scholarly journals CT-Guided Transthoracic Biopsy of Lung Lesions Using a Non-Coaxial Biopsy Needle Technique: CT Characteristics Predictive for Diagnostic Accuracy and Pneumothorax

2021 ◽  
Vol 105 (1) ◽  
Author(s):  
Barbara Geeroms ◽  
Lesley Cockmartin ◽  
Johan Coolen ◽  
Adriana Dubbeldam ◽  
Johny Verschakelen ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Ct Guided ◽  
Biopsy Needle ◽  
Lung Lesions ◽  
Needle Technique ◽  
Transthoracic Biopsy

scholarly journals Initial Experience in CT-Guided Percutaneous Transthoracic Needle Biopsy of Lung Lesions Performed by a Pulmonologist

2019 ◽  
Vol 8 (6) ◽  
pp. 821 ◽  
Author(s):  
June Hong Ahn ◽  
Jong Geol Jang
Keyword(s):  
Diagnostic Accuracy ◽  
Complication Rate ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Safe Procedure ◽  
Transthoracic Needle Biopsy ◽  
Ct Guided ◽  
Lung Lesions ◽  
Percutaneous Transthoracic Needle Biopsy

In the diagnosis of lung lesions, computed tomography (CT)-guided percutaneous transthoracic needle biopsy (PTNB) has a high diagnostic yield and a low complication rate. The procedure is usually performed by interventional radiologists, but the diagnostic yield and safety of CT-guided PTNB when performed by pulmonologists have not been evaluated. A retrospective study of 239 patients who underwent CT-guided PTNB at Yeungnam University Hospital between March 2017 and April 2018 was conducted. A pulmonologist performed the procedure using a co-axial technique with a 20-gauge needle. Then diagnostic yield and safety were assessed. The overall sensitivity, specificity, positive predictive value, and negative predictive value for the diagnosis of malignancy were 96.1% (171/178), 100% (46/46), 100% (171/171), and 86.8% (46/53), respectively. The diagnostic accuracy was 96.9% (217/224) and the overall complication rate was 33.1% (82/248). Pneumothorax, hemoptysis, and hemothorax occurred in 27.0% (67/248), 5.2% (13/248), and 0.8% (2/248) of the patients, respectively. Univariate analyses revealed that pneumothorax requiring chest tube insertion was a significant risk factor (odds ratio, 25.0; p < 0.001) for diagnostic failure. CT-guided PTNB is a safe procedure with a high diagnostic accuracy, even when performed by an inexperienced pulmonologist. The results were similar to those achieved by interventional radiologists as reported in previously published studies.

scholarly journals P36 Diagnostic Accuracy and Complication Rate of CT-Guided Core Biopsies of Lung Lesions in a Thoracic Oncology Unit in Mexico

2018 ◽  
Vol 13 (9) ◽  
pp. S175
Author(s):  
S. Campos Gomez ◽  
M.A. Morales-Ruíz ◽  
J.J. Valdés-Andrade ◽  
J. Esquivel-Gutiérrez ◽  
D.E. Aguirre-Quezada ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Complication Rate ◽  
Ct Guided ◽  
Lung Lesions ◽  
Oncology Unit

scholarly journals Cone-Beam CT-Guided Lung Biopsies: Results in 94 Patients

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1068
Author(s):  
Daniel Gulias-Soidan ◽  
Nilfa Milena Crus-Sanchez ◽  
Daniel Fraga-Manteiga ◽  
Juan Ignacio Cao-González ◽  
Vanesa Balboa-Barreiro ◽  
...  
Keyword(s):  
Cone Beam Ct ◽  
Cone Beam ◽  
Fluoroscopy Time ◽  
Ct Guided ◽  
Lung Lesions ◽  
Transthoracic Biopsy ◽  
Diagnostic Capacity ◽  
Malignant Lesions ◽  
Lung Biopsies ◽  
Technical Failures

Background: The aim of this study was to evaluate the diagnostic capacity of Cone-Beam computed tomography (CT)-guided transthoracic percutaneous biopsies on lung lesions in our setting and to detect risk factors for possible complications. Methods: Retrospective study of 98 biopsies in 94 patients, performed between May 2017 and January 2020. To obtain them, a 17G coaxial puncture system and a Siemens Artis Zee Floor vc21 archwire were used. Descriptive data of the patients, their position at the time of puncture, location and size of the lesions, number of cylinders extracted, and complications were recorded. Additionally, the fluoroscopy time used in each case, the doses/area and the estimated total doses received by the patients were recorded. Results: Technical success was 96.8%. A total of 87 (92.5%) malignant lesions and 3 (3.1%) benign lesions were diagnosed. The sensitivity was 91.5% and the specificity was 100%. We registered three technical failures and three false negatives initially. Complications included 38 (38.8%) pneumothorax and 2 (2%) hemoptysis cases. Fluoroscopy time used in each case was 4.99 min and the product of the dose area is 11,722.4 microGy/m2. Conclusion: The transthoracic biopsy performed with Cone-Beam CT is accurate and safe in expert hands for the diagnosis of lung lesions. Complications are rare and the radiation dose used was not excessive.

A novel technique for CT-guided transthoracic biopsy of lung lesions: improved biopsy accuracy and safety

2015 ◽  
Vol 25 (11) ◽  
pp. 3354-3360 ◽  
Author(s):  
Daniel Yaffe ◽  
Matthew Koslow ◽  
Hassan Haskiya ◽  
David Shitrit
Keyword(s):  
Ct Guided ◽  
Lung Lesions ◽  
Novel Technique ◽  
Transthoracic Biopsy

Diagnostic accuracy and complication rate of CT-guided fine needle aspiration biopsy of lung lesions: A study based on the experience of the cytopathologist

2010 ◽  
Vol 51 (5) ◽  
pp. 527-533 ◽  
Author(s):  
Adriano Massimiliano Priola ◽  
Sandro Massimo Priola ◽  
Aldo Cataldi ◽  
Marisa Di Franco ◽  
Francesco Pazè ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Fine Needle Aspiration ◽  
Complication Rate ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Ct Guided ◽  
Lung Lesions ◽  
Fine Needle ◽  
Group A ◽  
Group B

Background: CT-guided transthoracic needle biopsy is a well-established technique for the diagnosis of focal lung lesions. Fine needle aspiration biopsy (FNAB) requires the presence of a cytopathologist on-site to assess the adequacy of samples. For this reason FNAB is less and less used, and core biopsy is the first-line procedure when an experienced cytopathologist is not immediately available. Purpose: To evaluate the accuracy and complication rate of CT-guided FNAB of lung lesions according to the experience of the cytopathologist on-site. Material and Methods: A total of 321 consecutive biopsies were considered. Immediate cytological assessment was performed by an experienced cytopathologist for the first 165 procedures (group A) and by two training pathologists for the remaining 156 biopsies (group B). At the time of FNAB the pathologist assigned a semiquantitative score (0–3) to each specimen to assess its diagnostic quality. All variables between the two groups were analyzed by chi-square and Student's t test. A P value <0.05 was considered statistically significant. Results: For all procedures, overall diagnostic accuracy was 80% for cytology alone, with no statistical difference between the two groups for diagnostic accuracy and sample score assigned. In all, 75% of the cytological samples (75% group A, 74% group B) obtained a higher score with a specific diagnosis of histotype. A post biopsy pneumothorax was detected in 27% of biopsies (25% group A, 28% group B). Thirteen patients (4.0%) required chest tube insertion for treatment. For all cases, the pneumothorax rate was significantly affected by the number of samples obtained ( P=0.02), but not by the pleural punctures ( P=0.15). There was no statistically significant difference between the two groups concerning the number of needle passes and complication rate ( P>0.05). Conclusion: The efficacy and safety of CT-guided FNAB is not significantly affected by the training level of the cytopathologist on-site. Moreover, the number of specimens obtained for each procedure is a risk factor for pneumothorax.

scholarly journals P1-085: Factors affecting diagnostic accuracy of ct-guided transthoracic needle biopsy of lung lesions: results of 660 consecutive procedures

2007 ◽  
Vol 2 (8) ◽  
pp. S583-S584
Author(s):  
Adriano M. Priola ◽  
Sandro M. Priola ◽  
Silvia Novello ◽  
Aldo Cataldi ◽  
Luca Errico ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Transthoracic Needle Biopsy ◽  
Ct Guided ◽  
Lung Lesions ◽  
Factors Affecting

scholarly journals Coaxial technique-promoted diagnostic accuracy of CT-guided percutaneous cutting needle biopsy for small and deep lung lesions

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192920 ◽  
Author(s):  
Lu Zhang ◽  
Lei Shi ◽  
Zhiping Xiao ◽  
Hong Qiu ◽  
Ping Peng ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Ct Guided ◽  
Lung Lesions ◽  
Cutting Needle

Accuracy of CT-guided transthoracic needle biopsy of lung lesions: Results of 612 consecutive procedures

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 18022-18022
Author(s):  
U. Ricardi ◽  
A. M. Priola ◽  
S. M. Priola ◽  
S. Novello ◽  
A. Cataldi ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Inflammatory Cells ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Lesion Size ◽  
Maximum Diameter ◽  
Transthoracic Needle Biopsy ◽  
Ct Guided ◽  
Lung Lesions

18022 Background: CT-guided transthoracic needle biopsy (TNB) is commonly used in diagnostic work-up of lung lesions. The availability of a on-site pathologist at the time of the procedure ameliorate its sensitivity, reduce the number of biopsies and false negatives. Methods: 612 procedures (608 patients with a CT-documented central or peripheral pulmonary lesion) performed at S. Luigi Hospital between November 2002 and August 2005 were prospectively analyzed; 66% males, median age was 66 years (range 29–87). Ineligibility criteria for the procedure included severe coagulopathy, previous contralateral pneumonectomy, lesions with a maximum diameter less than 5 mm or the impossibility to understand the procedure or to maintain the clinostatism for the time of the procedure. The on-site pathologist assigned to each specimen a semiquantitative score: 0 for bloody sample without other cells, 1 for aspecific benign or inflammatory cells, 2 for malignant cells without histotype characterization and 3 for well established benign or malignant histotype. Results: Most of the procedures was performed by fine needle aspiration biopsy, while in a minority of cases a tru-cut biopsy was requested. In 57.2% of the cases a single transthoracic access (range 1–4) was used and in 31% the procedure was repeated on the basis of the radiologist/pathologist judgment. In 154 patients a surgical resection was subsequently performed, while 454 were patients non-surgical. A score of 3 was obtained in 71% of cases (88% malignancies), 2 in 12.5%, 1 in 7.5% and 0 in 9%. A definitive diagnosis was made in 83.5% of procedures, while a score of 0–1 was assigned in 101 cases. Among 458 malignancies there were 411 lung cancer, 7 non-epithelial cancers and 40 metastases with only 1 false positive. The diagnostic accuracy for benign and malignant lesions was 67% and 92%, respectively (Pearson’s test p<0.005) with overall diagnostic accuracy of 83.3%. The variables affecting diagnostic accuracy were final diagnosis (benign 67%, malignant 92%, p<0.001) and lesion size (lesion 5 cm 78%, p<0.05). The presence of cavitation or necrotic areas and location of the lesion didn’t affect the diagnostic accuracy. Conclusion: In consecutive cases of CT-guided TNB final diagnosis and lesion size affect diagnostic accuracy. No significant financial relationships to disclose.

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