Pregnancy and endocrine disease: what is necessary to know about thyroid dysfunction? Literature review

2021 ◽  
Vol 9 (7) ◽  
Keyword(s):  
Literature Review ◽  
Thyroid Dysfunction ◽  
Endocrine Disease

scholarly journals Thyroid Dysfunction in isolated Adrenocorticotropic Hormone (ACTH) Deficiency: Case Report and Literature Review.

1993 ◽  
Vol 40 (4) ◽  
pp. 473-478 ◽  
Author(s):  
TAKEHIKO MURAKAMI ◽  
SEIKI WADA ◽  
YASUYUKI KATAYAMA ◽  
YOKO NEMOTO ◽  
NOBUO KUGAI ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Adrenocorticotropic Hormone ◽  
Thyroid Dysfunction ◽  
Acth Deficiency

The role of selenium deficiency in the development of thyroid dysfunction during pregnancy (literature review)

2020 ◽  
Vol 21 (4) ◽  
pp. 159-163
Author(s):  
G. K. Sadykova ◽  
◽  
A. A. Olina ◽  
Keyword(s):  
Insulin Resistance ◽  
Literature Review ◽  
Autoimmune Thyroiditis ◽  
Pregnancy Complications ◽  
Premature Birth ◽  
Nutritional Quality ◽  
Thyroid Dysfunction ◽  
Selenium Deficiency ◽  
Thyroid Diseases

The article presents generalized data on the influence of nutritional quality on the risk of developing gestational disorders, as well as the development of dysfunctional thyroid diseases associated with pregnancy. The role of selenium deficiency in the genesis of such pregnancy complications as preeclampsia, premature birth, as well as autoimmune thyroiditis, hypothyroidism and insulin resistance is considered. The necessity of subsidizing selenium preparations during pregnancy as a measure of preventing the development of these conditions is discussed.

Prevalence of Thyroid Dysfunction in Turner's Syndrome: A Long-Term Follow-Up Study and Brief Literature Review

Thyroid ◽  
2005 ◽  
Vol 15 (9) ◽  
pp. 1061-1066 ◽  
Author(s):  
S. Livadas ◽  
P. Xekouki ◽  
F. Fouka ◽  
C. Kanaka-Gantenbein ◽  
I. Kaloumenou ◽  
...  
Keyword(s):  
Literature Review ◽  
Thyroid Dysfunction ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Follow Up Study ◽  
Long Term Follow Up

scholarly journals Thyroid Function Abnormalities among Hospital Patients of Hilly Nepal

2017 ◽  
Vol 5 (1) ◽  
pp. 29
Author(s):  
Raj Krishna Dangol ◽  
Priya Lanjekar ◽  
Chandrashekhar Pulipati
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
College Teaching ◽  
Reproductive Age ◽  
P Value ◽  
Thyroid Disorder ◽  
Endocrine Disease ◽  
Medical College ◽  
Hilly Region ◽  
Hospital Patients

Introduction: Thyroid dysfunction stands as the second most common endocrine disease after diabetes mellitus. National reports on its prevalence are meagre. Hence, the study was conducted with the objective of exploring the prevalence of thyroid dysfunction among hospital patients of hilly region of Nepal. Methods: A hospital based, retrospective, analytical study was conducted in the department of biochemistry, Lumbini Medical College Teaching Hospital (LMCTH) from 15th February 2017 to 30th April 2017. The hospital records of patients from March 2014 to mid-February 2017 with suspected thyroid dysfunction and presented from different departments of hospital were reviewed. Data was entered in Excel 2007 and analysis was done with Statistical Package for Social Sciences (SPSS-21). Necessary descriptive and inferential statistical analysis was done. P value less than 0.05 was regarded as statistically significant. Results: Out of 3136 subjects, 601 (19.2%) were male and 2535 (80.8%) were female with F:M ratio of 4.2:1. Female were more likely to be suspected of thyroid dysfunction. Mean age of male was 39.28 years (SD = 19.01) and that of female was 39.60 years (SD = 14.63). Prevalence of thyroid dysfunction was 23.31%. Correlation of log10 TSH with age showed a significant relation (r = -0.05, p = 0.003).  Age group and thyroid function category among female patients was found to be statistically significant (p = 0.01). Conclusion: The prevalence of thyroid dysfunction was high in Tansen region, a hilly mid-west Nepal. Female above 40 yrs (post reproductive age) and male above 60 yrs (elderly group) were more prone to thyroid disorders. Also, the study revealed that younger people are more likely to be euthyroid whereas as age advances, people are likely to be either hypothyroid or hyperthyroid. These findings can be a guide for elaborative research in thyroid disorder in future.

Medico-Legal Implications of Hidden Thyroid Dysfunction: A Study of Two Cases

2000 ◽  
Vol 40 (3) ◽  
pp. 251-257 ◽  
Author(s):  
Els A De Letter ◽  
Michel H A Piette ◽  
Willy E Lambert ◽  
André P De Leenheer
Keyword(s):  
Literature Review ◽  
Sudden Death ◽  
Thyroid Hormones ◽  
Thyroid Dysfunction ◽  
Thyroid Disorders ◽  
Post Mortem ◽  
Manner Of Death ◽  
Post Mortem Examination ◽  
Legal Implications ◽  
Incidental Discovery

In this paper we present two cases in which thyroid disorders were unexpectedly brought to view. The question we ponder is whether hidden thyroid dysfunction may be important in the cause, mechanism and manner of death, or just an incidental discovery during the post-mortem examination. A short literature review has been conducted in order to evaluate previously reported cases of thyroid pathology and sudden death. The significance of post-mortem evaluation of thyroid hormones (T3 and T4) will be considered briefly.

scholarly journals MANAGEMENT OF ENDOCRINE DISEASE Subclinical hypothyroidism in children

2020 ◽  
Vol 183 (2) ◽  
pp. R13-R28
Author(s):  
Mariacarolina Salerno ◽  
Nicola Improda ◽  
Donatella Capalbo
Keyword(s):  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Current Data ◽  
Free T4 ◽  
Endocrine Disease ◽  
Cognitive Domains ◽  
Risk Of Progression ◽  
Intellectual Outcome ◽  
Serum Tsh ◽  
Tsh Levels

Subclinical hypothyroidism (SH) is biochemically defined as serum TSH levels above the upper limit of the reference range in the presence of normal free T4 (FT4) concentrations. While there is a general agreement to treat subjects with serum TSH levels above 10 mU/L, the management of mild form (TSH concentrations between 4.5 and 10 mU/L) is still a matter of debate. In children, mild SH is often a benign and remitting condition and the risk of progression to overt thyroid dysfunction depends on the underlying condition, being higher in the autoimmune forms. The major concern is to establish whether SH in children should always be considered an expression of mild thyroid dysfunction and may deserve treatment. Current data indicate that children with mild SH have normal linear growth, bone health and intellectual outcome. However, slight metabolic abnormalities and subtle deficits in specific cognitive domains have been reported in children with modest elevation of TSH concentration. Although these findings are not sufficient to recommend levothyroxine treatment for all children with mild SH, they indicate the need for regular monitoring to ensure early identification of children who may benefit from treatment. In the meanwhile, the decision to initiate therapy in children with mild SH should be based on individual factors.

scholarly journals DIAGNOSIS OF ENDOCRINE DISEASE: Limitations of the IGF1 generation test in children with short stature

2012 ◽  
Vol 166 (3) ◽  
pp. 351-357 ◽  
Author(s):  
Régis Coutant ◽  
Helmuth-Günther Dörr ◽  
Helena Gleeson ◽  
Jesús Argente
Keyword(s):  
Literature Review ◽  
Positive Predictive Value ◽  
Short Stature ◽  
European Society ◽  
Predictive Value ◽  
Treatment Decisions ◽  
Pragmatic Approach ◽  
Endocrine Disease ◽  
Paediatric Endocrinology ◽  
Generation Test

The IGF1 generation test (IGFGT) is often used during the assessment of suspected GH insensitivity (GHI). We report the results of a survey undertaken in 2010 to determine the use of IGFGT amongst members of the European Society for Paediatric Endocrinology to evaluate suspected GHI. The literature surrounding the usefulness and limitations of IGFGT are reviewed, and recommendations provided for its use. Of 112 paediatric endocrinologists from 30 countries who responded to the survey, 91 (81%) reported that they had used the IGFGT in the previous 2 years; >10 IGFGT protocols were used. The IGFGT impacted treatment decisions for 97% of the respondents and was a prerequisite for recombinant human IGF1 treatment for 45% of respondents. From a literature review, sensitivity of the IGFGT was evaluated as 77–91% in molecularly proven cases of GHI; specificity was ≤97%, depending on the protocol. The positive predictive value of the IGFGT is likely to be low, as the frequency of normality is predictably higher than that of abnormality in GH signalling. Given the limitations of the IGFGT in the most severe cases of GHI syndrome (GHIS), the ability of the IGFGT to detect less severe GHIS is doubtful. In a pragmatic approach, the IGFGT may not be useful for the diagnosis of GHIS.

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