scholarly journals A comparison of sedation with midazolam–ketamine versus propofol–fentanyl during Endoscopic retrograde cholangiopancreatography in adults

2021 ◽  
Vol 23 (09) ◽  
pp. 838-852
Author(s):  
Dr.Ghassan Dakhel Ridha Alhajemi ◽  
◽  
Prof. Dr. Ayad Abbas Salman ◽  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Recovery Time ◽  
Heart Rate Recovery ◽  
The Other ◽  
Prospective Clinical Study ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy ◽  
Successful Cannulation ◽  
Number Of Patients ◽  
Adequate Sedation

Background: Patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) require adequate sedation or general anesthesia. This prospective clinical study investigated the safety and efficacy of midazolam -Ketamine versus propofol-fentanyl during ERCP procedures. patients and Methods: The study included 80 patients who underwent ERCP following anesthesiologist-administered sedation with fentanyl-propofol and other group midazolam-Ketamine. Procedural data, oxygen saturation, blood pressure, heart rate, recovery time, discharge times the effectiveness of sedation during the procedure was assess according to Modified Observer’s Assessment of Alertness/Sedation (MOAA/S) scores. Results: Sedation related complications occurred in 13 of 40 patients in group Ketamine – midazolam and 5 of 40 patients in group fentanyl-propofol included nausea / vomiting, agitation and headache. Most events were minor and did not necessitate discontinuation of the procedure. Successful cannulation was performed in all patients. the time of recovery was significantly lower in group MK with 5.15 ± 1.3 min compared to 6.15 ± 2 in group FP, and discharge was significantly. lower in group FP with 20.35 ± 0.7 min, compared to 24.15 ± 3.4 min in group MK. this occurred due to the number of patients who had side effects in midazolam-Ketamine group was more than the other group. Conclusion: We concluded that FP, more suitable for sedation and less complications rather than MK. Although no significant complications were seen.

Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography in Nonagenarians: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Umair Iqbal ◽  
Hafsa Anwar ◽  
Muhammad Ali Khan ◽  
Simcha Weissman ◽  
Shivangi T. Kothari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Meta Analysis ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

Efficacy of an Oxycodone-Propofol Combination versus a Fentanyl-Propofol Combination in Conscious Sedation during Therapeutic Endoscopic Retrograde Cholangiopancreatography in Elderly Patients

Gerontology ◽  
2020 ◽  
pp. 1-8
Author(s):  
Peipei Guo ◽  
Huisheng Wu ◽  
Lan Liu ◽  
Qiu Zhao ◽  
Zhao Jin
Keyword(s):  
Adverse Events ◽  
Elderly Patients ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Postoperative Nausea ◽  
Recovery Time ◽  
Adverse Reactions ◽  
Conscious Sedation ◽  
Endoscopic Retrograde ◽  
Patients Satisfaction ◽  
Low Incidence

<b><i>Background:</i></b> With a rapidly aging population, the need for endoscopic retrograde cholangiopancreatography (ERCP) is increasing. The commonly used sedation anesthesia in ERCP is a combination of propofol and fentanyl, even though fentanyl may cause some adverse reactions such as respiratory depression. <b><i>Objectives:</i></b> This study aimed to evaluate the efficacy of oxycodone combined with propofol versus fentanyl combined with propofol for sedation anesthesia during ERCP. <b><i>Methods:</i></b> A total of 193 patients aged from 65 to 80 years undergoing ERCP were enrolled and randomized into two groups: an “oxycodone combined with propofol” group (group OP, <i>n</i> = 97) and a “fentanyl combined with propofol” group (group FP, <i>n</i> = 96). The rate of perioperative adverse events as well as the recovery time, patients’ satisfaction, and endoscopists’ satisfaction were noted. <b><i>Results:</i></b> There was no difference in the frequency of hypotension or bradycardia between the two groups, but there were more episodes of desaturation (SpO<sub>2</sub> &#x3c;90% for &#x3e;10 s in 8.3%), postoperative nausea (7.3%), and vomiting (5.2%) in group FP than in group OP. Patients’ satisfaction in group FP was lower than that in group OP. The recovery time was longer in group FP than in group OP. <b><i>Conclusions:</i></b> Oxycodone combined with propofol was effective in ERCP, with a low incidence of perioperative adverse events.

ID: 3516964 SAFETY AND EFFICACY OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN NONAGENARIANS: IS 90 REALLY THE NEW 60? A SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Vol 93 (6) ◽  
pp. AB127
Author(s):  
Umair Iqbal ◽  
Hafsa Anwar ◽  
Muhammad Ali Khan ◽  
Simcha Weissman ◽  
Shivangi Kothari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Meta Analysis ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

scholarly journals Comparison of Recovery Time of Propofol and Midazolam with Propofol Alone for Sedation in Endoscopic Retrograde Cholangiopancreatography

2021 ◽  
Vol 15 (5) ◽  
pp. 1024-1027
Author(s):  
Asma Samreen ◽  
Aamir Waseem ◽  
Muhammad Azam ◽  
Itrat Hussain Kazmi ◽  
Aamir Bashir ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Recovery Time ◽  
Controlled Trial ◽  
P Value ◽  
Time Data ◽  
Endoscopic Retrograde ◽  
Intravenous Anesthetic ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Procedural sedation is required for multiple short duration procedures outside of the operating rooms especially in radiology and endoscopy suites. Intravenous anesthetic agent with rapid recovery profile is desirable in such circumstances. This study aims to compare two regimens of intravenous anesthetic agents. Aim: To compare the mean recovery time of propofol and midazolam with propofol alone for sedation in endoscopic retrograde cholangiopancreatography. Study Design: Randomized controlled trial. Settings: Department of Anesthesia, Shalamar Hospital, Lahore. Study Duration: June 2017 to December 2017. Methods: A total of 70 adult patients aged 20-60 years undergoing ERCP under sedation were included. Patients were given a combination of propofol and midazolam in group A while propofol alone was given in group B. After procedure, pts were transferred to recovery room and were followed for assessment of recovery time. Data were analyzed in SPSS vr 21, Independent t-test was applied & p-value ≤0.05 was considered statistically significant. Results: Significant difference was found in mean recovery time amongst both the groups. Mean recovery time in Group A (propofol and midazolam) was 19.29±4.50 minutes while in Group B (propofol alone) was 26.66±3.70 minutes showing statistically significant result with p-value = 0.0001. Conclusion: We conclude that mean recovery time with propofol plus midazolam is shorter as compared to propofol alone for sedation in ERCP. Keywords: Propofol, midazolam, sedation outside operation theatre.

Sa2067 Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatography in Pediatric Patients: A 7-Year Experience

2016 ◽  
Vol 83 (5) ◽  
pp. AB304-AB305 ◽  
Author(s):  
Parit Mekaroonkamol ◽  
Jose Nieto ◽  
Saurabh Chawla ◽  
Alvin J. Freeman ◽  
Zaid Alnoah ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Pediatric Patients ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy

scholarly journals Blind-eye cannulation as a new method for ERCP training: Can we do more than merely teach?

2020 ◽  
Vol 08 (02) ◽  
pp. E186-E188
Author(s):  
Ivo Boškoski ◽  
George Webster ◽  
Andrea Tringali ◽  
Pietro Familiari ◽  
Vincenzo Perri ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Training Session ◽  
The Other ◽  
New Method ◽  
Endoscopic Retrograde ◽  
Hands On ◽  
Technical Proficiency ◽  
Standard List

Abstract Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) requires extensive hands-on training. Currently in ERCP training there are two very important problems that need attention: lack of standardized commands for communication, and misunderstanding between the trainee and the trainer. Methods A method of “blind-eye” cannulation was developed with two paired trainees using the Boškoski-Costamagna ERCP Trainer. The trainee who was holding the duodenoscope was blind-folded and the other trainee gave instructions on what maneuvers were necessary to achieve cannulation, under the supervision of a trainer. Before starting cannulation, a standard list of commands was agreed by the operators. Results The blind-eye method of cannulation teaches the operator trainee to listen and the assistant trainee to teach. Trainees use standardized commands. During the training session the two trainees swapped roles. Conclusions Currently, we do not have proof that this type of training is useful, therefore, scientific studies are needed for confirmation. However, we believe that this ERCP model may provide an entirely safe means of improving communication and technical proficiency.

Tu1057 SAFETY AND EFFICACY OF ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IN NONAGENARIAN PATIENTS

2019 ◽  
Vol 89 (6) ◽  
pp. AB535
Author(s):  
Carlos Micames ◽  
Ana E. Colmenero ◽  
Fernando E. Melgar ◽  
Jorge Vera
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Endoscopic Retrograde ◽  
Safety And Efficacy
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