Role of Doppler Ultrasound in Comparison With MDCT Angiography in the Assessment of Lower Limb PAD

2021 ◽  
Vol 15 (11) ◽  
pp. 2936-2937
Author(s):  
Mehwish Tahir ◽  
Sadaf Iqbal ◽  
Maimoona Gulshan
Keyword(s):  
Doppler Ultrasound ◽  
Lower Limb ◽  
Multidetector Ct ◽  
Duplex Ultrasound ◽  
Arterial Disease ◽  
Radiology Department ◽  
Atherosclerotic Plaques ◽  
Mdct Angiography ◽  
Peripheral Arterial

Aim: Role of Doppler ultrasound in comparison with MDCT angiography in the assessment of lower limb Peripheral arterial disease. Methodology: This study was conducted in Radiology department of Shalamar Hospital Lahore. A total of 42 patients (31 males and 11 females) diagnosed with PAD by using both Doppler ultrasound and MDCTA were included. The data collected was entered, tabulated and statistically analyzed on IBM-SPSS 25.0 version. Results: A total of 336 arterial segments were assessed on both modalities. Duplex ultrasound detected 278 (83%) positive patent segments, 124(37%) segments showing atherosclerosis and 63(19%) segments with stenosis/thrombus, in comparison to MDCTA which was able to detect 221 (66%) patent vessels,153(46%) segments showing atherosclerosis and 114 (34%) segments showing thrombus/ stenosis. The results showed that the MDCTA was able to detect 15% more arterial segments with stenosis/ thrombus and 9% more segments with atherosclerotic plaques as compared to Doppler. Conclusion: Doppler ultrasound is the modality of choice in detecting grade 0 and 1 PAD while. MDCTA is more accurate in assessing patients with grade 2 and 3 PAD who need surgical intervention. Key Words: PAD, Duplex ultrasound, Multidetector CT Angiography

scholarly journals The Role of Circulating Biomarkers in Peripheral Arterial Disease

2021 ◽  
Vol 22 (7) ◽  
pp. 3601
Author(s):  
Goren Saenz-Pipaon ◽  
Esther Martinez-Aguilar ◽  
Josune Orbe ◽  
Arantxa González Miqueo ◽  
Leopoldo Fernandez-Alonso ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Lower Limb ◽  
Prediction Models ◽  
Arterial Disease ◽  
Cardiac Damage ◽  
Thrombotic Occlusion ◽  
Medical Treatments ◽  
Peripheral Arterial ◽  
Inflammatory Molecules

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is one of the most prevalent CV conditions worldwide in subjects >65 years, estimated to increase greatly with the aging of the population, becoming a severe socioeconomic problem in the future. The narrowing and thrombotic occlusion of the lower limb arteries impairs the walking function as the disease progresses, increasing the risk of CV events (myocardial infarction and stroke), amputation and death. Despite its poor prognosis, PAD patients are scarcely identified until the disease is advanced, highlighting the need for reliable biomarkers for PAD patient stratification, that might also contribute to define more personalized medical treatments. In this review, we will discuss the usefulness of inflammatory molecules, matrix metalloproteinases (MMPs), and cardiac damage markers, as well as novel components of the liquid biopsy, extracellular vesicles (EVs), and non-coding RNAs for lower limb PAD identification, stratification, and outcome assessment. We will also explore the potential of machine learning methods to build prediction models to refine PAD assessment. In this line, the usefulness of multimarker approaches to evaluate this complex multifactorial disease will be also discussed.

scholarly journals Lower-limb hot-water immersion acutely induces beneficial hemodynamic and cardiovascular responses in peripheral arterial disease and healthy, elderly controls

2017 ◽  
Vol 312 (3) ◽  
pp. R281-R291 ◽  
Author(s):  
Kate N. Thomas ◽  
André M. van Rij ◽  
Samuel J. E. Lucas ◽  
James D. Cotter
Keyword(s):  
Blood Pressure ◽  
Lower Limb ◽  
Water Immersion ◽  
Duplex Ultrasound ◽  
Arterial Disease ◽  
Hot Water ◽  
Healthy Elderly ◽  
Limb Perfusion ◽  
Peripheral Arterial ◽  
Hot Water Immersion

Passive heat induces beneficial perfusion profiles, provides substantive cardiovascular strain, and reduces blood pressure, thereby holding potential for healthy and cardiovascular disease populations. The aim of this study was to assess acute responses to passive heat via lower-limb, hot-water immersion in patients with peripheral arterial disease (PAD) and healthy, elderly controls. Eleven patients with PAD (age 71 ± 6 yr, 7 male, 4 female) and 10 controls (age 72 ± 7 yr, 8 male, 2 female) underwent hot-water immersion (30-min waist-level immersion in 42.1 ± 0.6°C water). Before, during, and following immersion, brachial and popliteal artery diameter, blood flow, and shear stress were assessed using duplex ultrasound. Lower-limb perfusion was measured also using venous occlusion plethysmography and near-infrared spectroscopy. During immersion, shear rate increased ( P < 0.0001) comparably between groups in the popliteal artery (controls: +183 ± 26%; PAD: +258 ± 54%) and brachial artery (controls: +117 ± 24%; PAD: +107 ± 32%). Lower-limb blood flow increased significantly in both groups, as measured from duplex ultrasound (>200%), plethysmography (>100%), and spectroscopy, while central and peripheral pulse-wave velocity decreased in both groups. Mean arterial blood pressure was reduced by 22 ± 9 mmHg (main effect P < 0.0001, interaction P = 0.60) during immersion, and remained 7 ± 7 mmHg lower 3 h afterward. In PAD, popliteal shear profiles and claudication both compared favorably with those measured immediately following symptom-limited walking. A 30-min hot-water immersion is a practical means of delivering heat therapy to PAD patients and healthy, elderly individuals to induce appreciable systemic (chronotropic and blood pressure lowering) and hemodynamic (upper and lower-limb perfusion and shear rate increases) responses.

The role of intravascular ultrasound in lower limb revascularization in patients with peripheral arterial disease

2017 ◽  
Vol 36 (6) ◽  
Author(s):  
Gregory C. Makris ◽  
Pavlina Chrysafi ◽  
Mark Little ◽  
Rafiuddin Patel ◽  
Mark Bratby ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Intravascular Ultrasound ◽  
Lower Limb ◽  
Arterial Disease ◽  
Peripheral Arterial

The Role of Duplex Ultrasound in the Detection of Upper Extremity Artery Pathology, and Post Endovascular Complications

2018 ◽  
Vol 42 (1) ◽  
pp. 26-29
Author(s):  
Jason Roberts ◽  
Vaqar Ali ◽  
Mian Ahmed Hasan
Keyword(s):  
Upper Extremity ◽  
Fibromuscular Dysplasia ◽  
Duplex Ultrasound ◽  
Limb Ischemia ◽  
Arterial Disease ◽  
Upper Extremities ◽  
Peripheral Arterial ◽  
The Relationship ◽  
Abnormal Pathology

Upper extremity pathology is uncommon and generally involves the brachial artery in about 12% of the cases. Of chronic upper limb ischemia, trauma, fibromuscular dysplasia, giant cell arteritis, and atherosclerosis are among the most reported cases. After a thorough review of the literature, there is agreement with duplex ultrasound sensitivity and specificity for predicting >70% stenosis in the subclavian arteries with a sensitivity of >82% and specificity of >90%. This article not only correlates the relationship between duplex ultrasound and severe peripheral arterial disease, but it also proves with 100% accuracy the ability to detect latent and abnormal pathology of the upper extremities post endovascular intervention.

Major lower limb amputations in the elderly observed over ten years: the role of diabetes and peripheral arterial disease

2005 ◽  
Vol 31 (5) ◽  
pp. 449-454 ◽  
Author(s):  
GA Carmona ◽  
P Hoffmeyer ◽  
FR Herrmann ◽  
J Vaucher ◽  
O Tschopp ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Lower Limb ◽  
The Elderly ◽  
Arterial Disease ◽  
Peripheral Arterial
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