scholarly journals ANALYSIS OF THE CORRELATIONS OF THE HEART RATE VARIABILITY AND TURBULENCE PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION II DEGREE

2016 ◽  
pp. 58-64
Author(s):  
T. V. Aleynikova

Objective: to analyze the correlations of the parameters of heart rate variability (HRV) and heart rate turbulence (HRT) in patients with arterial hypertension of the II-nd degree. Material and methods. We have studied the parameters of heart rate variability and turbulence in 214 persons with arterial hypertension of the II-nd degree, of them 80.8 % having ventricular arrhythmias according to the Holter monitoring. We have analyzed the correlations of the parameters with the patient’s age, average heart rate (HR), circadian index (CI), left ventricular mass index (LVMI) and left ventricular ejection fraction (LVEF). The statistical analysis of the results has been made using the analytical package «Statistica» 10.0. Results. We have revealed statistically significant correlations of the HRV parameters with the age of patients, average HR, circadian index, ejection fraction. Thus, high level of the statistical significance of the interrelation of HRV parameters has been confirmed. We have received statistically significant correlations of the HRT parameters with the left ventricular mass index (LVMI), ejection fraction, HR average, quantity ventricular extrasystoles. High level of the statistical significance of the interrelation of HRT parameters (TO and TS) has been revealed. Conclusion. The received results can be used during the selection of the group of patients with arterial hypertension having high risk for unfavorable outcomes. Taking into account the features of the heart rate variability and turbulence parameters and factors associated with them this will enable the individualization of the assessment of the risk in arterial hypertension as much as possible and prescription of adequate treatment for each patient.

2020 ◽  
Vol 73 (5) ◽  
pp. 943-946
Author(s):  
Olha M. Chernatska ◽  
Liudmyla N. Prystupa ◽  
Hanna A. Fadieieva ◽  
Alina V. Liashenko ◽  
Yuliia O. Smiianova

The aim is the analysis of hyperuricemia influence on the heart features in patients with arterial hypertension. Materials and methods: We include 75 patients with arterial hypertension which were divided in two groups according to the level of uric acid in the blood, 30 practically healthy people. Patients from the I group (n = 40) had arterial hypertension and coexistent hyperuricemia; ІІ (n = 35) – arterial hypertension. Left ventricular mass index was determined for left ventricular hypertrophy confirmation. We used clinical, anthropometric, biochemical, instrumental, statistical method. Serum uric acid level was observed by the reaction with uricase. Left ventricular mass index was calculated as left ventricular mass to body surface area ratio. The results were analyzed statistically by SPSS 21 and Graphpad. Results: Left ventricular mass index was significantly higher (р = 0,0498) in patients from the І group (109,7 ± 3,21) g/m2 comparable with the ІІ (97,6 ± 5,35) g/m2 and increased in proportion to the biggest level of uric acid (r = 0,31; p = 0,04) in patients with arterial hypertension and hyperuricemia. Conclusions: Concentric and excentric left ventricular hypertrophy, increased left ventricular mass index proportionally to uric acid levels (r = 0,31; p = 0,04) is the confirmation of important role of hyperuricemia in the left ventricular hypertrophy development in patients with arterial hypertension.


1998 ◽  
Vol 85 (6) ◽  
pp. 2270-2276 ◽  
Author(s):  
Bernard Geny ◽  
Anne Charloux ◽  
Eliane Lampert ◽  
Jean Lonsdorfer ◽  
Pascal Haberey ◽  
...  

We investigated the atrial (ANP) and brain natriuretic peptides (BNP), catecholamines, heart rate, and blood pressure responses to graded upright maximal cycling exercise of eight matched healthy subjects and cardiac-denervated heart transplant recipients (HTR). Baseline heart rate and diastolic blood pressure, together with ANP (15.2 ± 3.7 vs. 4.4 ± 0.8 pmol/l; P < 0.01) and BNP (14.3 ± 2.6 vs. 7.4 ± 0.6 pmol/l; P< 0.01), were elevated in HTR, but catecholamine levels were similar in both groups. Peak exercise O2uptake and heart rate were lower in HTR. Exercise-induced maximal ANP increase was similar in both groups (167 ± 34 vs. 216 ± 47%). Enhanced BNP increase was significant only in HTR (37 ± 8 vs. 16 ± 8%; P < 0.05). Similar norepinephrine but lower peak epinephrine levels were observed in HTR. ANP and heart rate changes from rest to 75% peak exercise were negatively correlated ( r = −0.76, P < 0.05), and BNP increase was correlated with left ventricular mass index ( r = 0.83, P < 0.01) after heart transplantation. Although ANP increase was not exaggerated, these data support the idea that the chronotropic limitation secondary to sinus node denervation might stimulate ANP release during early exercise in HTR. Furthermore, the BNP response to maximal exercise, which is related to the left ventricular mass index of HTR, is enhanced after heart transplantation.


1970 ◽  
Vol 6 (1) ◽  
pp. 18-28
Author(s):  
MP Gautam ◽  
U Ghimire Gautam ◽  
S Dwivedi ◽  
S Rijal

Background: Alcohol drinking is cardio-protective; however its beneficial and harmful effects depend on the amount consumed. This work is designed to assess the impact of prolonged non-moderate drinking in left ventricular mass index and left ventricular ejection fraction and the correlation of their severity with total lifetime intake amount. Materials and methods: Fifty non-moderate drinkers (>25 g/day) for last 10 years and 50 non-drinker-volunteers were selected. Detail echocardiographic assessment was done and findings were compared and severity was correlated with lifetime amount. Results: Mean daily intake, duration and lifetime intake amount of alcohol were 64.1 g, 21.9 years and 501.9 Kg respectively. The mean ejection fraction and left ventricular mass index were 47.2% and 105.3 g/m2. There was significant difference when compared with controls. Eighty-two percent drinking subjects had abnormal echo, most common were regurgitations (52%), diastolic dysfunction (46%), raised ventricular mass (44%), systolic dysfunction (40%), and dilated left atrium and ventricle (38%). Thirty-four percent of subjects had echo features consistent with dilated cardiomyopathy. Palpitation and dyspnea in combination were the only symptoms associated with severity of echo changes. There was strong negative correlation of lifetime intake amount with ejection fraction (r = -0.91, p<0.001); however its relationship with ventricular mass index was not statistically significant (r = 0.23, p>0.05). Conclusions: Prolonged non-moderate drinking causes significant echocardiographic abnormalities mainly systolic dysfunction and increased left ventricular mass index. The total lifetime and daily amount of alcohol are well correlated with systolic dysfunction; however their relationships with the left ventricular mass index were non-conclusive. Key words: Alcohol; left ventricular mass; cardiomyopathy DOI: 10.3126/jcmsn.v6i1.3598 Journal of College of Medical Sciences-Nepal, 2010, Vol. 6, No. 1, 18-28


2006 ◽  
Vol 151 (4) ◽  
pp. 829-836 ◽  
Author(s):  
Peter Alter ◽  
Wolfram Grimm ◽  
Anna Vollrath ◽  
Friederike Czerny ◽  
Bernhard Maisch

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