scholarly journals Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Ola Røkke ◽  
Knut Iversen ◽  
Torill Olsen ◽  
Sølvi-May Ristesund ◽  
Geir Egil Eide ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ulcerative Colitis ◽  
Restorative Proctocolectomy ◽  
High Frequency ◽  
Functional Results ◽  
Favourable Result ◽  
Life Questionnaire ◽  
Calprotectin Level ◽  
Mucosal Changes

Objective. Study the functional results and mucosal changes in the ileal pouch after restorative proctocolectomy with J-reservoir for ulcerative colitis. Material and Methods. Followup study of 125 patients with J-reservoir with one disease-specific- and one general (SF-36) quality of life-questionnaire, rectoscopy with biopsies, and stool samples to evaluate inflammation, dysplasia, presence of Helicobacter pylori and calprotectin level. Results. Fourteen J-reservoirs were removed or deactivated, leaving 111 patients for followup. The followup time was 6.8 (1–15) years. 87.4% of the patients were satisfied. 93.1% had some kind of functional restriction: food- (75.5%), social- (28.9%), physical- (37%) or sexual restriction (15.3%). 18.6% had often or sometimes faecal incontinence. Low daytime faecal frequency was associated with good quality of life. 13 patients (12.6%) had a less favourable result. There was no pouch-dysplasia. Calprotectin levels were increased in patients with visible pouch inflammation or history of pouchitis. HP was diagnosed by RUT in 42.3%, but was not associated with inflammation or pouchitis. Conclusions. Most patients were satisfied with the J-reservoir in spite of a high frequency of various restrictions. 12.6% (13 patients) had a less favourable functional result, partly due to a high frequency of defecations, pain, pouchitis and inflammation.

scholarly journals Could Total Colectomy with Ileorectal Anastomosis Be an Alternative to Total Proctocolectomy with Ileal Pouch-Anal Anastomosis in Selected Ulcerative Colitis Patients?

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Francesco Tonelli ◽  
Carmela Di Martino ◽  
Francesco Giudici
Keyword(s):  
Quality Of Life ◽  
Ulcerative Colitis ◽  
Ileorectal Anastomosis ◽  
Bowel Function ◽  
Functional Results ◽  
Late Complications ◽  
Matched Pair ◽  
Total Proctocolectomy ◽  
Matched Pair Analysis

Purpose. To evaluate ileorectal anastomosis (IRA) in selected ulcerative colitis patients.Methods. Early and late complications after IRA and IPAA were investigated. Bowel function and quality of life were assessed. Functional and QoL studies were performed as a matched pair analysis, comparing 98 patients who underwent IRA versus 98 patients who underwent IPAA.Results. In IRA group, 2 patients (1.6%) developed anastomotic l dysplasia (HGD) developed in 3 patients dysplasia (HGD) developed in 3 patients eakage, 1 patient (0.8%) had intestinal obstruction, and 2 patients (1.6%) had abdominal hematoma. Mean follow-up was 11.5 (range: 2–24.3) years. Failure of IRA occurred in 19 patients (15.1%); in 12 patients (9.5%), failure was related to severe proctitis, in 3 patients (2.4%), it was related to the development of high-grade dysplasia, and in 4 patients (3.2%), it was related to the development of rectal cancer. About functional results, stool consistency [liquid (6.7% of IRA patients versus 29% of IPAA patients;p=0.003)], daily soiling (0% versus 6%;p=0.01), and nocturnal soiling (6% versus 25.5%;p=0.03) were statistically different. Only 1% of IRA patients versus 11% of IPAA patients had episodes of perianal inflammation (p=0.007). CGQoL was 0.72 (±0.14, SD) in IRA patients and 0.75 (±0.11, SD) in IPAA patients (p=ns).Conclusion. In selected patients, IRA is an appropriate surgical option, with low morbidity, comparable quality of life, and better functional results than IPAA.

scholarly journals Head and Neck Osteosarcoma—The Ongoing Challenge about Reconstruction and Dental Rehabilitation

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1948 ◽  
Author(s):  
Andrea Cassoni ◽  
Edoardo Brauner ◽  
Resi Pucci ◽  
Valentina Terenzi ◽  
Nicolò Mangini ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck ◽  
Functional Results ◽  
Life Questionnaire ◽  
Prosthetic Rehabilitation ◽  
European Organization ◽  
Aesthetic Result ◽  
Dental Rehabilitation ◽  
Eortc Qlq

Head and Neck osteosarcoma is an uncommon disease. Hitherto, the treatment is surgical resection and survival is influenced by the presence of free margins. However, the dimension of the resection may represent a hurdle for an adequate Quality of Life (QOL). Maxillofacial district is a narrow space where the function, esthetics and patient’s relational skills fit together like the gears of a clock. The functional results depend on the type of reconstruction and prosthetic rehabilitation that are both important to guarantee a good aesthetic result and finally increase the patient’s self-esteem. This study aims to report our experience about head and neck (HN) osteosarcoma focusing the attention on reconstructive and dental-rehabilitative problems. It is a retrospective study all patients were surgically treated in our department. Subjects with histological diagnosis of HN osteosarcoma, treated between 2005 and 2017 were included. The demographic characteristics, surgical treatment, eventually secondary reconstruction and prosthetic rehabilitation, performed in the same department, have been collected. The QOL was assessed through the EORTC QLQ-H&N35 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35) questionnaire. Fifteen patients were enrolled, eight received a free flap microsurgical reconstruction. Dental rehabilitation was performed in five cases and a mobile prosthesis was always delivered. Eighteen implants were inserted in fibula bones for three patients; highly porous implants were used.

scholarly journals P065 - Medina catheter use following restorative proctocolectomy for ulcerative colitis: quality of life and functional outcome

2009 ◽  
Vol 3 (1) ◽  
pp. S36
Author(s):  
S.D. McLaughlin ◽  
S.K. Clark ◽  
Z.L. Perry-Woodford ◽  
P.P. Tekkis ◽  
P.J. Ciclitira ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ulcerative Colitis ◽  
Functional Outcome ◽  
Restorative Proctocolectomy
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