scholarly journals Primary mucoepidermoid carcinoma of the breast: a with immunohistochemical analysis and comparison with salivary gland mucoepidermoid carcinomas

2013 ◽  
Vol 3 ◽  
pp. 210-215 ◽  
Author(s):  
Maria Heloisa Rached Palermo ◽  
Michelli Bárbara Pinto ◽  
Juliana Silva Zanetti ◽  
Alfredo Ribeiro-Silva
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Immunohistochemical Analysis ◽  
Carcinoma Of The Breast

scholarly journals A Rare Case of Mucoepidermoid Carcinoma ex Pleomorphic Adenoma arising in Minor Salivary Gland: Histopathological and Immunohistochemical Analysis

2015 ◽  
Vol 16 (7) ◽  
pp. 603-606
Author(s):  
Felipe Perozzo Daltoe ◽  
Liliane Janete Grando ◽  
Maria Inês Meurer ◽  
Elena Riet Correa Rivero ◽  
Filipe Modolo
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Rare Case ◽  
Periodic Acid ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumor ◽  
Immunohistochemical Analysis ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Periodic Acid Schiff

ABSTRACT Mucoepidermoid carcinoma ex pleomorphic adenoma (MCxPA) is a rare salivary gland tumor predominantly found in major salivary glands. A case of MCxPA involving the soft tissue and bone of the retromolar region of a 26-year-old man is presented. The histopathological features revealed a neoplasm with predominance of pleomorphic adenoma (PA) elements, and presence of mucoepidermoid carcinoma malignant epithelial cells in several areas. Histochemical and immunohistochemical studies were positive for periodic acid Schiff, alcian blue, cytokeratins 7, 13, 14, and 19, Bcl-2, c-erbB-2, FGF-2 and maspin in the malignant areas. The patient underwent a partial resection of the left side of the mandible with neck dissection and MCxPA diagnosis was confirmed. How to cite this article Daltoe FP, Grando LJ, Meurer MI, Rivero ERC, Modolo F. A Rare Case of Mucoepidermoid Carcinoma ex Pleomorphic Adenoma arising in Minor Salivary Gland: Histopathological and Immunohistochemical Analysis. J Contemp Dent Pract 2015;16(7):603-606.

scholarly journals Atypical Presentation of Mammary Analogue Secretory Carcinoma of the Lip

2020 ◽  
pp. 014556132095775
Author(s):  
Abdulkader Yassin-Kassab ◽  
Danielle Gainor ◽  
Ahmed Saeed Sufyan
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Atypical Presentation ◽  
Rare Tumor ◽  
Secretory Carcinoma ◽  
Carcinoma Of The Breast ◽  
Case Presentation ◽  
Mammary Analogue Secretory Carcinoma ◽  
Not Otherwise Specified ◽  
Low Incidence

Mammary analogue secretory carcinoma (MASC) of the salivary gland is a rare tumor that was first described by Skalova et al in 2010, and since then, only a few hundred cases have been reported in the literature. Prior to Skalova’s report, MASC was histologically misclassified as acinic cell carcinoma (ACC), pleomorphic adenoma, mucoepidermoid carcinoma, or adenocarcinoma, not otherwise specified. Mammary analogue secretory carcinoma has a low incidence rate overall, accounting for less than 0.3% of all salivary gland tumors. Histopathologic and cytogenic analysis of MASC is identical to secretory carcinoma of the breast, leading to the proposed name by Skalova. The purpose of this case presentation is to describe an atypical presentation of MASC, to compare this case with the classic description of MASC, and to contrast the various features of MASC to ACC in order to improve the accuracy of future diagnoses and help guide treatment.

A Case of Mucoepidermoid Carcinoma Arising from the Intraoral Minor Salivary Gland

2017 ◽  
Vol 33 (1) ◽  
pp. 39-41
Author(s):  
Hun Hee Baek ◽  
◽  
Seok Jung Hong ◽  
Mi Ji Lee ◽  
Seung Woo Kim ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Minor Salivary Gland

scholarly journals Glucose transporter protein 1 expression in mucoepidermoid carcinoma of salivary gland: correlation with grade of malignancy

2010 ◽  
Vol 91 (2) ◽  
pp. 107-113 ◽  
Author(s):  
Ana P. D. Demasi ◽  
Ana F. Costa ◽  
Albina Altemani ◽  
Cristiane Furuse ◽  
Ney S. Araújo ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Glucose Transporter ◽  
Transporter Protein ◽  
Grade Of Malignancy

Estrogen receptor expression in salivary gland mucoepidermoid carcinoma and adenoid cystic carcinoma

2004 ◽  
Vol 10 (3) ◽  
pp. 166-168 ◽  
Author(s):  
Fábio Ramôa Pires ◽  
Danyel Elias da Cruz Perez ◽  
Oslei Paes de Almeida ◽  
Luiz Paulo Kowalski
Keyword(s):  
Estrogen Receptor ◽  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Mucoepidermoid Carcinoma ◽  
Receptor Expression ◽  
Estrogen Receptor Expression ◽  
Adenoid Cystic

Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours

2012 ◽  
Vol 27 (4) ◽  
pp. 381-388 ◽  
Author(s):  
Mark R. Darling ◽  
Nelly N. Hashem ◽  
Irene Zhang ◽  
Mohamed Mohamed ◽  
Kevin Fung ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumour ◽  
Immunoperoxidase Staining ◽  
Aberrant Expression ◽  
Adenoid Cystic ◽  
Gland Tumour

Objectives Kallikrein-related peptidase 10 (KLK10) has been implicated in the development of several types of cancer. The purpose of this study was to analyze the expression of KLK10 in 3 types of salivary gland tumour and normal salivary glands. Materials and methods: A standard immunoperoxidase staining technique was used to assess the Immunoexpression profile of KLK10 in normal salivary glands and 3 types of salivary gland tumour: pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma. Results Pleomorphic adenomas showed significantly lower KLK10 levels than control tissues. Neither of the malignant tumours (adenoid cystic carcinoma and mucoepidermoid carcinoma) showed a significant alteration in the immunoreactive scores of KLK10 in comparison with the normal salivary gland tissues. KLK10 immunoreactive scores were comparable in adenoid cystic carcinoma and mucoepidermoid carcinoma. Pleomorphic adenoma had significantly lower levels of KLK10 than mucoepidermoid carcinoma. Conclusions The finding of lower KLK10 levels in pleomorphic adenoma suggests aberrant expression in a tumour that develops primarily from myoepithelial cells. A kallikrein cascade may play a role in the development and/or outcome of some salivary gland tumours.

Role of radiotherapy for mucoepidermoid carcinoma of salivary gland

Oral Oncology ◽  
1999 ◽  
Vol 35 (1) ◽  
pp. 105-111 ◽  
Author(s):  
Y Hosokawa ◽  
H Shirato ◽  
K Kagei ◽  
S Hashimoto ◽  
T Nishioka ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma

scholarly journals Prognostic Nomograms for Predicting Overall Survival and Cancer-Specific Survival of Patients with Major Salivary Gland Mucoepidermoid Carcinoma

2019 ◽  
Vol 10 (18) ◽  
pp. 4380-4388 ◽  
Author(s):  
Jia-Qian Hu ◽  
Peng-Cheng Yu ◽  
Xiao Shi ◽  
Wan-Lin Liu ◽  
Ting-Ting Zhang ◽  
...  
Keyword(s):  
Overall Survival ◽  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Major Salivary Gland ◽  
Cancer Specific Survival

scholarly journals Ki-67 Index in Salivary Gland Neoplasms

2016 ◽  
Vol 6 (1) ◽  
pp. 1-7
Author(s):  
Suma Kaza ◽  
T Jaya Mastan Rao ◽  
Anupama Mikkilineni ◽  
G Venkata Ratnam ◽  
D Ranga Rao
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Neoplasms ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Myoepithelial Carcinoma ◽  
Cell Adenoma ◽  
Ki 67 ◽  
Adenoid Cystic ◽  
Epithelial Myoepithelial Carcinoma

Abstract Assessment of proliferation is a means of predicting local recurrence and metastatic potential of malignancies. A mitotic count is not an ideal marker for proliferation in certain situations, such as salivary gland neoplasms. Ki-67 expression as a proliferation marker has been investigated in many human tumors. In the present study, Mitotic index (MI) and Ki-67 index were studied in pleomorphic adenoma, basal cell adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma epithelial myoepithelial carcinoma, carcinoma ex Pleomorphic adenoma and adenocarcinoma of salivary glands. The results were compared. The MI was similar in benign neoplasms, mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, whereas it was high in carcinoma ex pleomorphic adenoma, adenocarcinoma and adenoid cystic carcinoma. The Ki-67 index was different in basal cell adenoma and pleomorphic adenoma. It was helpful in differentiating high grade and low grade mucoepidermoid carcinoma. It highlighted the malignant behavior of epithelial myoepithelial carcinoma. It was concluded that Ki-67 in benign neoplasms is 5% or less and in malignant ones more than 23% with a few exceptions. In mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, Ki-67 index was found to be a better indicator for aggressiveness. These findings will be presented in this paper, with review of literature. How to cite this article Kaza S, Rao TJM, Mikkilineni A, Ratnam GV, Rao DR. Ki-67 Index in Salivary Gland Neoplasms. Int J Phonosurg Laryngol 2016;6(1):1-7.

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