scholarly journals EFFECTS OF PROBIOTIC SACCHAROMYCES BOULARDII AND CO-TRIMOXAZOLE ON SOME HAEMATOLOGICAL PARAMETERS IN ADULT WISTAR RATS

2021 ◽  
Vol 2 (2) ◽  
pp. 55-62
Author(s):  
P. A. Obazelu ◽  
I. A. Aruomaren ◽  
C. C. Nwangwu
Keyword(s):  
Body Weight ◽  
Blood Cell ◽  
Cell Count ◽  
Cell Volume ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Packed Cell Volume ◽  
Saccharomyces Boulardii ◽  
Total White Blood Cell ◽  
Blood Cell Count

Saccharomyces boulardii is a probiotic yeast used as a nutritional supplement. Co-trimoxazole, is a broad-spectrum antimicrobial agent used in the prophylaxis and treatment of infections.The goal of this study was to evaluate the individual and interactive effects of probiotic Saccharomyces boulardii and co-trimoxazole on some haematological parameters in albino rats. Thirty (30) albino Wistar rats weighing 150-200g were divided into five groups; Basal, A, B, C, and D, with six animals in each group. Group A (control) was given a normal rat pellet (standardized feed) and clean water (pH 6.5- 8.5). Group B was administered 5.5mg/kg body weight of the commercial probiotics (Saccharomyces boulardii). Group C was administered 4.4mg/kg body weight of co-trimoxazole. Group D was administered 5.5mg/kg body weight of the commercial probiotics and 4.4mg/kg body weight of co-trimoxazole. All administrations were done using a gavage tube for 15 days. Blood samples were collected for analysis on days 0, 5 and 15. The results showed that Saccharomyces boulardii caused a significant increase (P<0.05) in total white blood cell count and packed cell volume of the treated groups at day 5. On day 15, the total white blood cell count (10.67±0.66), packed cell volume (43.23±0.47), platelet count (932±38.89) and mean platelet volume (8.53±0.38) showed a significant increase (P<0.05) in the probiotic group. The co-trimoxazole group showed a significant reduction (P<0.05) in the packed cell volume and total white blood cell count. This study shows that Saccharomyces boulardii has a positive effect on the haematological profile of the test animals.

Assessment of White Blood Cell Count, Packed Cell Volume, Phagocytic Functions, Serum Albumin and Plasma Iron in HIV Infected Patients

2010 ◽  
Vol 135 ◽  
pp. S110 ◽  
Author(s):  
Charles Onyenekwe ◽  
Prince Ele ◽  
Nkiruka Ukibe ◽  
Michael Ezeani ◽  
Clement Ezechukwu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Serum Albumin ◽  
Cell Count ◽  
Cell Volume ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Packed Cell Volume ◽  
Blood Cell Count ◽  
Plasma Iron

scholarly journals Serum Levels of anti-BCG, Albumin and Packed Cell Volume and White Blood Cell Count in Subjects with HIV and Malaria Co-morbidity

2008 ◽  
Vol 36 (1) ◽  
pp. 17-22
Author(s):  
Chinedum Charles Onyenekwe ◽  
Nkiruka Ukibe ◽  
Samuel Chukwuemeka Meludu ◽  
Michael Ezeani ◽  
Ngozi Ofiaeli ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Cell Volume ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Packed Cell Volume ◽  
Serum Levels ◽  
Blood Cell Count ◽  
Co Morbidity

scholarly journals Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
David R. Mack ◽  
Bradley Saul ◽  
Brendan Boyle ◽  
Anne Griffiths ◽  
Cary Sauer ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Total White Blood Cell ◽  
Blood Cell Count ◽  
New Onset

scholarly journals Total white blood cell count, liver enzymes, and metabolic syndrome in schizophrenia

2016 ◽  
Vol 46 ◽  
pp. 259-264 ◽  
Author(s):  
Görkem KARAKAŞ UĞURLU ◽  
Semra ULUSOY KAYMAK ◽  
Mustafa UĞURLU ◽  
Sibel ÖRSEL ◽  
Ali ÇAYKÖYLÜ
Keyword(s):  
Metabolic Syndrome ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Liver Enzymes ◽  
Total White Blood Cell ◽  
Blood Cell Count

EFFECT OF AGING AQUEOUS NITROGEN MUSTARD ON WHITE BLOOD CELL COUNT, BODY WEIGHT, AND WALKER 256 TUMOR IN THE RAT

1963 ◽  
Vol 41 (2) ◽  
pp. 417-425 ◽  
Author(s):  
W. R. Inch ◽  
J. A. McCredie
Keyword(s):  
Body Weight ◽  
Blood Cell ◽  
Tumor Growth ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Nitrogen Mustard ◽  
Blood Cell Count ◽  
Walker 256 ◽  
Walker 256 Tumor

Aging an aqueous solution of nitrogen mustard up to 3 days did not alter significantly its ability to decrease the white blood cell count, body weight, or the growth of the established Walker 256 tumor in the rat. There was a direct relationship between the decrease in white blood cell count and depression of tumor growth but not between the depression of body weight and tumor growth. The acidity of aqueous nitrogen mustard (0.5 mg/ml) increased exponentially with time up to 100 days but was not related to the ability to decrease the white blood cell count, body weight, or tumor growth.

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