Left Atrial Rupture Secondary to Myxomatous Mitral Valve Disease in 11 Dogs

2014 ◽  
Vol 50 (6) ◽  
pp. 405-408 ◽  
Author(s):  
Reid K. Nakamura ◽  
Emily Tompkins ◽  
Nicholas J. Russell ◽  
Sarah A. Zimmerman ◽  
Danielle L. Yuhas ◽  
...  

The purpose of this retrospective study was to evaluate the long-term outcome in dogs with left atrial rupture secondary to myxomatous mitral valve disease. Eleven client-owned dogs met the inclusion criteria for the study. Median age was 11.6 yr (range, 8.3–17.8 yr), and median weight was 5.8 kg (range, 3.8–15.2 kg). Of the 11 dogs, 10 survived the initial 24 hr after diagnosis and 5 of the dogs were still alive at the conclusion of data collection. The median survival of all dogs was 203 days. Dogs with no previous history of congestive heart failure (CHF) at the time of diagnosis had a significantly longer median survival time (345 days) compared with dogs with a previous history of CHF (160 days, P = 0.0038). Outcome of dogs with myxomatous mitral valve disease presenting with left atria rupture was more favorable than previously reported, and dogs without previous CHF survived the longest.

Author(s):  
Hironobu Nishiori ◽  
Hiroyuki Watanabe ◽  
Yuichi Hirano ◽  
Masayoshi Otsu

We report a case of a 63-year-old man without a history of atrial fibrillation or mitral valve disease who was admitted to our hospital. Echocardiography revealed a large left atrial mass attached to the atrial septum. We suspected the mass to be a myxoma, but it turned out to be a large thrombus after the surgery. Left atrial thrombus without mitral valve disease or atrial fibrillation is rare. Although the degree of urgency varies based on the case, early surgical resection is recommended for a large left atrial thrombus to prevent embolism.


2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Qinghong Li ◽  
Allison Heaney ◽  
Natalie Langenfeld-McCoy ◽  
Brittany Vester Boler ◽  
Dorothy P. Laflamme

Abstract Background Myxomatous mitral valve disease (MMVD), the most common naturally-occurring heart disease in dogs, is associated with alterations in energy metabolism, oxidative stress and inflammation. Energy deprivation plays a causal role in the development of heart failure. This study was designed to determine if a cardiac protection blend (CPB) of nutrients containing medium-chain triglycerides as an alternative energy source, fish oil to reduce inflammation, antioxidants, and other key nutrients important to cardiac health and function could slow or prevent MMVD progression. Nineteen dogs with early stage MMVD and 17 breed-, age-, and sex-matched healthy dogs were enrolled for a 6-month blinded, placebo-controlled study. Dogs in each cardiac health group were randomly assigned to either control diet (CON) or CPB-supplemented diet. Echocardiography was performed at baseline, 3 months and 6 months. Results No changes were found in healthy dogs. While MMVD-CON dogs had an average 10% increase over baseline in left atrial diameter (LAD) and left atrial to aortic root ratio (LA/Ao) at 6 months, MMVD-CPB dogs showed 3% decreases, resulting significant diet by time interactions (P = 0.037, P = 0.005, respectively). More MMVD-CON dogs progressed from stage B1 to B2 during the study. A positive correlation was found between 6-month changes in LAD and blood pressures in MMVD-CPB dogs (systolic: P = 0.050, diastolic: P = 0.035) but not MMVD-CON dogs. Conclusions Our results demonstrated efficacy of CPB-based dietary intervention in reducing LA size and mitral regurgitation, and in slowing or preventing the progression of early MMVD in dogs.


2019 ◽  
Vol 36 (8) ◽  
pp. 1559-1565 ◽  
Author(s):  
Matteo Cameli ◽  
Carlotta Sciaccaluga ◽  
Giulia E. Mandoli ◽  
Flavio D’Ascenzi ◽  
Charilaos Tsioulpas ◽  
...  

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