scholarly journals The Endocannabinoid System as a Potential Therapeutic Target for Pain Modulation

2014 ◽  
Vol 31 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Ahmet Ulugol
Keyword(s):  
Therapeutic Target ◽  
Endocannabinoid System ◽  
Pain Modulation ◽  
Potential Therapeutic Target

scholarly journals The Endocannabinoid System: A Target for Cancer Treatment

2020 ◽  
Vol 21 (3) ◽  
pp. 747 ◽  
Author(s):  
Chiara Laezza ◽  
Cristina Pagano ◽  
Giovanna Navarra ◽  
Olga Pastorino ◽  
Maria Chiara Proto ◽  
...  
Keyword(s):  
Cell Growth ◽  
Cancer Pain ◽  
Anticancer Drugs ◽  
Therapeutic Target ◽  
Endocannabinoid System ◽  
Potential Therapeutic Target ◽  
System A ◽  
Pathological Conditions ◽  
Signaling Mechanisms

In recent years, the endocannabinoid system has received great interest as a potential therapeutic target in numerous pathological conditions. Cannabinoids have shown an anticancer potential by modulating several pathways involved in cell growth, differentiation, migration, and angiogenesis. However, the therapeutic efficacy of cannabinoids is limited to the treatment of chemotherapy-induced symptoms or cancer pain, but their use as anticancer drugs in chemotherapeutic protocols requires further investigation. In this paper, we reviewed the role of cannabinoids in the modulation of signaling mechanisms implicated in tumor progression.

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