Effect of food intake on the bioavailability of almotriptan, an antimigraine compound, in healthy volunteers: an open, randomized, crossover, single-dose clinical trial

2006 ◽  
Vol 44 (04) ◽  
pp. 185-190 ◽  
Author(s):  
J.M. Jansat ◽  
A. Martinez-Tobed ◽  
E. Garcia ◽  
X. Cabarrocas ◽  
J. Costa
Keyword(s):  
Clinical Trial ◽  
Single Dose ◽  
Food Intake ◽  
Healthy Volunteers ◽  
Effect Of Food

Pharmacokinetics of Pregabalin Controlled-Release in Healthy Volunteers: Effect of Food in Five Single-Dose, Randomized, Clinical Pharmacology Studies

2014 ◽  
Vol 34 (9) ◽  
pp. 617-626 ◽  
Author(s):  
Marci L. Chew ◽  
Anna Plotka ◽  
Christine W. Alvey ◽  
Verne W. Pitman ◽  
Tanja Alebic-Kolbah ◽  
...  
Keyword(s):  
Clinical Pharmacology ◽  
Single Dose ◽  
Controlled Release ◽  
Healthy Volunteers ◽  
Effect Of Food

Comparative Effect of Food on Absorption of Ampicillin and Pivampicillin

1977 ◽  
Vol 5 (1) ◽  
pp. 71-76 ◽  
Author(s):  
P J Neuvonen ◽  
E Elonen ◽  
P J Pentikäinen
Keyword(s):  
Food Intake ◽  
Serum Concentration ◽  
Urinary Excretion ◽  
Crossover Study ◽  
Healthy Volunteers ◽  
Total Absorption ◽  
Comparative Effect ◽  
Concentration Time ◽  
Ampicillin Concentration ◽  
Effect Of Food

The effect of food on the absorption of simultaneously ingested ampicillin or pivampicillin was compared in a crossover study in eight healthy volunteers. The absorption of both ampicillin and pivampicillin was delayed by simultaneous food intake as judged by serum concentration and urinary excretion of ampicillin. The total absorption of ampicillin, but not that of pivampicillin was decreased by simultaneous food intake as indicated by the area under the serum ampicillin concentration-time curves and by 24 hours urinary excretion of ampicillin. The excretion of ampicillin into urine was about 30% of the dose when ampicillin was ingested with water into an empty stomach and about 20% when ingested with food. The respective excretion of ampicillin following the ingestion of pivampicillin was about 60% of the dose taken either with or without food.

Effect of Food on the Single‐dose Pharmacokinetics and Tolerability of Savolitinib in Chinese Healthy Volunteers

2021 ◽  
Author(s):  
Qichen Ding ◽  
Meixian OU ◽  
Huijuan Zhu ◽  
Yijun Wang ◽  
Jingying Jia ◽  
...  
Keyword(s):  
Single Dose ◽  
Healthy Volunteers ◽  
Effect Of Food

Effect of food on the single-dose pharmacokinetics and tolerability of clinofibrate tablets in Chinese healthy volunteers

2013 ◽  
Vol 51 (08) ◽  
pp. 672-677
Author(s):  
Jian-kang Li ◽  
Li-kun Ding ◽  
Xue-qin Li ◽  
Min-chun Chen ◽  
Lei Wang ◽  
...  
Keyword(s):  
Single Dose ◽  
Healthy Volunteers ◽  
Effect Of Food
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