Ratio of Excess ED ILI Visits to Seroprevalence, Influenza A/H1N1 Infection, FL, 2009

During the 2009 influenza pandemic, due to the 2009 pandemic influenza A (pH1N1) virus, there were an estimated 44 infections for every excess emergency department visit for influenza-like illness in Florida.

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Pandemic influenza A(H1N1) 2009 breakthrough infections and estimates of vaccine effectiveness in Germany 2009-2010

Eurosurveillance ◽

10.2807/ese.15.18.19561-en ◽

2010 ◽

Vol 15 (18) ◽

Author(s):

O Wichmann ◽

P Stöcker ◽

G Poggensee ◽

D Altmann ◽

D Walter ◽

...

Keyword(s):

Pandemic Influenza ◽

Influenza A ◽

Influenza Pandemic ◽

Rapid Assessment ◽

Screening Method ◽

Age Groups ◽

Vaccine Effectiveness ◽

Influenza A H1n1 ◽

Reported Data ◽

2009 Influenza Pandemic

During the 2009 influenza pandemic, a monovalent AS03-adjuvanted vaccine was almost exclusively used in Germany for immunisation against the 2009 pandemic influenza A(H1N1) virus. One-dose vaccination was recommended for all age groups. We applied the screening method for the rapid assessment of vaccine effectiveness (VE) based on reported data of vaccinated and unvaccinated pandemic influenza cases and vaccination coverage estimates. Preliminary results demonstrate excellent VE in persons aged 14-59 years (96.8%; 95% confidence interval (CI): 95.2-97.9) and moderately high VE in those 60 years or older (83.3%; 95% CI: 71.0-90.5).

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European Pandemic Influenza Preparedness Planning: A Review of National Plans, July 2016

Disaster Medicine and Public Health Preparedness ◽

10.1017/dmp.2018.60 ◽

2018 ◽

Vol 13 (03) ◽

pp. 582-592 ◽

Cited By ~ 11

Author(s):

Maaike Droogers ◽

Massimo Ciotti ◽

Peter Kreidl ◽

Angeliki Melidou ◽

Pasi Penttinen ◽

...

Keyword(s):

Pandemic Influenza ◽

Influenza A ◽

Influenza Pandemic ◽

Small Population ◽

Pandemic Preparedness ◽

Preparedness Planning ◽

Influenza A H1n1 ◽

Robust Planning ◽

2009 Influenza Pandemic ◽

The Impact

AbstractPandemic influenza A (H1N1) commenced in April 2009. Robust planning and preparedness are needed to minimize the impact of a pandemic. This study aims to review if key elements of pandemic preparedness are included in national plans of European countries. Key elements were identified before and during the evaluations of the 2009 pandemic and are defined in this study by 42 items. These items are used to score a total of 28 publicly available national pandemic influenza plans. We found that plans published before the 2009 influenza pandemic score lower than plans published after the pandemic. Plans from countries with a small population size score significantly lower compared to national plans from countries with a big population (P <.05). We stress that the review of written plans does not reflect the actual preparedness level, as the level of preparedness entails much more than the existence of a plan. However, we do identify areas of improvement for the written plans, such as including aspects on the recovery and transition phase and several opportunities to improve coordination and communication, including a description of the handover of leadership from health to wider sector management and communication activities during the pre-pandemic phase. (Disaster Med Public Health Preparedness. 2019;13:582-592)

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Pandemic influenza A(H1N1) 2009 virus outbreak among boarding school pupils in Madagascar: compliance and adverse effects of prophylactic oseltamivir treatment

The Journal of Infection in Developing Countries ◽

10.3855/jidc.1318 ◽

2011 ◽

Vol 5 (03) ◽

pp. 156-162 ◽

Cited By ~ 9

Author(s):

Soatiana Rajatonirina ◽

Jean-MicheI Heraud ◽

Laurence Randrianasolo ◽

Norosoa Razanajatovo ◽

Tombo Ramandimbisoa ◽

...

Keyword(s):

Adverse Effects ◽

Pandemic Influenza ◽

Influenza A ◽

Prophylactic Treatment ◽

Boarding School ◽

H1n1 Infection ◽

Influenza Like Illness ◽

Initial Investigation ◽

Influenza A H1n1

Introduction: In October 2009, the first outbreak of pandemic influenza A(H1N1) 2009 virus in Madagascar occurred at a school in Antananarivo. Among the first 12 cases, five were reported in boarding pupils at the school. The school closed 10 days into the outbreak. Mass oseltamivir prophylactic treatment was used to contain the outbreak. This study aimed to determine the transmission of infection among boarding school pupils and to evaluate the adverse effects of oseltamivir chemoprophylactic treatment and their impact on compliance. Methodology: After conducting an initial investigation of the outbreak we administered a questionnaire to 132 boarders who were present after the school re-opened. Questions addressed symptoms of influenza-like illness, compliance with chemoprophylaxis, and adverse effects. Results: Of 59 boarders, 20 (45.0%) had confirmed pandemic influenza A (H1N1) infection. Among the asymptomatic boarders, compliance with oseltamivir chemoprophylaxis was moderate: 56.2% took the full 10-day course, and 66.9% completed at least seven days. In contrast, among symptomatic boarders, only two did not take the full course of oseltamivir. Fifty percent of the boarders receiving oseltamivir experienced symptoms such as fatigue (38.7%), difficulty concentrating (22.6%) and headaches (19.4%). Bad compliance was not associated with adverse effects. Conclusion: Since the symptoms of pandemic influenza A(H1N1) 2009 virus were generally mild, the burden of adverse effects must be considered when deciding on mass oseltamivir chemoprophylaxis among teenagers.

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Faculty Opinions recommendation of Paediatric mortality related to pandemic influenza A H1N1 infection in England: an observational population-based study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7219957.7468055 ◽

2010 ◽

Author(s):

Simon Nadel ◽

Ajanta Kamal

Keyword(s):

Pandemic Influenza ◽

Influenza A ◽

Population Based ◽

H1n1 Infection ◽

Population Based Study ◽

Influenza A H1n1

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Influenza-Like Illness in a Community Surrounding a School-Based Outbreak of 2009 Pandemic Influenza A (H1N1) Virus-Chicago, Illinois, 2009

Clinical Infectious Diseases ◽

10.1093/cid/ciq025 ◽

2010 ◽

Vol 52 (Supplement 1) ◽

pp. S94-S101 ◽

Cited By ~ 7

Author(s):

K. B. Janusz ◽

J. E. Cortes ◽

F. Serdarevic ◽

R. C. Jones ◽

J. D. Jones ◽

...

Keyword(s):

Pandemic Influenza ◽

Influenza A ◽

H1n1 Virus ◽

Influenza Like Illness ◽

School Based ◽

Influenza A H1n1

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Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ‎possible cohort effect following the 2009 influenza pandemic

Eurosurveillance ◽

10.2807/1560-7917.es.2019.24.15.1900104 ◽

2019 ◽

Vol 24 (15) ◽

Cited By ~ 6

Author(s):

Danuta M Skowronski ◽

Siobhan Leir ◽

Gaston De Serres ◽

Michelle Murti ◽

James A Dickinson ◽

...

Keyword(s):

General Population ◽

Influenza A ◽

Influenza Pandemic ◽

Age Distribution ◽

Cohort Effect ◽

Surveillance Network ◽

Medical Visits ◽

Influenza A H1n1 ◽

2009 Influenza Pandemic ◽

Negative Controls

Introduction Findings from the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) suggest children were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic. Aim To compare the age distribution of A(H1N1)pdm09 cases in 2018/19 to prior seasonal influenza epidemics in Canada. Methods The age distribution of unvaccinated influenza A(H1N1)pdm09 cases and test-negative controls were compared across A(H1N1)pdm09-dominant epidemics in 2018/19, 2015/16 and 2013/14 and with the general population of SPSN provinces. Similar comparisons were undertaken for influenza A(H3N2)-dominant epidemics. Results In 2018/19, more influenza A(H1N1)pdm09 cases were under 10 years old than controls (29% vs 16%; p < 0.001). In particular, children aged 5–9 years comprised 14% of cases, greater than their contribution to controls (4%) or the general population (5%) and at least twice their contribution in 2015/16 (7%; p < 0.001) or 2013/14 (5%; p < 0.001). Conversely, children aged 10–19 years (11% of the population) were under-represented among A(H1N1)pdm09 cases versus controls in 2018/19 (7% vs 12%; p < 0.001), 2015/16 (7% vs 13%; p < 0.001) and 2013/14 (9% vs 12%; p = 0.12). Conclusion Children under 10 years old contributed more to outpatient A(H1N1)pdm09 medical visits in 2018/19 than prior seasonal epidemics in Canada. In 2018/19, all children under 10 years old were born after the 2009 A(H1N1)pdm09 pandemic and therefore lacked pandemic-induced immunity. In addition, more than half those born after 2009 now attend school (i.e. 5–9-year-olds), a socio-behavioural context that may enhance transmission and did not apply during prior A(H1N1)pdm09 epidemics.

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