Presample Volume Necessary to Obtain Accurate Laboratory Parameters from Central Venous Catheters in Dogs

2022 ◽  
Vol 58 (1) ◽  
pp. 1-6
Author(s):  
Yekaterina Buriko ◽  
Megan Murray ◽  
Rebecka Hess ◽  
Deborah Silverstein

ABSTRACT We compared laboratory parameters from central venous catheters using multiple presample volumes (PSVs) to venipuncture values. Blood was obtained from dogs for a venous blood gas, packed red blood cell volume (PCV), total solids (TS), and a coagulation panel. Blood was drawn both by venipuncture and from the catheter (using PSVs 300%, 600%, and 1200% of the dead space volume). Twenty dogs were enrolled. Venipuncture values were significantly higher than those obtained from the catheter for PCV (300% [P = .007], 600% [P = .005], and 1200% [P = .02]), TS (300% [P = .006] and 600% [P = .04]), and lactate (600% [P = .04] and 1200% [P = .01]). Venipuncture values were significantly lower than those obtained from a catheter for pH (1200% [P = .008]) and chloride (300% [P = .04], 600% [P = .003], and 1200% [P = .03]). An increase was found in prothrombin time in samples drawn with 600% PSV compared with 1200% (P = .008). The PCV and TS are diluted when smaller PSVs are used. A 1200% PSV best approximated the PCV and TS obtained by venipuncture. A 300% PSV may be adequate to evaluate coagulation and venous blood gas values.

2009 ◽  
Vol 25 (2) ◽  
pp. 104-110 ◽  
Author(s):  
Allan J. Walkey ◽  
Harrison W. Farber ◽  
Charles O'Donnell ◽  
Howard Cabral ◽  
Janet S. Eagan ◽  
...  

2015 ◽  
Vol 77 (7) ◽  
pp. 865-869 ◽  
Author(s):  
Jun TAMURA ◽  
Takaharu ITAMI ◽  
Tomohito ISHIZUKA ◽  
Sho FUKUI ◽  
Kenjirou MIYOSHI ◽  
...  

Nephron ◽  
2018 ◽  
Vol 139 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Sarah J. Schrauben ◽  
Dan Negoianu ◽  
Cristiana Costa ◽  
Raphael M. Cohen ◽  
Stanley Goldfarb ◽  
...  

Author(s):  
Marwa Salah Ghanem ◽  
Heba Wagih Abdelwahab ◽  
Nesrine Saad Farrag ◽  
Ahmed M. Hamad

Objectives: Arterial blood samples are the gold standard test but these are more difficult to get than venous samples. In this study we assessed the possibility of utilization of venous (peripheral and central) blood gas samples in evaluation of subjects with respiratory failure instead of arterial samples. Methods: critically ill subjects with respiratory failure had paired venous (peripheral and central) and arterial samples taken. Assessment of agreement between blood gas samples (arterial and venous) as regard PH, Pco2 and HCO3 was done using Bland–Altman analyses. The spearmen correlation and linear regression tests were also performed to assess the degree of association between arterial and venous samples. Results: 100subjects were included. A good agreement was found between venous (peripheral and central) and arterial values of pHand HCO3.The agreements between peripheral venous and arterial PH and HCO3 values is higher than agreements between arterial and central venous measures. Conclusions: venous blood gas analysis (mainly peripheral samples) could replace arterial blood gas analysis in the evaluation of acid base balance in subjects with respiratory failure


2018 ◽  
Vol 35 (5) ◽  
pp. 511-518
Author(s):  
Scott E. Rudkin ◽  
Craig L. Anderson ◽  
Tristan R. Grogan ◽  
David A. Elashoff ◽  
Richard M. Treger

Background and Objectives: In severe circulatory failure agreement between arterial and mixed venous or central venous values is poor; venous values are more reflective of tissue acid–base imbalance. No prior study has examined the relationship between peripheral venous blood gas (VBG) values and arterial blood gas (ABG) values in hemodynamic compromise. The objective of this study was to examine the correlation between hemodynamic parameters, specifically systolic blood pressure (SBP) and the arterial–peripheral venous (A-PV) difference for all commonly used acid–base parameters (pH, Pco 2, and bicarbonate). Design, Setting, Participants, and Measurements: Data were obtained prospectively from adult patients with trauma. When an ABG was obtained for clinical purposes, a VBG was drawn as soon as possible. Patients were excluded if the ABG and VBG were drawn >10 minutes apart. Results: The correlations between A-PV pH, A-PV Pco 2, and A-PV bicarbonate and SBP were not statistically significant ( P = .55, .17, and .09, respectively). Although patients with hypotension had a lower mean arterial and peripheral venous pH and bicarbonate compared to hemodynamically stable patients, mean A-PV differences for pH and Pco 2 were not statistically different ( P = .24 and .16, respectively) between hypotensive and normotensive groups. Conclusions: In hypovolemic shock, the peripheral VBG does not demonstrate a higher CO2 concentration and lower pH compared to arterial blood. Therefore, the peripheral VBG is not a surrogate for the tissue acid–base status in hypovolemic shock, likely due to peripheral vasoconstriction and central shunting of blood to essential organs. This contrasts with the selective venous respiratory acidosis previously demonstrated in central venous and mixed venous measurements in circulatory failure, which is more reflective of acid–base imbalance at the tissue level than arterial blood. Further work needs to be done to better define the relationship between ABG and both central and peripheral VBG values in various types of shock.


2010 ◽  
Vol 27 (10) ◽  
pp. 890-896 ◽  
Author(s):  
Oliver M Theusinger ◽  
Caroline Thyes ◽  
Philippe Frascarolo ◽  
Sebastian Schramm ◽  
Burkhardt Seifert ◽  
...  

2017 ◽  
Vol 17 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Sima Rahim-Taleghani ◽  
Alireza Fatemi ◽  
Mostafa Alavi Moghaddam ◽  
Majid Shojaee ◽  
Abdelrahman Ibrahim Abushouk ◽  
...  

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