scholarly journals Successful long-term thalidomide therapy for discoid lupus erythematosus-lichen planus overlap syndrome

2014 ◽  
Vol 20 (10) ◽  
Author(s):  
Lisa Zhang ◽  
Sonoa Au ◽  
Iris K Aronson
Keyword(s):  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Overlap Syndrome ◽  
Discoid Lupus Erythematosus

Long-term Results of Intralesional Interferon Alpha-2B in Discoid Lupus Erythematosus

1993 ◽  
Vol 20 (7) ◽  
pp. 444-446 ◽  
Author(s):  
Jesús Martínez ◽  
Ricardo F. de Misa ◽  
Pablo Boixeda ◽  
José María Arrazola ◽  
Antonio Ledo
Keyword(s):  
Interferon Alpha ◽  
Lupus Erythematosus ◽  
Long Term Results ◽  
Discoid Lupus Erythematosus ◽  
Interferon Alpha 2B

Systemic Lupus Erythematosus

2019 ◽  
Author(s):  
Kyriakos A. Kirou ◽  
Michael D. Lockshin
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Sun Exposure ◽  
Disease Classification ◽  
Discoid Lupus Erythematosus ◽  
Neurologic Disease ◽  
Systemic Lupus ◽  
Nuclear Antigens ◽  
Key Words Systemic Lupus

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune illness characterized by autoantibodies directed at nuclear antigens that cause clinical and laboratory abnormalities, such as rash, arthritis, leukopenia and thrombocytopenia, alopecia, fever, nephritis, and neurologic disease. Most or all of the symptoms of acute lupus are attributable to immunologic attack on the affected organs. Many complications of long-term disease are attributable to both the disease and its treatment. Intense sun exposure, drug reactions, and infections are circumstances that induce flare; the aim of treatment is to induce remission. This chapter is divided into sections dealing with SLE’s definitions; epidemiology; pathogenesis; disease classification, diagnosis, and differential diagnosis; and treatment. This review contains 10 figures, 12 tables, and 97 references. Key Words: Systemic lupus erythematosus, Dermatomyositis, Sjögren syndrome, rheumatoid arthritis, systemic sclerosis, Discoid lupus erythematosus, truncal psoriasiform, annular polycyclic rash

Systemic Lupus Erythematosus

2019 ◽  
Author(s):  
Kyriakos A. Kirou ◽  
Michael D. Lockshin
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Sun Exposure ◽  
Disease Classification ◽  
Discoid Lupus Erythematosus ◽  
Neurologic Disease ◽  
Systemic Lupus ◽  
Nuclear Antigens ◽  
Key Words Systemic Lupus

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune illness characterized by autoantibodies directed at nuclear antigens that cause clinical and laboratory abnormalities, such as rash, arthritis, leukopenia and thrombocytopenia, alopecia, fever, nephritis, and neurologic disease. Most or all of the symptoms of acute lupus are attributable to immunologic attack on the affected organs. Many complications of long-term disease are attributable to both the disease and its treatment. Intense sun exposure, drug reactions, and infections are circumstances that induce flare; the aim of treatment is to induce remission. This chapter is divided into sections dealing with SLE’s definitions; epidemiology; pathogenesis; disease classification, diagnosis, and differential diagnosis; and treatment. This review contains 10 figures, 12 tables, and 97 references. Key Words: Systemic lupus erythematosus, Dermatomyositis, Sjögren syndrome, rheumatoid arthritis, systemic sclerosis, Discoid lupus erythematosus, truncal psoriasiform, annular polycyclic rash

Atypical Fibroxanthoma Arising in a Scar of Discoid Lupus Erythematosus

2014 ◽  
Vol 18 (5) ◽  
pp. 353-355 ◽  
Author(s):  
Vincenzo De Francesco ◽  
Enzo Errichetti ◽  
Enrico Pegolo ◽  
Giuseppe Stinco
Keyword(s):  
Lupus Erythematosus ◽  
Fibrous Histiocytoma ◽  
Early Stage ◽  
Rare Event ◽  
Soft Tissue Sarcomas ◽  
Squamous Cell Carcinomas ◽  
Discoid Lupus Erythematosus ◽  
Atypical Fibroxanthoma ◽  
Basal Cell Carcinomas

Background: Malignant change in the scars of discoid lupus erythematosus (DLE) is a well-known event. In most cases, tumors are of epithelial origin, particularly squamous cell carcinomas and, less frequently, basal cell carcinomas and keratoacanthomas. The onset of soft tissue sarcomas in a DLE scar is a very rare event, however, because only one case of malignant fibrous histiocytoma has been described in the literature. Objective: We describe the first documented report of atypical fibroxanthoma (AFX) arising in an old scar of DLE. Results: Although we cannot exclude an accidental association between AFX and DLE, our case emphasizes that patients with DLE may develop AFX in the context of an old scar. Conclusion: Our finding further underlines the importance of strict and long-term surveillance of people with DLE to identify and remove eventual tumors at an early stage.

Evaluation of the profile of the immune cell infiltrate in lichen planus, discoid lupus erythematosus, and chronic dermatitis

Pathology ◽  
2008 ◽  
Vol 40 (7) ◽  
pp. 682-693 ◽  
Author(s):  
Mahmoud-Rezk A. Hussein ◽  
Noha M. Aboulhagag ◽  
Hesham S. Atta ◽  
Saad M. Atta
Keyword(s):  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Immune Cell ◽  
Discoid Lupus Erythematosus ◽  
Cell Infiltrate ◽  
Immune Cell Infiltrate

scholarly journals Successional occurrence of two papulosquamous disorders in HIV positive patient: a rare case report

2021 ◽  
Vol 7 (6) ◽  
pp. 869
Author(s):  
Nitika Sanjay Deshmukh ◽  
Ravindranath Brahmadeo Chavan ◽  
Anil Prakash Gosavi ◽  
Supriya Ashok Kachare
Keyword(s):  
Case Report ◽  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Rare Condition ◽  
Discoid Lupus Erythematosus ◽  
Rare Presentation ◽  
Rare Case Report ◽  
Autoimmune Conditions ◽  
Atypical Presentations ◽  
High Index Of Suspicion

<p class="abstract">Presentation of two papulosquamous disorders in a same individual is rare condition till date. Independently, psoriasis and Lichen planus (LP) are common inflammatory skin conditions affecting around 2-3% and 1% of HIV (Human immune deficiency) positive population respectively. As reviewed in the literature, psoriasis may be independently associated with other autoimmune conditions like vitiligo, alopecia areata, lichen planus, and discoid lupus erythematosus. In this article, we presented a case report of a HIV seropositive patient who suffered from psoriasis and lichen planus. The coexistence of psoriasis and lichen planus in one individual is rare and underreported in literature. Psoriasis or lichen planus may be the presenting feature of HIV infection and tends to be more severe, to have atypical presentations. Psoriasis and lichen planus can be coexistent or successionally appear one after other in one individual though rare presentation. High index of suspicion is always required while dealing with papulosquamous lesions in PLHIV.</p><p> </p>

Systemic Lupus Erythematosus

2019 ◽  
Author(s):  
Kyriakos A. Kirou ◽  
Michael D. Lockshin
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Sun Exposure ◽  
Disease Classification ◽  
Discoid Lupus Erythematosus ◽  
Neurologic Disease ◽  
Systemic Lupus ◽  
Nuclear Antigens ◽  
Key Words Systemic Lupus

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune illness characterized by autoantibodies directed at nuclear antigens that cause clinical and laboratory abnormalities, such as rash, arthritis, leukopenia and thrombocytopenia, alopecia, fever, nephritis, and neurologic disease. Most or all of the symptoms of acute lupus are attributable to immunologic attack on the affected organs. Many complications of long-term disease are attributable to both the disease and its treatment. Intense sun exposure, drug reactions, and infections are circumstances that induce flare; the aim of treatment is to induce remission. This chapter is divided into sections dealing with SLE’s definitions; epidemiology; pathogenesis; disease classification, diagnosis, and differential diagnosis; and treatment. This review contains 10 figures, 12 tables, and 97 references. Key Words: Systemic lupus erythematosus, Dermatomyositis, Sjögren syndrome, rheumatoid arthritis, systemic sclerosis, Discoid lupus erythematosus, truncal psoriasiform, annular polycyclic rash

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