scholarly journals Serosurveillance of Anti SARS-Cov-2 Antibodies among Essential Workers in Navi Mumbai - A Single Centre Study

2021 ◽  
Vol 11 (7) ◽  
pp. 99-104
Author(s):  
Ujwala Maheshwari ◽  
Jyotsna Sahai ◽  
Vivek Hebbar
Keyword(s):  
Service Providers ◽  
Tertiary Care ◽  
Herd Immunity ◽  
Care Hospital ◽  
Frontline Workers ◽  
Police Personnel ◽  
Antibody Titres ◽  
Precautionary Measures ◽  
A Prospective Study ◽  
Essential Service

Background – COVID – 19 is the latest raging pandemic that the world is facing at the moment. Frontline workers have been highly exposed to this disease and majority of them have suffered from this deadly disease too. Studying the prevalence of antibodies among frontline workers in different areas is crucial for understanding the potential risk of transmission, the prevalence of herd immunity, vaccine deployment and risk stratification in different areas of work. Materials and Methods – A prospective study was conducted in a tertiary care hospital of Navi Mumbai on 200 essential service providers, 100 HCWs and 100 police personnel, of which 2 police personnel dropped out of the study. This study was conducted over a period of 2 days, i.e, 20th and 21st May 2021 and it included answering a questionnaire and drawing blood to detect SARS COV-2 antibodies. Results – Out of the total 198 participants, there were 130 males and 68 females. Most of the participants were in the 30 – 39 years age group and 41% participants had suffered from COVID – 19 in the past one year. 60.10% participants had developed IgG antibodies against COVID – 19. The highest titre of antibodies found was between 1 – 10 amongst both groups followed by antibody levels more than 100 among HCWs. Subsequently, it was found that there was a 72% seropositivity rate amongst frontline workers whereas only a 48% positivity rate in HCWs. Conclusion – Measuring antibody titres allows determination of prevalence of COVID – 19 infection amongst heavily exposed individuals, who have been badly affected by the 2 waves of this pandemic. This serosurvey also helped us confirm that there is a declining trend of antibodies during convalescence phase and that even though the infectivity rate is high amongst essential service providers, not all developed a sustained antibody response. These findings uphold the need for strict precautionary measures and that laxity must not be observed while following the same to contain the pandemic. Key words: Antibodies, COVID -19, SARS-COV-2, Serosurveillance, Health Care Workers, Police Personnel, Frontline Workers.

Enhancing the empiric antibiotic selection by introducing an antibiogram toolkit in a tertiary care hospital in Southern India – A prospective study

2021 ◽  
Author(s):  
Sadagoban G. Krishnamoorthy ◽  
Vyshak Raj ◽  
Balasubramaniam Viswanathan ◽  
Ganga Priyadharshini Dhanasekaran ◽  
Dhivyaprasath Palaniappan ◽  
...  
Keyword(s):  
Prospective Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Southern India ◽  
Care Hospital ◽  
Antibiotic Selection ◽  
Empiric Antibiotic ◽  
A Prospective Study

scholarly journals Efficacy of Probiotic Saccharomyces boulardii as an Adjuvant Therapy in Acute Childhood Diarrhoea

2017 ◽  
Vol 36 (3) ◽  
pp. 250-255 ◽  
Author(s):  
Dillip Kumar Dash ◽  
Mrutunjaya Dash ◽  
M.D. Mohanty ◽  
Naresh Acharya
Keyword(s):  
Hospital Stay ◽  
Tertiary Care ◽  
Acute Diarrhoea ◽  
Oral Rehydration Therapy ◽  
Saccharomyces Boulardii ◽  
Care Hospital ◽  
Oral Rehydration ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

Introduction: Administration of S. boulardii in addition to rehydration therapy in diarrhea found to be beneficial in many aspects owing to a variety of causes and importantly it is was not associated with any adverse effects.Material and Methods: We conducted a prospective study of children suffering from acute diarrhoea, at a private tertiary care hospital. Children were divided into 2 groups randomly as per odd(Group 1 ) and even (Group 2) bed allotted in indoor at the time of admission: Group 1 included children on oral rehydration therapy (ORT) + Zinc + Saccharomyces boulardii (Probiotic 5 billion CFU twice daily) and Group 2 comprised of children on ORT+ Zinc. Our objective was to systematically review data on the effect of S. boulardii on acute childhood diarrhoea.Results: Out of a total of 126 children less than 2 years, 2-6 years and 6-14 years were 72 (57.14%), 42(33.33%) and 12(09.52%) respectively. The duration of diarrhoea in Group 1 was 26.31 hours and Group 2 was 47.81 hours (p<0.01). The frequency of diarrhoea showed improvement within 24 and 72 hours in Group 1 and Group 2 respectively (p<0.01).Similarly, the mean duration of hospital stay was 2.68 days in Group 1 and 4.8 days in Group 2.The treatment cost was INR 850 and INR 1650 while social cost was INR 1250 and 2600 in Group 1 and 2 respectively.Conclusion:This study shows that S. boulardii reduced the duration, frequency and hospital stay of diarrhoea thereby reducing the treatment and social costs.J Nepal Paediatr Soc 2016;36(3):250-255

scholarly journals ANALYSIS OF ADVERSE DRUG REACTIONS SPONTANEOUSLY REPORTED TO ADVERSE DRUG MONITORING CENTRE OF A TERTIARY CARE HOSPITAL–PROSPECTIVE STUDY

2018 ◽  
Vol 10 (1) ◽  
pp. 23
Author(s):  
Gajanan P. Kulkarni ◽  
Lokesh V. Patil
Keyword(s):  
Prospective Study ◽  
Adverse Drug Reactions ◽  
Causality Assessment ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Monitoring Centre ◽  
Organ Systems ◽  
A Prospective Study

Objective: To assess ADRs with reference to causative drugs, organ systems involved and seriousness of reactions.Methods: A prospective study conducted over a period of 1 y. The spontaneous adverse drug reactions reported between July 2016 and July 2017 at AMC centre BRIMS, Bidar were analyzed using Naranjo’s scale. Causality assessment of suspected drugs involved, system affected, and seriousness of reactions was assessed.Results: GIT system was most commonly involved, followed by generalized features, skin and appendages, CNS i. e, extrapyramidal system and dizziness, hearing and vestibular systems.Conclusion: Majority of the ADRs reported were mild to moderate severity and 20% can be categorized as severe reactions, which needed to treat under hospitalization

scholarly journals Halitosis: Its Aetiology and Psychosocial Impact- A Hospital Based Study

2021 ◽  
Vol 29 (2) ◽  
pp. 145-150
Author(s):  
Gopika Kalsotra ◽  
Monica Manhas ◽  
Sachin Gupta ◽  
Heemani Bhardwaj ◽  
Parmod Kalsotra ◽  
...  
Keyword(s):  
Social Life ◽  
Laryngopharyngeal Reflux ◽  
Systemic Disease ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Psychosocial Impact ◽  
Care Hospital ◽  
Female Ratio ◽  
Study Results ◽  
A Prospective Study

Introduction Halitosis means bad or unpleasant odour from oral cavity. It causes embarrassment to the patients and affects their social life and communication. This study aims to find the causes of halitosis and to assess its psychosocial impact. Materials and Methods A prospective study was conducted in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care hospital. It included 165 patients, presenting to the ENT OPD with chief complains of oral malodour for at least 3 months. The patients in the age above 15 years and below 75 years, irrespective of gender, were included in the study. Results The age of the patients ranged from 15 to 75 years with a mean age of 52.24 ± 15.67 with male: female ratio of 7:10. The most common cause of halitosis in the present study included chronic rhinosinusitis (38.7%), gingivitis/periodontitis (19.39%), tonsillitis (4.84%), laryngopharyngeal reflux (2%), deep neck space infections (1.2%). In 23.56%, the halitosis was a symptom of an underlying malignancy. Conclusion Halitosis from an extra oral origin can be the sign of an underlying systemic disease or malignancy. The consultation should be done with the periodontist, ENT specialist and a physician.

Sign in / Sign up

Export Citation Format

Share Document