scholarly journals The Role of Pneumococcal Pneumonia among Community-Acquired Pneumonia in Adult Turkish Population: TurkCAP Study

2021 ◽  
Vol 22 (4) ◽  
pp. 339-345
Author(s):  
Esin Senol ◽  
◽  
Aykut Cilli ◽  
Hakan Gunen ◽  
Alper Sener ◽  
...  
Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Patrick M. Honore ◽  
Sebastien Redant ◽  
Thierry Preseau ◽  
Sofie Moorthamers ◽  
Keitiane Kaefer ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Saeed Shoar ◽  
Fernando H Centeno ◽  
Daniel M Musher

Abstract Background Long regarded as the second most common cause of community-acquired pneumonia (CAP), Haemophilus influenzae has recently been identified with almost equal frequency as pneumococcus in patients hospitalized for CAP. The literature lacks a detailed description of the presentation, clinical features, laboratory and radiologic findings, and outcomes in Haemophilus pneumonia. Methods During 2 prospective studies of patients hospitalized for CAP, we identified 33 patients with Haemophilus pneumonia. In order to provide context, we compared clinical findings in these patients with findings in 36 patients with pneumococcal pneumonia identified during the same period. We included and analyzed separately data from patients with viral coinfection. Patients with coinfection by other bacteria were excluded. Results Haemophilus pneumonia occurred in older adults who had underlying chronic lung disease, cardiac conditions, and alcohol use disorder, the same population at risk for pneumococcal pneumonia. However, in contrast to pneumococcal pneumonia, patients with Haemophilus pneumonia had less severe infection as shown by absence of septic shock on admission, less confusion, fewer cases of leukopenia or extreme leukocytosis, and no deaths at 30 days. Viral coinfection greatly increased the severity of Haemophilus, but not pneumococcal pneumonia. Conclusions We present the first thorough description of Haemophilus pneumonia, show that it is less severe than pneumococcal pneumonia, and document that viral coinfection greatly increases its severity. These distinctions are lost when the label CAP is liberally applied to all patients who come to the hospital from the community for pneumonia.


2012 ◽  
Vol 31 (10) ◽  
pp. 2765-2772 ◽  
Author(s):  
A. Sangil ◽  
E. Calbo ◽  
A. Robles ◽  
S. Benet ◽  
M. E. Viladot ◽  
...  

1980 ◽  
Vol 142 (2) ◽  
pp. 175-190 ◽  
Author(s):  
J. C. Guckian ◽  
G. D. Christensen ◽  
D. P. Fine

Vaccine ◽  
2011 ◽  
Vol 29 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Ruth Gil-Prieto ◽  
Laura García-García ◽  
Alejandro Álvaro-Meca ◽  
Cristina Méndez ◽  
Ana García ◽  
...  

2007 ◽  
Vol 33 (2) ◽  
pp. 197
Author(s):  
David L. Schriger ◽  
Jerome R. Hoffman ◽  
Richelle J. Cooper ◽  
Malkeet Gupta

Pneumologia ◽  
2019 ◽  
Vol 68 (1) ◽  
pp. 8-14
Author(s):  
Gina Amanda ◽  
Dianiati Kusumo Sutoyo ◽  
Erlina Burhan

Abstract Streptococcus pneumoniae is the most common aetiology of community-acquired pneumonia (CAP). It has many virulence factors, the most important being a polysaccharide capsule (Cps). There are 97 different serotypes of pneumococcal based on Cps which include both colonization and invasive serotypes. Pneumococcal pneumonia may exist as a result of either aspiration of bacteria in the nasopharynx or inhalation of droplet nuclei which contains bacteria until they reach the lower respiratory tract. This condition will activate both innate and adaptive immune system. The diagnosis of pneumococcal pneumonia is established in a patient who has the signs and symptoms of pneumonia, accompanied by the detection of S. pneumoniae in microbiology examination. Pneumococcus may also penetrate into a normally sterile site such as bloodstream, meninges, and pleural cavity, and infection of pneumococcus in those sites are defined as an invasive pneumococcal disease (IPD). High bacterial load, dysfunction of the immune system, and co-colonization of another microorganism may also lead to IPD.


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