scholarly journals Time Dependent Effect of the Combination of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation in Knee Osteoarthritis Patients

2021 ◽  
Vol 23 (04) ◽  
pp. 196-206
Author(s):  
Rekha Chaturvedi ◽  
◽  
Shabnam Joshi ◽  

Background: Osteoarthritis is a highly prevalent musculoskeletal condition. A huge variety of treatment interventions are available but have shown success to limited extent. Treatment intervention managing the symptoms both at the periphery and at the central pain processing can be a better approach to the treat this condition. Objective: The present study aimed to see the time effect of the combination of Transcranial direct current stimulation (tDCS) and Transcutaneous electrical nerve stimulation (TENS) in knee OA patients. Study design: Pre- post experimental study design. Methodology: Seventeen patients with chronic knee osteoarthritis as per American College of Rheumatology criteria were recruited in the study. The combination of tDCS and TENS was applied for 5 consecutive days over the most painful knee. The outcome measures were pain (VAS), function (six minute walk test), disability and quality of life (Knee injury and osteoarthritis outcome score) measured at the baseline, one week, two weeks and six weeks after the interventions. Data was analyzed using SPSS (version 21.0) software. Result: The result of the study showed significant improvement in pain, function and quality of life at the short term (week 1) as well as in long term (6 weeks) after the interventions. Conclusion: The combination of tDCS and TENS is a potential intervention in reducing pain and improving function both at short and long term in knee OA patients.

2014 ◽  
Vol 29 (8) ◽  
pp. 771-782 ◽  
Author(s):  
Joyce Gomes-Osman ◽  
Edelle C Field-Fote

Objective: To assess single-session effects of three different types of stimuli known to increase cortical excitability when combined with functional task practice. Design: Randomized cross-over trial. Participants: A total of 24 participants with chronic cervical spinal cord injury. Interventions: One 30-minute session of each, applied concurrently with functional task practice: transcranial direct current stimulation, vibration, and transcutaneous electrical nerve stimulation. Measurements: Nine-hole Peg Test, pinch force, visuomotor tracking, and cortical excitability were collected at pretest, posttest and late posttest (30 minutes after). Early effects (posttest minus pretest) and short-term persistence (late posttest minus pretest) were assessed using a general linear mixed model. Magnitude of effect size was assessed using the Cohen’s d. Results: Transcutaneous electrical nerve stimulation was associated with moderate, significant early effects and short-term persistence on Nine-hole Peg Test performance (1.8 ±1.8, p = 0.003, d = 0.59; 2.0 ±2.5, p < 0.001, Cohen’s d = 0.65, respectively). Transcranial direct current stimulation (1.8 ±2.5, p = 0.003, Cohen’s d = 0.52) was also associated with significant short-term persistence of moderate size on Nine-hole Peg Test performance (1.8 ±2.5, p = 0.003, Cohen’s d = 0.52) and visuomotor tracking performance ( p = 0.05, d = 0.51). Early effects on corticomotor excitability were significant for transcutaneous electrical nerve stimulation ( p = 0.003), approached significance for transcranial direct current stimulation ( p = 0.07), and only vibration was associated with significant short-term persistence ( p = 0.006). Conclusions: Meaningful improvements in aspects of hand-related function that persisted at least 30 minutes after intervention were observed with transcutaneous electrical nerve stimulation and transcranial direct current stimulation, when combined with functional task practice.


2015 ◽  
Vol 95 (1) ◽  
pp. 129-140 ◽  
Author(s):  
Brian Noehren ◽  
Dana L. Dailey ◽  
Barbara A. Rakel ◽  
Carol G.T. Vance ◽  
Miriam B. Zimmerman ◽  
...  

BackgroundFibromyalgia is a common chronic pain condition that has a significant impact on quality of life and often leads to disability. To date, there have been few well-controlled trials assessing the utility of nonpharmacological treatment modalities such as transcutaneous electrical nerve stimulation (TENS) in the management of pain and improvement in function in individuals with fibromyalgia.ObjectivesThe purpose of this study will be to complete a long-term, multicenter study to assess the effects of TENS in women with fibromyalgia.DesignThis will be a phase II randomized, double-blind, placebo-controlled, multicenter clinical trial.ParticipantsThree hundred forty-three participants with fibromyalgia will be recruited for this study.InterventionParticipants will be randomly assigned to 1 of 3 groups: the intervention (TENS), placebo, or no treatment. After completing the randomized period, all participants will receive the intervention for 1 month. The participants will be asked to use TENS at the highest tolerable level for at least 2 hours daily during physical activity.MeasurementsThe primary outcome will be pain with movement, with secondary outcomes assessing functional abilities, patient-reported outcomes, and quantitative sensory testing.LimitationsBecause having participants refrain from their typical medications is not practical, their usage and any change in medication use will be recorded.ConclusionsThe results of this study will provide some of the first evidence from a large-scale, double-blind, placebo-controlled trial on the effectiveness of TENS on pain control and quality-of-life changes in patients with fibromyalgia.


2006 ◽  
Vol 120 (6) ◽  
pp. 442-445 ◽  
Author(s):  
G Aydemir ◽  
M S Tezer ◽  
P Borman ◽  
H Bodur ◽  
A Unal

Objectives: Tinnitus can adversely affect patients' quality of life. Transcutaneous electrical nerve stimulation (TENS) may be effective in the management of tinnitus. No study has investigated the efficacy of TENS for the management of tinnitus by means of quality of life measures. In this study, we evaluated the efficacy of TENS for the management of tinnitus symptoms by using the visual analogue scale (VAS), tinnitus handicap inventory test, Nottingham health profile (NHP) and short form-36 (SF-36) questionnaires.Methods: Twenty-two patients were included in this study (male/female, 16/6; mean age, 48.04 ± 15.57 years). Nine patients had unilateral and 13 patients had bilateral tinnitus.Results: After TENS, improvement measured by VAS was only marginally significant (p = 0.059). However, after TENS, there were statistically significant improvements regarding tinnitus severity scores, tinnitus handicap inventory scores, NHP fatigue, social isolation and emotional problems scores, and many parameters measured by the SF-36 (physical functioning, general health, vitality, social functioning, role limitations due to emotional problems, and mental health)(p < 0.05).Conclusion: Transcutaneous electrical nerve stimulation is a useful method to improve the quality of life of patients with tinnitus.


2019 ◽  
Vol 47 (12) ◽  
pp. 6337-6348 ◽  
Author(s):  
Hu Cai ◽  
Qinfei Zhou ◽  
Guanai Bao ◽  
Xiangming Kong ◽  
Li-Yan Gong

Objective The aim of this study was to evaluate the therapeutic effects of transcutaneous electrical nerve stimulation (TENS) on opioid-induced constipation (OIC) and patient quality of life. Methods A total of 251 patients were randomly allocated to a treatment group, who received TENS and oral lactulose solution (n = 124), and a control group, who received only oral lactulose solution (n = 127). Constipation and quality of life after treatment were measured by comparing semiquantitative scores based on subjective symptoms. Results The defecation difficulty, incomplete defecation feeling, and overall defecation satisfaction scores of the treatment group were significantly different from those of the control group ( P = 0.018). Bowel Function Index and quality of life scores of the treatment group were significantly greater than those of the control group. The effective rates of control and treatment groups were 85.8% and 91.9%, respectively. Conclusion TENS of relevant acupuncture points significantly relieved the clinical symptoms of constipation of patients with OIC and improved their quality of life.


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