scholarly journals Frequency of depression in patients oFrequency of depression in patients of Chronic Hepatitis C who had not yet received treatmentf Chronic Hepatitis C who had not yet received treatment

2021 ◽  
Vol 15 (6) ◽  
pp. 1407-1410
Author(s):  
A. Adam ◽  
A. Z. K. Chachar ◽  
M. Haider ◽  
N. Yaqoob ◽  
M. Asif ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
Patient Health ◽  
Chronic Hepatitis C Patients ◽  
Hospital Protocol

Background: Chronic hepatitis C is a common entity which is frequently associated with depression. Aim: To determine the frequency of depression in patients of chronic hepatitis C who had not yet received treatment. Settings: Department of Gastroenterology and Medicine at Fatima Memorial Hospital Lahore, Pakistan. Study design: Cross sectional Descriptive study Methods: Total 217 patients were enrolled. Each patient was interviewed and then marked down by the doctor himself. Patient Health Questionnaire (PHQ 9) (annexure 2 attached) was applied to determine the presence of depression. Depression was managed as per hospital protocol. The study was conducted from 10th April, 2018 to 9th October, 2018 Results: In this study mean age was 45 years with standard deviation ± 11.33. 62% patients were male, 38% patients were female. More over 57% patients had depression while 43% patients didn’t have depression. Conclusion: Our study concluded that there was a significant association between depression and chronic hepatitis C patients before they have started their treatment, in tertiary care hospital. Keywords: Depression, chronic, hepatitis C

CLINICAL PROFILE AND THE CIRCULATING GENOTYPES OF HEPATITIS C VIRUS IN A TERTIARY CARE HOSPITAL IN WEST BENGAL

2021 ◽  
pp. 165-167
Author(s):  
Kumkum Sarkar ◽  
Rupak Chatterjee ◽  
Sumanta Sinha ◽  
Netai Pramanik
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hcv Rna ◽  
Care Hospital ◽  
Patient Department

Background and objectives- Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide, with majority of the patients being asymptomatic and when they present to clinicians, they have already advanced liver disease in form of cirrhosis or hepatocellular carcinoma. Data from developing countries on this evolving global health problem are sparse. Hence this study was planned with the aim to determine the HCV genotypes prevalant in patients attending a tertiary care hospital with their clinical prole. Materials and Methods- Detailed history taking and clinical examination were done of consecutive 30 patients who attended out-patient department or admitted at in- patient department of Tropical Medicine with chronic hepatitis C. Laboratory investigations like LFT, viral serology (HBsAg, AntiHCV, HIV), prothrombin time, ultrasonography of upper abdomen, HCV- RNA Quantative assay with genotyping were done. Data were collected and then analysed using standard statistical methods. Result- Of proposed 30 sample size, complete data could be collected of 28 patients and accordingly, analysis was done. Of the 28 HCV seroreactive individuals, majority (20) were males. The mode of transmission was unknown in 19 patients, blood transfusion in 5 patients who were thalassemic and hemodialysis in remaining 4 patients. Most of the patients (18/28) were asymptomatic even if their viral load was high. Most common presenting symptom was dyspepsia. LFT showed signicant transaminitis in 50% of the patients. Of the 28 seroreactive patients, 15 (53.57%) were HCV RNA positive based on RT-PCR. HCV rNA was below detectable level in 13 patients. HCV genotype 3 was the predominant genotype found in 11 individuals followed by genotype 1 found in 3 and genotype 2 was seen in one individual. Conclusion- Community screening specially among high risk individuals is needed for early diagnosis and prompt treatment of chronic hepatitis C to prevent its several complications and also to prevent community spread.

Clinical and epidemiological profile of patients with chronic hepatitis c in a tertiary care hospital in northern India

2013 ◽  
Vol 3 (1) ◽  
pp. S57
Author(s):  
Jayant Kumar Ghosh ◽  
Sangey Chopel Lamtha ◽  
Pankaj Kaushik ◽  
Sundeep K. Goyal ◽  
Manas K. Behra ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Northern India ◽  
Epidemiological Profile

scholarly journals CHRONIC HEPATITIS C

2018 ◽  
Vol 25 (03) ◽  
pp. 409-413
Author(s):  
Sadia Iqbal ◽  
Firasat Waqar ◽  
Aisha Javed ◽  
Nida Sajid ◽  
Tayyaba Iqbal ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Medical Department ◽  
Cross Sectional ◽  
Occult Hepatitis ◽  
B Virus

Objectives: The objective of this study is to determine the frequency of Occulthepatitis B virus (DNA) in cases of chronic hepatitis C in a tertiary care hospital of Karachi.Study Design: Cross sectional study. Setting: Medical Department of Abbasi ShaheedHospital and Karachi Medical and Dental College after permission of ethical committee.Period: 15 December 2015 to 15 December 2016. Methods: Patients greater than 18 years ofage of either sex were included while those with positive HBsAg, history of alcoholism, bloodtransfusion, intravenous drug abuse and hemodialysis were excluded. After informed consentblood samples were collected and evaluated for HBV DNA by performing qualitative PCR. Datawas analyzed on SPSS version 16.0.p value of <0.05 was taken as significant. Result: Out of377 patients with chronic Hepatitis C Occult hepatitis B virus (DNA) was found in 211 (55.9%)patients. 238(63.1%) were male and 139 (36.9%) were female. Mean age of patient with occultHBV DNA was 56.07 9.19 years. Highest prevalence 99(46.7%) was found in patients withhistory of Hepatitis C for more than three year (p value 0.02). Conclusion: Occult hepatitis Bvirus is found significantly among HCV infected patients. A masked HBV infection may interferewith the clinical outcome of chronic hepatitis C and accelerate the evolution to cirrhosis.

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