giacomo Corrado ◽  
Martina De Angeli ◽  
Mariantonia Carosi ◽  
Enrico Vizza

2018 ◽  
Vol 119 (4) ◽  
pp. 243-247
Author(s):  
Osman Nuri Dilek ◽  
Emine Özlem Gür ◽  
Turan Acar ◽  
Serpil Aydoğmuş

2008 ◽  
Vol 111 (3) ◽  
pp. 583-588 ◽  
Author(s):  
J. Albareda ◽  
M. Herrera ◽  
A. Lopez Salva ◽  
J. Garcia Donas ◽  
R. Gonzalez

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