Background: The causes of upper extremity radicular pain or neck pain are varied, often involving
disc herniation, spinal stenosis, or spondylosis. Cervical transformaminal epidural steroid injection
(C-TFESI) is a common treatment for such pain. However, its efficacy conceivably may depend on
needle-tip placement, linking the degree of pain reduction achieved to the pattern of contrast
dispersion.
Objective: The current study explores this relationship, evaluating contrast dispersion patterns of
C-TFESI in conjunction with short-term patient outcomes.
Study Design: Prospective evaluation.
Methods: A total of 67 patients with cervical radicular pain were enrolled, each of whom
underwent computed tomography (CT)-guided C-TFESI. Procedural contrast dispersion was
judged as either intraforaminal or extraforaminal. Using the Roland 5-point pain scale, outcomes
were scored 2 weeks after injection and then grouped as improvement (scores, 0 – 2) or no
improvement (scores, 3 – 5).
Results: Contrast dispersion was largely intraforaminal (50 patients), as opposed to extraforaminal
(17 patients), with no statistically significant difference in short-term pain relief by contrast pattern
(intraforaminal: 56%, 28/50; extraforaminal: 53%, 9/17; P = 0.459). Of the 50 procedures where
dispersion of contrast was intraforaminal, 44% (22/50) were scored as unfavorable outcomes.
Limitations: Small sample size, brief follow-up, and secondary outcomes were not measured.
Authors also did not analyze other variables impacting C-TFESI, and classifying patterns of contrast
spread anatomically as epidural or epiradicular (one, both, or neither as applicable) is simply not
feasible by CT.
Conclusion: C-TFESI is an effective treatment for cervical radicular pain that is refractory to
conventional conservative remedies. However, therapeutic response to C-TFESI and dispersion
pattern of injected contrast failed to correlate in this study.
Key words: Cervical, epidural, contrast, CT-guided, TFESI