UPAYA MENGURANGI CHANGE OVER TIME PADA PROSES PENJAHITAN DI SEWING LINE A20 PT. DF

Tina Martina; Nur Rofiqoh Utami; Pratiwi Wulansari

doi:10.53298/texere.v17i2.84

UPAYA MENGURANGI CHANGE OVER TIME PADA PROSES PENJAHITAN DI SEWING LINE A20 PT. DF

Texere ◽

10.53298/texere.v17i2.84 ◽

2021 ◽

Vol 17 (2) ◽

Author(s):

Tina Martina ◽

Nur Rofiqoh Utami ◽

Pratiwi Wulansari

Keyword(s):

Lean Manufacturing ◽

Change Over Time ◽

Set Up ◽

Over Time

Pada industri pakaian jadi pelayanan dan kepuasan buyer menjadi hal penting dalam menghadapi persaingan agar dapat terus tumbuh dan berkembang. Order produksi setiap tahun terdiri dari berbagai macam style yang akan berganti setelah selesai diproduksi. Perusahaan akan melakukan penetapan waktu yang harus dicapai dalam menyelesaikan satu order, sehingga dapat berpengaruh pada efisiensi waktu proses dikarenakan seringnya aktivitas change over. Change over merupakan pergantian aktivitas produksi disuatu lini produksi dari satu produk ke produk lainnya. Metoda yang akan digunakan untuk mengurangi change over time (COT) pada lini produksi yaitu menggunakan Quick Change Over (QCO). Tujuan mengurangi COT untuk mengefisiensikan waktu proses produksi walaupun tidak untuk menambah kapasitas produksi. Waktu yang dibutuhkan selama set up mesin dalam QCO menjadi faktor yang paling lama sehingga beberapa proses set up harus disederhanakan sesuai dengan prinsip lean manufacturing. Upaya mengurangi COT pada proses penjahitan yaitu dengan penerapan pemeliharaan mesin yang terjadwal, menempatkan operator sesuai dengan skill matrix dan mempersiapkan aksesoris ketika diperlukan bagian produksi. Hasil setelah penerapan metoda QCO untuk style yang repeat order menunjukan bahwa COT line A20 mengalami penurunan, walaupun belum memenuhi standar target yang ditetapkan oleh perusahaan. Penurunan COT ini akan berdampak pada peningkatan produktivitas dan efisiensi di line A20.

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Acute effects of drugs on C.elegans movement reveal complex responses and plasticity

10.1101/299719 ◽

2018 ◽

Author(s):

Mark Spensley ◽

Samantha Del Borrello ◽

Djina Pajkic ◽

Andrew G Fraser

Keyword(s):

Stress Response ◽

Drug Treatment ◽

Biological Networks ◽

Metabolic Inhibitor ◽

Acute Effects ◽

Normal Behaviour ◽

Change Over Time ◽

Acute Responses ◽

Set Up ◽

Over Time

AbstractMany drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of drugs on C.elegans movement and examined the effects of a range of compounds including neuroactive drugs, toxins, environmental stresses and novel compounds on worm movement over a time period of 3 hours. We find that many treatments show complex acute responses — a phase of rapid paralysis is followed by one or more recovery phases. The recoveries are not the result of some generic stress response but are specific to the drug e.g. recovery from paralysis due to a neuroactive drug requires neurotransmitter pathways whereas recovery from a metabolic inhibitor requires metabolic changes. Finally, we also find that acute responses can vary greatly across development and that there is extensive and complex natural variation in acute responses. In summary, acute responses are sensitive probes of the ability of biological networks to respond to drug treatment and these responses can reveal the action of unexplored pathways.Author SummaryDrugs are powerful tools that let us switch on or off key pathways in whole animals and watch the effects. Here we set up a simple assay to measure how drugs affect the movement of the simple nematode C.elegans — crucially, we look how those responses change over time. We find that worms have complex responses to many different drugs — they go through clear phases of paralysis and recovery. The recovery from the initial effect of any drug is not due to a generic stress response but is specific to the way each drug acts. We find for example that worms can recover from paralysis driven by one neurotransmitter pathway by activating a different neurotransmitter pathway or from paralysis caused by loss of one metabolic pathway by turning on a second one. These complex responses show how the basic genetic networks that are needed for normal behaviour and function can rewire and respond to the effect of many drugs. Importantly, the responses can vary in many ways — different aged worms or different individuals can have different responses and capturing how drug responses change over time is critical to dissect this complexity.

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Co-operative cross-platform courseware development

Research in Learning Technology ◽

10.3402/rlt.v4i1.9948 ◽

2011 ◽

Vol 4 (1) ◽

Cited By ~ 1

Author(s):

R. D. Harding ◽

S. W. Lay ◽

H. Moule

Keyword(s):

Academic Community ◽

Single Subject ◽

Change Over Time ◽

Cross Platform ◽

Software Platforms ◽

Set Up ◽

Different Parts ◽

Over Time

Of all the TLTP projects, the UKMCC (UK Mathematics Courseware Consortium) has involved the largest number of institutions in authoring courseware. This was part of a deliberate attempt to set up an 'open courseware' system which can continue to be adapted and grow even after the end of TLTP funding. In turn, such an objective requires a cross-platform approach to courseware development. Even when considering the academic community across a single subject at just one time, there will be a variety of hardware and software that people will want to use, but a ghost of a case can be made out for attempting some sort of standardization. When change over time is considered, it is inconceivable that hardware and software platforms will remain unchanging, and one way to manage changing standards is to have a courseware structure that permits variety. This allows different parts of a collection of materials to evolve at different speeds.DOI:10.1080/0968776960040105

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