scholarly journals The Frequency of Obstructive Sleep Apnea in Patients with Non-cystic Fibrosis Bronchiectasis

2021 ◽  
Vol 22 (4) ◽  
pp. 333-338
Author(s):  
Sermin Borekci ◽  
◽  
Yonca Sekibag ◽  
Deniz Ongel Harbiyeli ◽  
Benan Musellim ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep

Sleep, Obstructive Sleep Apnea, and Chronic Alveolar Hypoventilation in Cystic Fibrosis: Role of Noninvasive Ventilation During Sleep

2020 ◽  
Vol 9 (3) ◽  
pp. 110-117
Author(s):  
Pamela Barletta ◽  
Maria Tupayachi Ortiz ◽  
Alexandre R. Abreu ◽  
Matthias Salathe ◽  
Alejandro D. Chediak
Keyword(s):  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Noninvasive Ventilation ◽  
Obstructive Sleep ◽  
Alveolar Hypoventilation

scholarly journals 1014 Relationship Between Lung Function and Obstructive Sleep Apnea in Cystic Fibrosis

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A385-A385
Author(s):  
A Shakkottai ◽  
S Z Nasr ◽  
F Hassan ◽  
L M O’Brien ◽  
R D Chervin
Keyword(s):  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Lung Function ◽  
Forced Expiratory Volume ◽  
Apnea Hypopnea Index ◽  
Lung Function Decline ◽  
Obstructive Sleep ◽  
Larger Sample ◽  
Training Grant

Abstract Introduction The frequency of obstructive sleep apnea (OSA) may be high among patients with cystic fibrosis (CF), a life-shortening, genetic respiratory disease that affects approximately 30,000 Americans. Yet, the potential relationship between OSA and lung function has not been thoroughly explored. Methods Single-center retrospective review of polysomnography (PSG) results from 2009-2017 in referred patients with CF and available pulmonary function data (PFTs) obtained at time of PSG and at 3, 6, 9, and 12-months prior. Results Mean ages were 11.1±3.9 (sd) and 37.1±14.1 years, among 18 children and 16 adults, respectively. Mean body mass index (BMI) was normal in both groups (62.5±26.6% in children; 25.1±6.4 kg/m2 in adults). Twenty-six subjects (76%) had OSA (apnea-hypopnea index >1 in children, ≥5 in adults). Mean forced expiratory volume in 1 second percent predicted (FEV1 PPD) was higher among subjects with vs. without OSA at PSG and at each time-point in the year prior, independent of age and BMI at PSG (longitudinal mixed effects model, β=19.0, SE=8.1, p=0.028). While FEV1 PPD remained unchanged in the non-OSA group, FEV1 PPD at PSG was lower, in comparison to the year prior in subjects with OSA, with the greatest difference observed at 9-months prior to PSG (2-sample t-test, difference of -6.6% vs 0.6% in OSA vs. non-OSA groups respectively, p=0.078). Conclusion The PFTs, as daytime markers of CF lung disease severity, do not seem to reliably predict risk for OSA. In our sample, CF patients with vs. without OSA had better PFTs at baseline but they also showed a greater tendency for decline in PFTs over the year prior to OSA diagnosis. Larger sample size and longer duration of assessment may help, going forward, to assess any potential adverse impact of OSA on lung function decline. Support NIH Training Grant (T32NS007222, F32HL145915)

Evaluation of the upper airway in children and adolescents with cystic fibrosis and obstructive sleep apnea syndrome

2009 ◽  
Vol 73 (12) ◽  
pp. 1780-1785 ◽  
Author(s):  
Regina Terse Trindade Ramos ◽  
Cristina Salles ◽  
Paloma Baiardi Gregório ◽  
Alessandro Tunes Barros ◽  
Angélica Santana ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Children And Adolescents ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Upper Airway ◽  
Obstructive Sleep ◽  
Apnea Syndrome

RISK FACTORS FOR OBSTRUCTIVE SLEEP APNEA IN CYSTIC FIBROSIS

2021 ◽  
Author(s):  
Aarti Shakkottai ◽  
Sanaya Irani ◽  
Samya Z. Nasr ◽  
Louise M. O'Brien ◽  
Ronald D. Chervin
Keyword(s):  
Risk Factors ◽  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep

scholarly journals Evaluation of obstructive sleep apnea in non-cystic fibrosis bronchiectasis: A cross-sectional study

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185413 ◽  
Author(s):  
Newton Santos Faria Júnior ◽  
Jessica Julioti Urbano ◽  
Israel Reis Santos ◽  
Anderson Soares Silva ◽  
Eduardo Araújo Perez ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstructive Sleep
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