Comparison of left and right ventricular pulsed and tissue Doppler myocardial performance index values using Z-score in newborns with hypoxic-ischemic encephalopathy

Author(s):  
Hayrullah Alp ◽  
Sevim Karaaslan ◽  
Tamer Baysal ◽  
Bulent Oran ◽  
Rahmi Ors
Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Sorel Goland ◽  
Lawrence S Czer ◽  
Robert J Siegel ◽  
Kevin Burton ◽  
Tasneem Z Naqvi ◽  
...  

Objectives: Normal changes in Tissue Doppler imaging (TDI) velocities and myocardial performance index (MPI) after heart transplantation (HTx) have not been evaluated. Aim: To assess left and right ventricular (LV and RV) structure and function during the 1st year after HTx using TDI and MPI. Methods. 20 donors (mean age 35 ± 13, 20 M) had baseline echocardiogram (echo) and 20 recipients (mean age 59 ± 9, 14 M) underwent serial echo including MPI and TDI systolic (S’), early (E’) and late (A’) diastolic velocities of RV and LV during 1st year post HTx. TDI of RV and LV was not available in all donors and was taken from matched controls. Results: 96 studies (20 donors/controls and 76 recipients) were analyzed (Table ). Increase in LV mass occurred at 7 days, most likely due to post-op tissue edema or ischemic changes with normalization at 3 months. An increase in MPI and a decrease in E’, S’ velocities on TDI occurred at week 1 with gradual improvement within the 1st year (Fig ). Normalization of LV and RV MPI occurred at 6 months and LV TDI velocities at 1 year. TDI velocities of RV at 1 year remained lower than in controls. No patient had > grade IA rejection at follow-up. Myocyte size was measured in H&E-stained on biopsies at 7 days and 1 year after HTx. Although changes in myocyte size varied in individual patients, on average no significant change was found (−3% ± 6%). Conclusions: Impairment of bi-ventricular systolic and diastolic function by TDI and MPI occurs early after HTx with gradual improvement during the 1st year. This study provides for the first time the expected values of TDI velocities and MPI of both LV and RV for HTx recipients without significant rejection during the 1st year after HTx.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yasunobu Hayabuchi ◽  
Yukako Homma ◽  
Shoji Kagami

AbstractThe aims of the present study were to develop and check the utility and feasibility of a novel right ventricular (RV) functional index (RV angular velocity; RVω, s−1) derived from the angular velocity in harmonic oscillator kinematics obtained from the RV pressure waveform. We hypothesized that RVω reflects the myocardial performance index (MPI), which represents global RV function. A total of 132 consecutive patients, ranging in age from 3 months to 34 years with various cardiac diseases were included in this prospective study. RVω was defined as the difference between the peak derivative of pressure (dP/dt_max − dP/dt_min) divided by the difference between the maximum and minimum pressure (Pmax – Pmin). RVω showed significant negative correlations with the pulsed-wave Doppler-derived myocardial performance index (PWD-MPI) and the tissue Doppler imaging-derived MPI (TDI-MPI) (r = −0.52 and −0.51, respectively; both p < 0.0001). RVω also showed significant positive correlations with RV fractional area change (RVFAC) and RV ejection fraction (RVEF) (r = 0.41 and 0.39, respectively; both p < 0.0001), as well as a significant negative correlation with tricuspid E/e′ (r = −0.19, p = 0.0283). The clinical feasibility and utility of RVω for assessing global RV performance, incorporating both systolic and diastolic function, were demonstrated.


2013 ◽  
Vol 24 (3) ◽  
pp. 422-429 ◽  
Author(s):  
Bülent Koca ◽  
Funda Öztunç ◽  
Ayşe Güler Eroğlu ◽  
Selman Gökalp ◽  
Memduh Dursun ◽  
...  

AbstractBackground: Assessment of right ventricular function is a key point in the follow-up of operated patients with tetralogy of Fallot. Cardiac magnetic resonance assessment of right ventricular function is considered the gold standard. However, this technique is expensive, has limited availability, and requires significant expertise to acquire and interpret the images. Myocardial performance index and isovolumic acceleration have recently been studied for the assessment of right ventricular function and are shown to be simple yet powerful tools for assessing patients with right ventricular dysfunction of various origins. Methods: In this study, the integrity of myocardial performance index and isovolumic acceleration obtained by tissue Doppler imaging echocardiography to quantify right ventricular function was assessed in 31 patients operated for tetralogy of Fallot. Myocardial performance index and isovolumic acceleration measurements were compared with the parameters derived by cardiac magnetic resonance imaging. Results: In this study, a significant correlation has not been detected between cardiac magnetic resonance-originated right ventricular ejection fraction, pulmonary regurgitation fraction and myocardial performance index, isovolumic acceleration obtained by tissue Doppler imaging echocardiography from the lateral tricuspid annulus of the right ventricle. Conclusion: We have concluded that when evaluated separately, myocardial performance index and isovolumic acceleration obtained from tissue Doppler imaging echocardiography can be used in the long-term follow-up of patients who have been operated for tetralogy of Fallot, but that they do not show correlation with cardiac magnetic resonance-originated right ventricle ejection fraction and pulmonary regurgitation fraction.


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